Patents by Inventor Raghbir S. Bhullar
Raghbir S. Bhullar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8679853Abstract: A test strip or biosensor comprising a base substrate on which an electrode system is formed. One or more laminate layers overlie the base substrate to form a sample-receiving chamber in which a reagent is deposited. An opening is provided from the sample-receiving chamber to the exterior of the biosensor. The layers and the base substrate are laser welded to secure the biosensor. One of the layer and base substrate is light transmissive to allow laser welding at the interface therebetween. The biosensor may be formed from a series of continuous webs that are subsequently sliced to form individual biosensors.Type: GrantFiled: July 3, 2007Date of Patent: March 25, 2014Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Ali Razban
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Patent number: 8551308Abstract: An electrochemical biosensor with electrode elements that possess smooth, high-quality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds—without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.Type: GrantFiled: September 25, 2008Date of Patent: October 8, 2013Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.Inventors: Raghbir S. Bhullar, Eric R. Diebold, Brian S. Hill, Nigel Surridge, Paul Douglas Walling
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Patent number: 8287703Abstract: An electrochemical biosensor with electrode elements that possess smooth, high-quality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds—without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.Type: GrantFiled: September 25, 2008Date of Patent: October 16, 2012Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.Inventors: Raghbir S. Bhullar, Eric R. Diebold, Brian S. Hill, Nigel Surridge, Paul Douglas Walling
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Patent number: 8222044Abstract: A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to “target” with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.Type: GrantFiled: November 16, 2011Date of Patent: July 17, 2012Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.Inventors: Raghbir S. Bhullar, Nigel Surridge, Tom Funke, Paul Douglas Walling, Randall K. Riggles
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Publication number: 20120055626Abstract: A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to “target” with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.Type: ApplicationFiled: November 16, 2011Publication date: March 8, 2012Inventors: Raghbir S. Bhullar, Nigel Surridge, Tom Funke, Paul Douglas Walling, Randall K. Riggles
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Patent number: 8071030Abstract: A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to “target” with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.Type: GrantFiled: June 18, 2004Date of Patent: December 6, 2011Assignees: Roche Diagnostics Operations, Inc., Roche Operations Ltd.Inventors: Raghbir S. Bhullar, Nigel Surridge, Tom Funke, Paul Douglas Walling, Randall K. Riggles
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Patent number: 7867369Abstract: A biosensor having multiple electrical functionalities located both within and outside of the measurement zone in which a fluid sample is interrogated. Incredibly small and complex electrical patterns with high quality edges provide electrical functionalities in the biosensor and also provide the electrical wiring for the various other electrical devices provided in the inventive biosensor. In addition to a measurement zone with multiple and various electrical functionalities, biosensors of the present invention may be provided with a user interface zone, a digital device zone and/or a power generation zone. The inventive biosensors offer improved ease of use and performance, and decrease the computational burden and associated cost of the instruments that read the biosensors by adding accurate yet cost-effective functionalities to the biosensors themselves.Type: GrantFiled: June 18, 2004Date of Patent: January 11, 2011Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Harvey B. Buck, Jr., Brian S. Hill, Paul Douglas Walling, Terry A. Beaty, David W. Burke, Eric R. Diebold
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Publication number: 20100219071Abstract: The present invention relates to a biosensor. The biosensor includes a support substrate, an electrically conductive coating positioned on the support substrate, the coating being formed to define electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and a cover cooperating with the support substrate to define a channel. At least a portion of the electrodes are positioned in the channel.Type: ApplicationFiled: June 22, 2005Publication date: September 2, 2010Inventors: Raghbir S. Bhullar, Henning Groll, John T. Austera, Douglas P. Walling, Timothy I. Ranney, James L. Pauley, JR.
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Patent number: 7780827Abstract: The present invention relates to a biosensor. The biosensor includes a support substrate, an electrically conductive coating positioned on the support substrate, the coating being formed to define electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and a cover cooperating with the support substrate to define a channel. At least a portion of the electrodes are positioned in the channel.Type: GrantFiled: June 22, 2005Date of Patent: August 24, 2010Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Henning Groll, John T. Austera, Douglas P. Walling, Timothy L. Ranney, James L. Pauley, Jr.
