Abstract: Disclosed is an improved computer architecture for generating an electronic data layout by having a user input a portion of dataset and obtaining the remaining portion of the format data from a data storage that stores reusable data for various data layouts. A master data object is configured to store “request-agnostic data,” which is typically that portion of dataset that does not differ, or is common, between various data layouts. The data that differs between various data layouts, such as the data that is specific to a form, may be considered as “request-specific data.” When a data layout generation request is received, the user may be prompted to input request-specific data, but not the request-agnostic data. The system automatically obtains the request-agnostic data from the master data object, and integrates the request-agnostic data with the request-specific data to generate the form.

Abstract: Devices and methods are provided to detect the presence of bacteria and small microorganisms, and to identify various microbial attributes rapidly.

Abstract: Devices and methods are provided to detect the presence of bacteria and small microorganisms, and to identify various microbial attributes rapidly.

Abstract: Devices and methods are provided to detect the presence of bacteria and small microorganisms, and to identify various microbial attributes rapidly.

Abstract: Devices and methods are provided to detect the presence of bacteria and small microorganisms, and to identify various microbial attributes rapidly.

Abstract: Devices and methods are provided to detect the presence of bacteria and small microorganisms, and to identify various microbial attributes rapidly.

Abstract: A fluid contamination analyzer has a sample cell containing a trapping medium capable of trapping contaminants suspended in the aqueous fluid flowing through the trapping medium, a light source for illuminating the trapping medium to cause the entrapped contaminants generate a secondary radiation indicative of the identity and quantity of the contaminants, and a photodetector for receiving the secondary radiation. The fluid contamination analyzer has a reflective shell in the form of an ellipsoid extending at least partially around the sample cell and the detector, the sample cell being positioned at one of the focal points of the ellipsoid, and the photodetector at the other point of the ellipsoid to receive the secondary radiation reflected by the reflective shell.

Abstract: A process for lyophilization or freeze-drying of a pharmaceutical product is provided and a liquid formulation suitable for lyophilization. In particular, a process for lyophilization or freeze-drying a liquid formulation that includes a protein active agent, a bulking agent and a saccharide stabilizing agent is provided. The saccharide to bulking agent ratio and the protein concentration of the formulation are important factors that affect crystallization of the bulking agent during lyophilization and storage as are some processing conditions. In one embodiment, the saccharide is a disaccharide, such as sucrose and the crystalline bulking agent is mannitol. The protein can be an antibody or a non-antibody protein.

Abstract: A fluid contamination analyzer has a sample cell containing a trapping medium capable of trapping contaminants suspended in the aqueous fluid flowing through the trapping medium, a light source for illuminating the trapping medium to cause the entrapped contaminants generate a secondary radiation indicative of the identity and quantity of the contaminants, and a photodetector for receiving the secondary radiation. The fluid contamination analyzer has a reflective shell in the form of an ellipsoid extending at least partially around the sample cell and the detector, the sample cell being positioned at one of the focal points of the ellipsoid, and the photodetector at the other point of the ellipsoid to receive the secondary radiation reflected by the reflective shell.