Patents by Inventor Raeann Wu

Raeann Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts of aza-bicyclic di-aryl ethers and methods to make them or their precursors
    Patent number: 10421755
    Abstract: The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: September 24, 2019
    Assignee: Novartis AG
    Inventors: Wolfgang Marterer, Mahavir Prashad, Edwin Bernard Villhauer, Liladhar Murlidhar Waykole, James Anthony Vivelo, Bertrand Sutter, Jean-Claude Bianchi, Raeann Wu, Denis Har, Piotr H. Karpinski, Massimo Pignone, Doris Stingelin, Eckart Buerger
  • SALTS OF AZA-BICYCLIC DI-ARYL ETHERS AND METHODS TO MAKE THEM OR THEIR PRECURSORS
    Publication number: 20180009801
    Abstract: The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 11, 2018
    Inventors: Wolfgang Marterer, Mahavir Prashad, Edwin Bernard Villhauer, Liladhar Murlidhar Waykole, James Anthony Vivelo, Bertrand Sutter, Jean-Claude Bianchi, Raeann Wu, Denis Har, Piotr H. Karpinski, Massimo Pignone, Doris Stingelin, Eckart Buerger
  • Salts of aza-bicyclic di-aryl ethers and methods to make them or their precursors
    Patent number: 9802931
    Abstract: The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: October 31, 2017
    Assignee: Novartis AG
    Inventors: Wolfgang Marterer, Mahavir Prashad, Edwin Bernard Villhauer, Liladhar Murlidhar Waykole, James Anthony Vivelo, Bertrand Sutter, Jean-Claude Bianchi, Raeann Wu, Denis Har, Piotr H. Karpinski, Massimo Pignone, Doris Stingelin, Eckart Buerger
  • L-tartrate salt of pridopidine
    Patent number: 9796673
    Abstract: The subject invention provides pridopidine L-tartrate, compositions and a process for manufacture thereof.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 24, 2017
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Raeann Wu, Ralph Curtis Haltiwanger, Stephen Bierlmaier, Mehran Yazdanian
  • L-TARTRATE SALT OF PRIDOPIDINE
    Publication number: 20160176821
    Abstract: The subject invention provides pridopidine L-tartrate, compositions and a process for manufacture thereof.
    Type: Application
    Filed: December 18, 2015
    Publication date: June 23, 2016
    Applicant: Teva Pharmaceuticals International GmbH
    Inventors: Raeann Wu, Ralph Curtis Haltiwanger, Stephen Bierlmaier, Mehran Yazdanian
  • Salts of aza-bicyclic di-aryl ethers and pharmaceuticals thereof
    Patent number: 9365565
    Abstract: The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: June 14, 2016
    Assignee: Novartis AG
    Inventors: Wolfgang Marterer, Mahavir Prashad, Edwin Bernard Villhauer, Liladhar Murlidhar Waykole, James Anthony Vivelo, Bertrand Sutter, Jean-Claude Bianchi, Raeann Wu, Denis Har, Piotr H. Karpinski, Massimo Pignone, Doris Stingelin, Eckart Buerger
  • SALTS OF AZA-BICYCLIC DI-ARYL ETHERS AND METHODS TO MAKE THEM OR THEIR PRECURSORS
    Publication number: 20160145253
    Abstract: The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
    Type: Application
    Filed: January 15, 2016
    Publication date: May 26, 2016
    Inventors: Wolfgang Marterer, Mahavir Prashad, Edwin Bernard Villhauer, Liladhar Murlidhar Waykole, James Anthony Vivelo, Bertrand Sutter, Jean-Claude Bianchi, Raeann Wu, Denis Har, Piotr H. Karpinski, Massimo Pignone, Doris Stingelin, Eckart Buerger
  • Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Patent number: 9163005
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: October 20, 2015
    Assignee: Novartis AG
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Crystalline forms of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl) -phenylamino]-pyrimidin-4-yl}-1-methyl-urea and salts thereof
    Patent number: 9067896
    Abstract: The present technology provides novel anhydrous and hydrated crystalline forms of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea, amorphous and anhydrous crystalline polymorphs of its monophosphoric acid salt, and the hydrochloride salt, including its dihydrate. The present technology further provides methods for preparing the various forms, compositions containing them, and methods of treatment employing them.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: June 30, 2015
    Assignee: Novartis AG
    Inventors: Joerg Berghausen, Prasad K Kapa, Joseph McKenna, Joel Slade, Raeann Wu, Zhengming Du, Frank Stowasswer
  • Crystalline Forms of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Publication number: 20140343087
    Abstract: Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Application
    Filed: August 1, 2014
    Publication date: November 20, 2014
    Applicant: Novartis AG
    Inventors: Paul W. Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H. Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Patent number: 8829015
    Abstract: Crystalline forms of 4-methyl-N-3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: September 9, 2014
    Assignee: Novartis AG
    Inventors: Paul W. Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr “Peter” H. Karpinski, Raeann Wu, Stephanie Monnier, Jörg Brozio
  • SALTS OF AZA-BICYCLIC DI-ARYL ETHERS AND METHODS TO MAKE THEM OR THEIR PRECURSORS
    Publication number: 20140220125
    Abstract: The present invention relates to salts of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane, to methods for making them or their precursors, to pharmaceutical compositions comprising them, and to their use as medicaments.