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Publication number: 20090056120Abstract: An electrochemical biosensor with electrode elements that possess smooth, high-quality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds—without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.Type: ApplicationFiled: September 25, 2008Publication date: March 5, 2009Inventors: Raghbir S. Bhullar, Eric R. Diebold, Brian S. Hill, Nigel Surridge, Paul Douglas Walling
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Publication number: 20090020502Abstract: An electrochemical biosensor with electrode elements that possess smooth, high-quality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds—without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.Type: ApplicationFiled: September 25, 2008Publication date: January 22, 2009Inventors: Raghbir S. Bhullar, Eric R. Diebold, Brian S. Hill, Nigel Surridge, Paul Douglas Walling
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Patent number: 7479211Abstract: A method of forming a biosensor is provided in accordance with the present invention. The method includes providing a metallized electrode support substrate and a sensor support, ablating the electrode support substrate to form electrodes, coupling the sensor support substrate to the electrode support substrate, and positioning spaced-apart electrically conductive tracks across the sensor support substrate so that each track is in electrical communication with one electrode.Type: GrantFiled: May 13, 2004Date of Patent: January 20, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, John T. Austera, Brian S. Hill, Christopher D. Wilsey
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Patent number: 7476827Abstract: The present invention relates to a method of forming a biosensor. The method includes providing a substrate coated with a electrically conductive material, ablating the electrically conductive material to form electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and applying a reagent to at least one of the electrodes.Type: GrantFiled: October 29, 2004Date of Patent: January 13, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Henning Groll, John T. Austera, Douglas P. Walling, Timothy L. Ranney, James L. Pauley, Jr.
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Patent number: 7473398Abstract: The present invention relates to a biosensor. The biosensor includes a support substrate having first and second ends, electrodes positioned on the support substrate, the electrodes cooperating with one another to define electrode arrays situated adjacent to the first end, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a channel. The channel includes an inlet adjacent to the first end and opposite ends. Each electrode array is positioned in the channel adjacent to one of the ends.Type: GrantFiled: May 25, 2001Date of Patent: January 6, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Christopher D. Wilsey, John T. Austera, Wolfgang O. L. Reiser
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Publication number: 20080314882Abstract: The present invention relates to a method of forming a biosensor. The method includes providing a substrate coated with a electrically conductive material, ablating the electrically conductive material to form electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and applying a reagent to at least one of the electrodes.Type: ApplicationFiled: October 29, 2004Publication date: December 25, 2008Inventors: Raghbir S. Bhullar, Henning Groll, John T. Austera, Douglas P. Walling, Timothy L. Ranney, James L. Pauley, JR.
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Patent number: 7386937Abstract: A method of making a biosensor is provided. The method includes providing an electrically conductive material on a base and partially removing the conductive material using laser ablation from the base so that less than 90% of the conductive material remains on the base and at least one electrode pattern is formed from the conductive material. The at least one electrode pattern has an edge extending between two points. A standard deviation of the edge from a line extending between two points is less than about 6 ?m along the length of the edge.Type: GrantFiled: May 1, 2006Date of Patent: June 17, 2008Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Eric R. Diebold, Brian S. Hill, Nigel A. Surridge, Douglas P. Walling
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Patent number: 7287318Abstract: A biosensor is provided that comprises a plate element with a pre-determined reaction zone and a recess positioned adjacent to the reaction zone. The biosensor also comprises a reagent that is positioned on the reaction zone. In preferred embodiments, the recess circumscribes at least a portion of the reaction zone.Type: GrantFiled: November 7, 2003Date of Patent: October 30, 2007Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Christopher D. Wilsey, Brian S. Hill
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Patent number: 7073246Abstract: A method of making a biosensor is provided. The biosensor includes an electrically conductive material on a base and electrode patterns formed on the base, the patterns having different feature sizes. The conductive material is partially removed from the base using broad field laser ablation so that less than 90% of the conductive material remains on the base and that the electrode pattern has an edge extending between two points. A standard deviation of the edge from a line extending between two points is less than about 6 ?m.Type: GrantFiled: June 20, 2003Date of Patent: July 11, 2006Assignee: Roche Diagnostics Operations, Inc.Inventors: Raghbir S. Bhullar, Eric R. Diebold, Brian S. Hill, Nigel A. Surridge, Douglas P. Walling
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Patent number: 6911621Abstract: A method of forming a biosensor is provided. The method includes providing a substrate and a cover including first and second surfaces, positioning a reagent on the substrate, carving a channel by laser ablation in the first surface, and coupling the first surface of the cover to the second surface. The channel includes a first portion having a first height and a second portion having a second height that is less than the first height.Type: GrantFiled: January 8, 2003Date of Patent: June 28, 2005Assignee: Roche Diagnostics CorporationInventors: Raghbir S. Bhullar, Douglas P. Walling, Brian S. Hill
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Patent number: 6866758Abstract: A biosensor is provided in accordance with the present invention. The biosensor includes an electrode support substrate, electrodes positioned on the electrode support, each electrode including a meter-contact portion and a measurement portion, and a sensor support substrate. The sensor support substrate cooperates with the electrode support substrate to define channel in alignment with the measurement portion of the electrodes. Additionally, the sensor support substrate includes opposite ends and at least one window. The at least one window is spaced-apart from the ends and in alignment with the meter-contact portion of at least one of the electrodes.Type: GrantFiled: March 21, 2002Date of Patent: March 15, 2005Assignee: Roche Diagnostics CorporationInventors: Raghbir S. Bhullar, Brian S. Hill, John T. Austera