Patents by Inventor Raed Abu-Reziq
Raed Abu-Reziq has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230172195Abstract: The present invention provides microcapsules encapsulating hydrophilic or hydrophobic active agents in an inorganic shell, processes for their preparation and compositions comprising them.Type: ApplicationFiled: November 22, 2018Publication date: June 8, 2023Applicant: Yissrm Research Developmet Company of The Hebrew University of Jerusalem Ltd.Inventors: Raed ABU-REZIQ, Charlie BATARSEH, Ahmad ZAROUR, Yafit SCHNELL, Amani ZOABI, Suzana NATOUR, Suheir OMAR, Esti WESS
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Patent number: 11248018Abstract: Disclosed herein is a process for preparing nicotinamide riboside (NR) from an NR precursor and a phosphate-binding agent in a solvent. The reaction-derived mixture comprising NR may be further used without further processing in a variety of products, particularly in a cosmetic product.Type: GrantFiled: February 21, 2017Date of Patent: February 15, 2022Assignees: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., HIKARI LABORATORIES LTD.Inventors: Dmitri Gelman, Amani Zoabi, Assaf Zeira, Raed Abu-Reziq
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METHOD FOR PREPARING PARTICLES COMPRISING METAL OXIDE COATING AND PARTICLES WITH METAL OXIDE COATING
Publication number: 20210007996Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.Type: ApplicationFiled: September 10, 2020Publication date: January 14, 2021Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer TOLEDANO, Haim Bar-Simantov, Nissim Bilman, Leora Shapiro, Raed Abu-Reziq, Hanan Sertchook -
METHOD FOR PREPARING PARTICLES COMPRISING METAL OXIDE COATING AND PARTICLES WITH METAL OXIDE COATING
Publication number: 20200383927Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.Type: ApplicationFiled: August 25, 2020Publication date: December 10, 2020Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer TOLEDANO, Haim BAR-SIMANTOV, Nissim BILMAN, Leora SHAPIRO, Raed ABU-REZIQ, Hanan SERTCHOOK -
Patent number: 10688462Abstract: The present invention provides a process for preparing microcapsules comprising a core material encapsulated by a metal oxide shell, microcapsules obtained therewith and uses thereof.Type: GrantFiled: August 2, 2009Date of Patent: June 23, 2020Assignee: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer Toledano, Hanan Sertchook, Natalia Loboda, Raed Abu-Reziq
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Publication number: 20200114327Abstract: The present invention provides a process for preparing microcapsules comprising a core material encapsulated by a metal oxide shell, microcapsules obtained therewith and uses thereof.Type: ApplicationFiled: December 12, 2019Publication date: April 16, 2020Applicant: Sol-Gel Technologies Ltd.Inventors: Ofer TOLEDANO Olfer TOLEDANO, Hanan Sertchook, Natalia Loboda, Raed Abu-Reziq
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Patent number: 10525433Abstract: A process for preparing nanocapsules having a core-shell structure, comprising: (a) preparing an oil-in-water emulsion by emulsification of an oily phase that comprises a core material, in an aqueous phase, under high shear forces, wherein one or both of the oily phase, and the aqueous phase comprises a sol-gel precursor; (b) subjecting the emulsion obtained in (a) to a high pressure homogenization to obtain a nano-emulsion; and (c) applying conditions for hydrolyzing and polycondensing the sol-gel precursor to obtain nanocapsules having a metal oxide shell encapsulating the core material, said nanocapsules have a particle size distribution of: d10=10-80 nm, d50=30-200 nm, and d90=70-500 nm, in diameter. The invention also relate to nanocapsules having the above particle size distribution and to composition comprising the nanocapsules.Type: GrantFiled: December 12, 2007Date of Patent: January 7, 2020Assignee: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer Toledano, Hanan Sertchook, Raed Abu-Reziq, Haim Bar-Simantov, Leora Shapiro
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Publication number: 20190055275Abstract: Disclosed herein is a process for preparing nicotinamide riboside (NR) from an NR precursor and a phosphate-binding agent in a solvent. The reaction-derived mixture comprising NR may be further used without further processing in a variety of products, particularly in a cosmetic product.Type: ApplicationFiled: February 21, 2017Publication date: February 21, 2019Inventors: Dmitri GELMAN, Amani ZOABI, Assaf ZEIRA, Raed ABU-REZIQ
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Patent number: 9643168Abstract: The present invention provides a composite comprising at least one hydrophobic organic compound and a matrix of at least one metal; wherein said at least one hydrophobic compound is entrapped within said matrix, compositions comprising at least one composite and methods of its preparation.Type: GrantFiled: May 20, 2010Date of Patent: May 9, 2017Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.Inventors: David Avnir, Raed Abu-Reziq, Rachael Ben Knaz, Itzik Yosef, Guy Nesher, Gad Marom
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Patent number: 9561485Abstract: The present invention relates to a microcapsule exhibiting desirable sustained-release properties, which microcapsule comprises a core material comprising an active ingredient encapsulated within a silica shell, characterized in that the outer surface of such silica shell has a layer of a metal selected from Group 2a, Group 8, Group 2b or Group 3a of the Periodic Table bound thereto. In other aspects this invention relates to a method of making such a microcapsule; a pesticidal composition comprising microcapsules comprising a pesticidal active ingredient and a suitable carrier; and to a method of controlling pests comprising applying an effective amount of such a pesticidal composition to a locus where pests are or are expected to be present.Type: GrantFiled: December 6, 2010Date of Patent: February 7, 2017Assignee: Sol-Gel Technologies Ltd.Inventors: Laibin Bruce Yan, Craig Arlen Martin, Raed Abu-Reziq