    Type: Application
    Filed: July 12, 2012
    Publication date: August 7, 2014
    Applicant: NOVARTIS AG
    Inventors: Wolfgang Marterer, Mahavir Prashad, Edwin Bernard Villhauer, Liladhar Murlidhar Waykole, James Anthony Vivelo, Bertrand Sutter, Jean-Claude Bianchi, Raeann Wu, Denis Har, Piotr H. Karpinski, Massimo Pignone, Doris Stingelin, Eckart Buerger
  • Salts of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Publication number: 20140038994
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Application
    Filed: October 11, 2013
    Publication date: February 6, 2014
    Applicant: Novartis AG
    Inventors: Paul W. MANLEY, Wen-Chung SHIEH, Paul Allen SUTTON, Piotr H. KARPINSKI, Raeann WU, Stéphanie MONNIER, Jörg BROZIO
  • Salts of 4-methyl N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Patent number: 8580806
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: November 12, 2013
    Assignee: Novartis AG
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Salts of 4-methyl N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Patent number: 8389537
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: March 5, 2013
    Assignee: Novartis AG
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • Crystalline Forms of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Publication number: 20130023548
    Abstract: Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Application
    Filed: August 3, 2012
    Publication date: January 24, 2013
    Inventors: Paul W. MANLEY, Wen-Chung SHIEH, Paul Allen SUTTON, Piotr H. KARPINSKI, Raeann WU, Stéphanie MONNIER, Jörg BROZIO
  • Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Patent number: 8343984
    Abstract: Polymorphic forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: January 1, 2013
    Assignees: Novartis AG, Novartis Pharma GmbH
    Inventors: Paul W Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr “Peter” H Karpinski, Raeann Wu, Stéphanie M. Monnier, Jörg Brozio
  • Salts of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
    Publication number: 20120270891
    Abstract: Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide are prepared by various processes.
    Type: Application
    Filed: March 13, 2012
    Publication date: October 25, 2012
    Inventors: Paul W. Manley, Wen-Chung Shieh, Paul Allen Sutton, Piotr H. Karpinski, Raeann Wu, Stéphanie Monnier, Jörg Brozio
  • CRYSTALLINE FORMS OF 3-(2,6-DICHLORO-3,5-DIMETHOXY-PHENYL)-1--1-METHYL-UREA AND SALTS THEREOF
    Publication number: 20120245182
    Abstract: The present technology provides novel anhydrous and hydrated crystalline forms of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea, amorphous and anhydrous crystalline polymorphs of its monophosphoric acid salt, and the hydrochloride salt, including its dihydrate. The present technology further provides methods for preparing the various forms, compositions containing them, and methods of treatment employing them.
    Type: Application
    Filed: December 6, 2010
    Publication date: September 27, 2012
    Inventors: Joerg Berghausen, Prasad K. Kapa, Joseph McKenna, Joel Slade, Raeann Wu, Zhengming Du, Frank Stowasswer
  • Salts of N-[6-cis-2,6-Dimethylmorpholin-4-yl)pyridine-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
    Publication number: 20120214810
    Abstract: Salts of N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridine-3-yl]-2-methyl-4?-(trifluoromethoxy)[1,1?-biphenyl]-3-carboxamide are prepared and characterized.
    Type: Application
    Filed: May 2, 2012
    Publication date: August 23, 2012
    Applicant: NOVARTIS AG
    Inventors: Joginder Singh Bajwa, Marilyn De La Cruz, Stephanie Kay Dodd, Liladhar Murlidhar Waykole, Raeann Wu