Patents by Inventor Raghunath Anant Mashelkar

Raghunath Anant Mashelkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7501478
    Abstract: The present invention provides novel thermoprecipitating polymers of formula 1 containing novel enzyme sensitive ligands of the formula 4, processes for the preparation thereof respectively, and to the use thereof for the separation of enzymes. In formula 1 R is hydrogen or methyl, 1 is an integer in the range of from 1 to 10, m and n are either 0 or 1, x and y are integers greater than 1.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: March 10, 2009
    Assignee: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Patent number: 6867268
    Abstract: The present invention provides novel thermoprecipitating polymers of formula 1 containing novel enzyme sensitive ligands of the formula 4, processes for the preparation thereof respectively, and to the use thereof for the separation of enzymes.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: March 15, 2005
    Assignee: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Patent number: 6794467
    Abstract: The invention discloses a process for the preparation of polymeric absorbents useful for gelling organic liquids. The process comprises mixing one or more monomers with a cross-linking agent, a free radical initiator, an optional solvent, optionally in the presence of a transition metal source and subjecting the mixture so obtained to a conventional polymerisation method. The polymer is removed, crushed to obtain polymer powder, washed with solvent and dried by conventional methods to remove unreacted monomers, followed by swelling in alcohols to obtain the desired product.
    Type: Grant
    Filed: March 27, 2000
    Date of Patent: September 21, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ashish Kishor Lele, Shyni Varghese, Manohar Virupax Badiger, Raghunath Anant Mashelkar
  • Patent number: 6689836
    Abstract: The present invention relates to a process for the preparation of thermoprecipitating affinity polymers useful in the enhanced recovery of enzymes. The process comprises polymerising a monomer comprising a spacer and a co-monomer with a polymerisation initiator and a polymerisation accelerator at ambient temperature and pressure for a period ranging between 2 to 24 hours to obtain a polymer and then linking an inhibitor to pendant carboxyl groups of the spacers in the polymer to obtain an affinity polymer.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: February 10, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Publication number: 20030187172
    Abstract: The invention discloses a process for the preparation of polymeric absorbents useful for gelling organic liquids. The process comprises mixing one or more monomers with a cross-linking agent, a free radical initiator, an optional solvent, optionally in the presence of a transition metal source and subjecting the mixture so obtained to a conventional polymerisation method. The polymer is removed, crushed to obtain polymer powder, washed with solvent and dried by conventional methods to remove unreacted monomers, followed by swelling in alcohols to obtain the desired product.
    Type: Application
    Filed: March 27, 2000
    Publication date: October 2, 2003
    Inventors: Ashish Kishor Lele, Shyni Varghese, Manohar Virupax Badiger, Raghunath Anant Mashelkar
  • Patent number: 6605714
    Abstract: The present invention provides novel thermoprecipitating polymers of formula 1, processes for the preparation thereof respectively and to the use thereof for the separation of enzymes. In formula 1 R is hydrogen or methyl, and x and y are integers greater than 1.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: August 12, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Publication number: 20030027959
    Abstract: The present invention provides novel thermoprecipitating polymers of formula 1 containing novel enzyme sensitive ligands of the formula 4, processes for the preparation thereof respectively, and to the use thereof for the separation of enzymes. In formula 1 R is hydrogen or methyl, 1 is an integer in the range of from 1 to 10, m and n are either 0 or 1, x and y are integers greater than 1.
    Type: Application
    Filed: April 22, 2002
    Publication date: February 6, 2003
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Publication number: 20020143129
    Abstract: The present invention relates to a process for the preparation of thermoprecipitating affinity polymers useful in the enhanced recovery of enzymes. The process comprises polymerising a monomer comprising a spacer and a co-monomer with a polymerisation initiator and a polymerisation accelerator at ambient temperature and pressure for a period ranging between 2 to 24 hours to obtain a polymer and then linking an inhibitor to pendant carboxyl groups of the spacers in the polymer to obtain an affinity polymer.
    Type: Application
    Filed: March 11, 2002
    Publication date: October 3, 2002
    Applicant: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Publication number: 20020098567
    Abstract: The present invention provides novel thermoprecipitating polymers of formula 1 containing novel enzyme sensitive ligands of the formula 4, processes for the preparation thereof respectively, and to the use thereof for the separation of enzymes. In formula 1 R is hydrogen or methyl, 1 is an integer in the range of from 1 to 10, m and n are either 0 or 1, x and y are integers greater than 1.
    Type: Application
    Filed: November 29, 2000
    Publication date: July 25, 2002
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Patent number: 6420487
    Abstract: The present invention relates to a process for the preparation, of thermoprecipitating affinity polymers useful in the enhanced recovery of enzymes. The process comprises polymerising a monomer comprising a spacer and a co-monomer with a polymerisation initiator and a polymerisation accelerator at ambient temperature and pressure for a period ranging between 2 to 24 hours to obtain a polymer and then linking an inhibitor to pendant carboxyl groups of the spacers in the polymer to obtain an affinity polymer.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: July 16, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Patent number: 6379599
    Abstract: The invention relates to a process for the preparation of molecularly imprinted polymers useful for separation of enzymes, which comprises the steps of reacting a complex of enzyme and affinity monomer, a comonomer and a crosslinker, with a polymerization initiator and a polymerization accelerator at ambient temperature and pressure for a period ranging between 2 to 24 hrs, thereby obtaining a crosslinked polymer, crushing the cross linked polymer obtained to fine particles, adding a solvent and extracting imprinted enzyme from the polymer, obtaining the molecularly imprinted polymer, contacting the imprinted polymer with aqueous solution containing imprinted enzyme or a mixture of imprinted enzyme and other enzymes and isolating the enzyme-adsorbed polymer.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: April 30, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Alankar Arun Vaidya, Bhalchandra Shripad Lele, Mohan Gopalkrishna Kulkarni, Raghunath Anant Mashelkar
  • Patent number: 5851546
    Abstract: The present invention provides a polymer for the controlled release of a pendent chain linked active ingredient, and a process for the preparation of such a polymer for the controlled release of an active ingredient in response to pH. The process involves selecting a vinyl monomer to which the active ingredient molecule is covalently linked through a pendent group, and selecting monomers bearing catalytic groups. The active ingredient-bearing monomer and the catalytic group-containing monomer are brought in juxtaposition either by complexation or molecular imprinting, and then polymerized with a hydrophilic monomer and crosslinker under an inert atmosphere with a suitable polymerization initiator.
    Type: Grant
    Filed: March 14, 1996
    Date of Patent: December 22, 1998
    Assignee: Council of Scientific & Industrial Research
    Inventors: Raghunath Anant Mashelkar, Mohan Gopalkrishna Kulkarni, Rohini Nitin Karmalkar
  • Patent number: 5780578
    Abstract: The invention provides a polymer composed of vinyl monomers bearing imidazole, hydroxyl and carboxyl groups arranged in proximity to each other, that exhibits hydrolytic activity similar to serine proteases, and a process for its preparation. The polymer is useful for the hydrolysis of esters and amides to the corresponding alcohols and amines.
    Type: Grant
    Filed: March 14, 1996
    Date of Patent: July 14, 1998
    Assignee: Council Of Scientific & Industrial Research
    Inventors: Raghunath Anant Mashelkar, Mohan Gopalkishna Kulkarni, Rohini Nitin Karmalkar