Abstract: Methods of administration of vanoxerine wherein a patient, previously and successfully treated for cardiac arrhythmia with vanoxerine is prescribed a further dose for self-administration of a further dose of vanoxerine for treatment of a subsequent occurrence of cardiac arrhythmia.

Abstract: A handle for providing relative motion to a multi-lumen catheter assembly includes an elongated handle body having a longitudinal axis. The handle body has longitudinally spaced proximal and distal handle ends. An outer catheter chuck is connected to the distal handle end and is adapted to receive an outer catheter member. An inner catheter chuck is connected to the proximal handle end and is adapted to receive an inner catheter member. A handle actuator is movably connected to the handle body. The handle actuator is adapted to receive an intermediate catheter member and to move the intermediate catheter member relative to the inner and outer catheter members. The intermediate catheter is at least partially interposed between the inner and outer catheter.