Patents by Inventor Rajappa Vaidyanathan

Rajappa Vaidyanathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic process
    Patent number: 11332442
    Abstract: The invention generally relates to a process for preparing compounds, including Compound of Formula (I), useful as key intermediates in the preparation of compounds having ROR?t antagonist properties.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: May 17, 2022
    Assignees: Bristol-Myers Squibb Company, Syngene International Limited
    Inventors: William P. Gallagher, John Ryan Coombs, Carlos A. Guerrero, David Marcoux, Qing Shi, Candice Lee Joe, Sanjeewa Rupasinghe, Jason J. Zhu, Srinivas Kalidindi, Sathasivam Shunmugaraj, Moorthy Kandasamy, Siva Sankar Bondigela, Rajappa Vaidyanathan, Shankar Tulsidas Tendulkar, Sankar Kuppusamy, Francisco González-Bobes
  • SYNTHETIC PROCESS
    Publication number: 20220048859
    Abstract: The invention generally relates to a process for preparing compounds, including Compound of Formula (I), useful as key intermediates in the preparation of compounds having ROR?t antagonist properties.
    Type: Application
    Filed: August 12, 2020
    Publication date: February 17, 2022
    Inventors: William P. Gallagher, John Ryan Coombs, Carlos A. Guerrero, David Marcoux, Qing Shi, Candice Lee Joe, Sanjeewa Rupasinghe, Jason J. Zhu, Srinivas Kalidindi, Sathasivam Shunmugaraj, Moorthy Kandasamy, Siva Sankar Bondigela, Rajappa Vaidyanathan, Shankar Tulsidas Tendulkar, Sankar Kuppusamy, Francisco González-Bobes
  • Processes for the preparation of 3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide
    Patent number: 7906536
    Abstract: This invention is directed generally to processes for the preparation of compounds of Formula I: wherein R2, R3, R4, R5, X1, X2, X3, X4, X5, X6 are as defined in the specification.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: March 15, 2011
    Assignee: Pfizer Inc
    Inventors: Daniel Dukesherer, Michael Mao, Richard Vonder Embse, Gopi Yalamanchili, Rajappa Vaidyanathan, Brian Chekal, George Klemm, Ronald VanderRoest, Randy Geurink
  • PROCESSES FOR THE PREPARATION OF 3-(4-(2,4-DIFLUOROBENZYLOXY)-3-BROMO-6-METHYL-2-OXOPYRIDIN-1(2H)-YL)-N,4-DIMETHYLBENZAMIDE
    Publication number: 20080177077
    Abstract: This invention is directed generally to processes for the preparation of compounds of Formula I: wherein R2, R3, R4, R5, X1, X2, X3, X4, X5, X6 are as defined in the specification.
    Type: Application
    Filed: December 12, 2007
    Publication date: July 24, 2008
    Inventors: Daniel Dukesherer, Michael Mao, Richard Vonder Embse, Gopi Yalamanchili, Rajappa Vaidyanathan, Brian Chekal, George Klemm, Ronald VanderRoset, Randy Geurink
  • Method of synthesizing indolinone compounds
    Publication number: 20060009510
    Abstract: Disclosed are methods of preparing pyrrole compounds of formula 14 and indolinone compounds of formula 1 via a synthetic route wherein the amide sidechain on the pyrrole moiety is attached prior to pyrrole formation. The compounds 14 produced by the methods herein are useful in the synthesis of compounds of formula 1, which are useful in the treatment of abnormal cell growth, such as cancer.
    Type: Application
    Filed: July 5, 2005
    Publication date: January 12, 2006
    Inventors: Jeffrey Havens, Rajappa Vaidyanathan
  • Method for catalyzing amidation reactions
    Publication number: 20050059824
    Abstract: The invention provides a method of preparing a compound of formula 2 wherein R1 and R6 are as defined herein, by a catalytic amidation process in the presence of added carbon dioxide. The inventive methods show surprising rate enhancement relative to the corresponding uncatalyzed reaction.
    Type: Application
    Filed: September 9, 2004
    Publication date: March 17, 2005
    Inventors: Rajappa Vaidyanathan, Vikram Kalthod
  • Phosphoric acid isomerization of A 5 (10), 9 (11)—diene steroid to the corresponding 4, 9-diene steroid
    Patent number: 6797834
    Abstract: The invention is a process for the preparation of a &Dgr;4,9-steroid of formula (II) which comprises contacting a &Dgr;5(10),9(11)-steroid of formula (I) with a phosphorous containing acid.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: September 28, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventor: Rajappa Vaidyanathan
  • Phosphoric acid isomerization of A 5 (10), 9 (11) - diene steroid to the corresponding 4, 9-diene steriod
    Publication number: 20030109728
    Abstract: The invention is a process for the preparation of a &Dgr;4,9-steroid of formula (II) 1
    Type: Application
    Filed: December 10, 2002
    Publication date: June 12, 2003
    Inventor: Rajappa Vaidyanathan