Patents by Inventor Rajesh Shukla

Rajesh Shukla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing D-?-methyldopa
    Patent number: 11702383
    Abstract: The present invention provides methods of synthesizing D-?-methyldopa and L-?-methyldopa.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: July 18, 2023
    Assignee: ImmunoMolecular Therapeutics, Inc.
    Inventors: Xing Fu, Rajesh Shukla
  • Synthesis of azelaic acid
    Patent number: 10358408
    Abstract: This invention concerns a method of synthesizing Azelaic Acid. Particular reference is made to providing a new synthetic process for preparing azelaic acid in large scale with high purity (e.g., >99.7% with any individual impurity not more than 0.1%), which can be used as an active pharmaceutical ingredient.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: July 23, 2019
    Assignee: POLYCARBON INDUSTRIES, INC.
    Inventors: Rajesh Thamatam, Bishwabhusan Sahoo, Rajesh Shukla
  • Synthesis of Azelaic Acid
    Publication number: 20190194115
    Abstract: This invention concerns a method of synthesizing Azelaic Acid. Particular reference is made to providing a new synthetic process for preparing azelaic acid in large scale with high purity (e.g., >99.7% with any individual impurity not more than 0.1%), which can be used as an active pharmaceutical ingredient.
    Type: Application
    Filed: December 22, 2017
    Publication date: June 27, 2019
    Applicant: PCI Synthesis, Inc.
    Inventors: Rajesh Thamatam, Bishwabhusan Sahoo, Rajesh Shukla
  • Metallofullerene contrast agents
    Patent number: 9233177
    Abstract: Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM?1 S?1 to about 300 mM?1 S?1 and forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: January 12, 2016
    Assignee: Luna Innovations Incorporated
    Inventors: Darren K. Macfarland, Robert P. Lenk, Rajesh Shukla, Kenneth L. Walker, Stephen R. Wilson, Zhiguo Zhou
  • METALLOFULLERENE CONTRAST AGENTS
    Publication number: 20110124848
    Abstract: Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM?1 S?1 to about 300 mM?1 S?1 and forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.
    Type: Application
    Filed: October 22, 2008
    Publication date: May 26, 2011
    Applicant: LUNA INNOVATIONS INCORPORATED
    Inventors: Darren K. Macfarland, Robert P. Lenk, Rajesh Shukla, Kenneth L. Walker, Stephen R. Wilson, Zhiguo Zhou
  • Enhanced relaxivity monomeric and multimeric compounds
    Publication number: 20040131551
    Abstract: Metal chelates capable of exhibiting an immobilized relativity between about 60 and 200 mM−1s−1/metal atom are useful as magnetic resonance imaging agents.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Inventors: Ramachandran S. Ranganathan, Radhakrishna Pillai, Peter C. Ratsep, Rajesh Shukla, Michael F. Tweedle, Xun Zhang
  • Enhanced relaxivity monomeric and multimeric compounds
    Patent number: 6693190
    Abstract: Metal chelates capable of exhibiting an immobilized relativity between about 60 and 200 mM−1s−1/metal atom are useful as magnetic resonance imaging agents. Additionally, a compound which is useful as a metal-chelating ligand has the following formula: wherein Q is a 4- to an 8-membered carbocyclic ring which may be fully or partially saturated; t is an integer from 2 to 16; each R group is independently hydrogen, —OH, —CH2—A, —OCH2CH(OH)CH2—A or a functional group capable of forming a conjugate with a biomolecule, provided that at least two of the R groups are selected from —CH2—A or —OCH2CH(OH)CH2—A; and A is a moiety capable of chelating a metal atom.
    Type: Grant
    Filed: May 11, 1994
    Date of Patent: February 17, 2004
    Assignee: Bracco International B.V.
    Inventors: Ramachandran S. Ranganathan, Radhakrishna Pillai, Peter C. Ratsep, Rajesh Shukla, Michael F. Tweedle, Xun Zhang