Patents by Inventor Rafael Rubio

Rafael Rubio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and devices for solid structure formation by localized microwaves
    Patent number: 9578695
    Abstract: Method and device for solid structure formation by localized microwaves for additive fabrication of solid bodies by use of localized microwave radiation applied to a source material, in the form of a powder, wire or other solid form, so as to generate a hotspot in a thermal-runaway process or through plasma breakdown, and melt a small portion of it (with at least one dimension smaller than the microwave wavelength) thereby consolidating small pieces of the molten source material in a stepwise manner to construct the entire body.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: February 21, 2017
    Assignees: Fundacio Privada ASCAMM
    Inventors: Eli Jerby, Alon Salzberg, Yehuda Meir, Francisco Javier Planta Torralba, Rafael Rubio Bonilla, Benjamin Cavallini
  • METHOD AND DEVICES FOR SOLID STRUCTURE FORMATION BY LOCALIZED MICROWAVES
    Publication number: 20140021171
    Abstract: Method and device for solid structure formation by localized microwaves for additive fabrication of solid bodies by use of localized microwave radiation applied to a source material, in the form of a powder, wire or other solid form, so as to generate a hotspot in a thermal-runaway process or through plasma breakdown, and melt a small portion of it (with at least one dimension smaller than the microwave wavelength) thereby consolidating small pieces of the molten source material in a stepwise manner to construct the entire body.
    Type: Application
    Filed: September 24, 2013
    Publication date: January 23, 2014
    Inventors: Eli Jerby, Alon Salzberg, Yehuda Meir, Francisco Xavier Planta Torralba, Rafael Rubio Bonilla, Benjamin Cavallini
  • Adenosine dextran conjugates
    Patent number: 5424297
    Abstract: Covalent conjugates of water soluble dextrans and adenosine agonists or antagonists wherein the dextran is coupled through the C6 or C8 positions of the purine ring. These compounds activate or block adenosine A.sub.1 or A.sub.2 receptors are useful in treating hypertension.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: June 13, 1995
    Assignee: University of Virginia Alumni Patents Foundation
    Inventors: Rafael Rubio, Eduardo Balcells, Jorge Suarez
  • Adenosine in the treatment of supraventricular tachycardia
    Patent number: 4673563
    Abstract: A method of diagnosing and treating arrhythmias caused by re-entry in the A-V node by administering to a human or animal an effective amount of adenosine that restores normal sinus rhythm.
    Type: Grant
    Filed: April 8, 1985
    Date of Patent: June 16, 1987
    Assignee: The University of Virginia Alumni Patents Foundation
    Inventors: Robert M. Berne, Luiz Belardinelli, Rafael Rubio
  • Adenosine antagonists in the treatment and diagnosis of A-V node conduction disturbances
    Patent number: 4364922
    Abstract: A method of relieving atrioventricular conduction block by administering to a human or animal an effective amount of an adenosine antagonist that competitively inhibits adenosine or that reduces the level of adenosine present in myocardial tissue and associated fluids. A method of diagnosing atrioventricular conduction block caused by ischemia of the heart by measuring the time delay between atrial and ventricular excitation before and after the administration of an adenosine antagonist. Specific antagonists disclosed include methylxanthines.
    Type: Grant
    Filed: October 14, 1980
    Date of Patent: December 21, 1982
    Assignee: University of Virginia Alumni Patents Foundation
    Inventors: Robert M. Berne, Luiz Belardinelli, Rafael Rubio