Patents by Inventor Rahul Karnik

Rahul Karnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITING THE EXPRESSION OF MULTIPLE GENES
    Publication number: 20230374549
    Abstract: The present disclosure relates to site-specific disrupting agents for modulating, e.g., decreasing, expression of a target plurality of genes in a cell. In some embodiments, the target plurality of genes comprises pro-inflammatory genes, e.g., CXCL1, CXCL2, CXCL3, CXCL4, CXCL5, CXCL6, CXCL7, and IL-8. In some embodiments, the method comprises using a first site-specific disrupting agent that targets a first anchor sequence and a second site-specific disrupting agents that disrupts a second anchor sequence.
    Type: Application
    Filed: September 29, 2021
    Publication date: November 23, 2023
    Inventors: Lauren Marie BEECH, Jesse Jerome SMITH, Rahul KARNIK, Kendrick Alan GOSS, Adam Walter SCHEIDEGGER, Jodi Michelle KENNEDY, Jeremiah Dale FARELLI, Houda BELAGHZAL, Laura Anh NGUYEN, Charles W. O'DONNELL
  • METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
    Publication number: 20230174978
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Application
    Filed: March 18, 2022
    Publication date: June 8, 2023
    Inventors: David Arthur Berry, Rahul Karnik, Laura Gabriela Lande
  • Methods and compositions for modulating gene expression
    Patent number: 11624065
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: April 11, 2023
    Assignee: FLAGSHIP PIONEERING INNOVATIONS V, INC.
    Inventors: Laura Gabriela Lande, David Arthur Berry, Rahul Karnik
  • METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
    Publication number: 20230054672
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Application
    Filed: March 18, 2022
    Publication date: February 23, 2023
    Inventors: David Arthur Berry, Rahul Karnik, Laura Gabriela Lande
  • COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN B (APOB) GENE EXPRESSION
    Publication number: 20220288237
    Abstract: The present invention provides agents and compositions for modulating expression (e.g., enhanced or reduced expression) of an apolipoprotein B (APOB) gene by targeting an APOB expression control region and methods of use thereof for treating an APOB associated disorder, e.g., hypercholesterolemia.
    Type: Application
    Filed: March 22, 2022
    Publication date: September 15, 2022
    Applicant: Omega Therapeutics, Inc.
    Inventors: Vishwesh Ashok Patil, Jeremiah D. Farelli, Rahul Karnik, Jesse Jerome Smith, Can Sarisozen, Adam Walter Scheidegger, Barbara Bennett
  • COMPOSITIONS AND METHODS FOR MODULATING GENOMIC COMPLEX INTEGRITY INDEX
    Publication number: 20220267756
    Abstract: The present disclosure relates generally to modulation of genomic complexes via modulation (e.g., disruption) based on certain integrity index scores.
    Type: Application
    Filed: September 22, 2020
    Publication date: August 25, 2022
    Inventors: Laura Gabriela Lande, David Arthur Berry, Rahul Karnik
  • Methods and compositions for modulating gene expression
    Patent number: 11312955
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: April 26, 2022
    Assignee: FLAGSHIP PIONEERING INNOVATIONS V, INC.
    Inventors: David Arthur Berry, Rahul Karnik, Laura Gabriela Lande
  • Moving storage volumes for improved performance
    Patent number: 10817325
    Abstract: Data volumes hosted for customers in a multi-tenant environment can be moved advantageously throughout the environment to improve performance and reduce cost. A data volume can serve I/O for a virtual machine instance, and it can be advantageous for the virtual machine and the data volume to be in the same network locality, or share at least some of the same network state and interconnection. Since there is limited capacity in a network locality, data volumes not attached to virtual machines can be moved to other locations in the environment. This can include moving data volumes to other local network topologies or snapshotting data volumes and writing the snapshots to another storage service. If the data volume is again needed for I/O, the data volume can moved, allocated, or reattached as necessary.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: October 27, 2020
    Assignee: Amazon Technologies, Inc.
    Inventors: Surya Prakash Dhoolam, Mitchell Gannon Flaherty, Christopher Magee Greenwood, Gary Michael Herndon, Jr., Rahul Karnik, Sriram Venugopal
  • METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
    Publication number: 20190255106
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Application
    Filed: September 7, 2017
    Publication date: August 22, 2019
    Inventors: Laura Gabriela Lande, David Arthur Berry, Rahul Karnik
  • MOVING STORAGE VOLUMES FOR IMPROVED PERFORMANCE
    Publication number: 20190179661
    Abstract: Data volumes hosted for customers in a multi-tenant environment can be moved advantageously throughout the environment to improve performance and reduce cost. A data volume can serve I/O for a virtual machine instance, and it can be advantageous for the virtual machine and the data volume to be in the same network locality, or share at least some of the same network state and interconnection. Since there is limited capacity in a network locality, data volumes not attached to virtual machines can be moved to other locations in the environment. This can include moving data volumes to other local network topologies or snapshotting data volumes and writing the snapshots to another storage service. If the data volume is again needed for I/O, the data volume can moved, allocated, or reattached as necessary.
    Type: Application
    Filed: February 19, 2019
    Publication date: June 13, 2019
    Inventors: Surya Prakash Dhoolam, Mitchell Gannon Flaherty, Christopher Magee Greenwood, Gary Michael Herndon, JR., Rahul Karnik, Sriram Venugopal
  • Moving storage volumes for improved performance
    Patent number: 10216534
    Abstract: Data volumes hosted for customers in a multi-tenant environment can be moved advantageously throughout the environment to improve performance and reduce cost. A data volume can serve I/O for a virtual machine instance, and it can be advantageous for the virtual machine and the data volume to be in the same network locality, or share at least some of the same network state and interconnection. Since there is limited capacity in a network locality, data volumes not attached to virtual machines can be moved to other locations in the environment. This can include moving data volumes to other local network topologies or snapshotting data volumes and writing the snapshots to another storage service. If the data volume is again needed for I/O, the data volume can moved, allocated, or reattached as necessary.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: February 26, 2019
    Assignee: Amazon Technologies, Inc.
    Inventors: Surya Prakash Dhoolam, Mitchell Gannon Flaherty, Christopher Magee Greenwood, Gary Michael Herndon, Jr., Rahul Karnik, Sriram Venugopal
  • METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
    Publication number: 20190024086
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Application
    Filed: October 9, 2018
    Publication date: January 24, 2019
    Inventors: Laura Gabriela Lande, David Arthur Berry, Rahul Karnik
  • METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
    Publication number: 20180179525
    Abstract: The present disclosure provides compositions with a modulating gene expression and methods for modulating transcription.
    Type: Application
    Filed: November 22, 2017
    Publication date: June 28, 2018
    Inventors: Laura Gabriela Lande, David Arthur Berry, Rahul Karnik