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Patent number: 8617580Abstract: The invention relates to a composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient. The invention further relates to method for treating a surface condition in a subject using said composition, a method for preparing a composition exhibiting improved stability, and a kit comprising: (a) a first composition comprising a peroxide as a first active ingredient; and (b) a second composition comprising a retinoid as a second active ingredient; at least one of said first and said second active ingredient being coated by a metal oxide layer.Type: GrantFiled: June 13, 2012Date of Patent: December 31, 2013Assignee: Sol-Gel Technologies Ltd.Inventors: Ofer Toledano, Hanan Sertchook, Natalia Loboda, Haim Bar-Simantov, Leora Shapiro, Raed Abu-Reziq
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Publication number: 20120295790Abstract: The present invention relates to a microcapsule exhibiting desirable sustained-release properties, which microcapsule comprises a core material comprising an active ingredient encapsulated within a silica shell, characterized in that the outer surface of such silica shell has a layer of a metal selected from Group 2a, Group 8, Group 2b or Group 3a of the Periodic Table bound thereto. In other aspects this invention relates to a method of making such a microcapsule; a pesticidal composition comprising microcapsules comprising a pesticidal active ingredient and a suitable carrier; and to a method of controlling pests comprising applying an effective amount of such a pesticidal composition to a locus where pests are or are expected to be present.Type: ApplicationFiled: December 6, 2010Publication date: November 22, 2012Applicants: SOL-GEL TECHNOLOGIES LTD., FMC CORPORATIONInventors: Laibin Bruce Yan, Craig Arlen Martin, Raed Abu-Reziq
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Publication number: 20120269874Abstract: The invention relates to a composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient. The invention further relates to method for treating a surface condition in a subject using said composition, a method for preparing a composition exhibiting improved stability, and a kit comprising: (a) a first composition comprising a peroxide as a first active ingredient; and (b) a second composition comprising a retinoid as a second active ingredient; at least one of said first and said second active ingredient being coated by a metal oxide layer.Type: ApplicationFiled: June 13, 2012Publication date: October 25, 2012Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer TOLEDANO, Hanan SERTCHOOK, Natalia LOBODA, Haim BAR-SIMANTOV, Leora SHAPIRO, Raed ABU-REZIQ
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Publication number: 20110177951Abstract: The present invention provides a process for preparing microcapsules comprising a core material encapsulated by a metal oxide shell, microcapsules obtained therewith and uses thereof.Type: ApplicationFiled: August 2, 2009Publication date: July 21, 2011Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer Toledano, Hanan Sertchook, Natalia Loboda, Raed Abu-Reziq
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Publication number: 20100297724Abstract: The present invention provides a composite comprising at least one hydrophobic organic compound and a matrix of at least one metal; wherein said at least one hydrophobic compound is entrapped within said matrix, compositions comprising at least one composite and methods of its preparation.Type: ApplicationFiled: May 20, 2010Publication date: November 25, 2010Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEMInventors: David AVNIR, Raed ABU-REZIQ, Rachael BEN KNAZ, Itzik YOSEF, Guy NESHER, Gad MAROM
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Publication number: 20100203121Abstract: A process for preparing nanocapsules having a core-shell structure, comprising: (a) preparing an oil-in-water emulsion by emulsification of an oily phase that comprises a core material, in an aqueous phase, under high shear forces, wherein one or both of the oily phase, and the aqueous phase comprises a sol-gel precursor; (b) subjecting the emulsion obtained in (a) to a high pressure homogenization to obtain a nano-emulsion; and (c) applying conditions for hydrolyzing and polycondensing the sol-gel precursor to obtain nanocapsules having a metal oxide shell encapsulating the core material, said nanocapsules have a particle size distribution of: d10=10-80 nm, d50=30-200 nm, and d90=70-500 nm, in diameter. The invention also relate to nanocapsules having the above particle size distribution and to composition comprising the nanocapsules.Type: ApplicationFiled: December 12, 2007Publication date: August 12, 2010Applicant: SOL-GEL TECHNOLOGIES, LTD.Inventors: Ofer Toledano, Hanan Sertchook, Raed Abu-Reziq, Haim Bar-Simantov, Leora Shapiro
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Publication number: 20100047357Abstract: The invention relates to a composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient. The invention further relates to method for treating a surface condition in a subject using said composition, a method for preparing a composition exhibiting improved stability, and a kit comprising: (a) a first composition comprising a peroxide as a first active ingredient; and (b) a second composition comprising a retinoid as a second active ingredient; at least one of said first and said second active ingredient being coated by a metal oxide layer.Type: ApplicationFiled: February 3, 2008Publication date: February 25, 2010Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer Toledano, Hanan Sertchook, Natalia Loboda, Haim Bar-Simantov, Leora Shapiro, Raed Abu-Reziq
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METHOD FOR PREPARING PARTICLES COMPRISING METAL OXIDE COATING AND PARTICLES WITH METAL OXIDE COATING
Publication number: 20100016443Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.Type: ApplicationFiled: February 3, 2008Publication date: January 21, 2010Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer Toledano, Haim Bar-Simantov, Nissim Bilman, Leora Shapiro, Raed Abu-Reziq, Srikanth Sriadibhatla, William T. Sommer