Patents by Inventor Rajwinder Lehal

Rajwinder Lehal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Combinations for Treating Cancer
    Publication number: 20240041884
    Abstract: The present invention relates to pharmaceutical combinations comprising an inhibitor of an anti-apoptotic protein and a NOTCH signaling pathway inhibitor and their use in a method for the prevention, delay of progression or treatment of cancer in a subject.
    Type: Application
    Filed: December 6, 2021
    Publication date: February 8, 2024
    Inventors: Rajwinder Lehal, Charlotte Urech, Michele Vigolo
  • New Use of Inhibitors of the Notch Signalling Pathway
    Publication number: 20230338347
    Abstract: The present invention relates to new uses and dosage regimens of inhibitors of the Notch signalling pathway such as 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine for the treatment of tumours.
    Type: Application
    Filed: September 16, 2021
    Publication date: October 26, 2023
    Inventors: Michael Bauer, Rajwinder Lehal, Maximilien Murone, Pavel Pisa, Florian Vogl, Maria Bobadilla
  • COMPOUNDS FOR THE TREATMENT OF ONCOVIRUS INDUCED CANCER AND METHODS OF USE THEREOF
    Publication number: 20220185793
    Abstract: The pesent invention relates to compounds of formula (I) pharmaceutically-acceptable salts, hydrates, solvates, or stereoisomers thereof and their use for the prevention and treatment of oncovirus induced cancer in a subject.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 16, 2022
    Inventors: Rajwinder Lehal, Guido Bold, Charlotte Urech, Vincent Zoete
  • COMPOUNDS FOR THE TREATMENT OF ONCOVIRUS INDUCED CANCER AND METHODS OF USE THEREOF
    Publication number: 20220169642
    Abstract: The present invention relates to new inhibitors of Notch signalling pathway and its use in the treatment and/or prevention of cancers.
    Type: Application
    Filed: April 9, 2020
    Publication date: June 2, 2022
    Inventors: Rajwinder Lehal, Guido Bold, Charlotte Urech, Vincent Zoete
  • METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING
    Publication number: 20210382038
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Application
    Filed: June 22, 2021
    Publication date: December 9, 2021
    Inventors: Freddy RADTKE, Rajwinder LEHAL, Viktoria REINMÜLLER, Jieping ZHU
  • Method for identifying modulators of notch signaling
    Patent number: 11085918
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: August 10, 2021
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Freddy Radtke, Rajwinder Lehal, Viktoria Reinmüller, Jieping Zhu
  • METHOD FOR IDENTIFYING MODULATORS OF NOTCH SIGNALING
    Publication number: 20190219566
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Application
    Filed: March 25, 2019
    Publication date: July 18, 2019
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Freddy RADTKE, Rajwinder LEHAL, Viktoria REINMÜLLER, Jieping ZHU
  • Method for identifying modulators of notch signaling
    Patent number: 10274481
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: April 30, 2019
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Freddy Radtke, Rajwinder Lehal, Viktoria Reinmüller, Jieping Zhu
  • Inhibitors of notch signaling pathway and use thereof in treatment of cancers
    Patent number: 10054581
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: August 21, 2018
    Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)
    Inventors: Freddy Radtke, Rajwinder Lehal, Viktoria Reinmüller, Jieping Zhu
  • INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS
    Publication number: 20180224429
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Application
    Filed: March 14, 2018
    Publication date: August 9, 2018
    Inventors: Freddy RADTKE, Rajwinder LEHAL, Viktoria REINMÜLLER, Jieping ZHU
  • INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS
    Publication number: 20160266095
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Application
    Filed: February 8, 2016
    Publication date: September 15, 2016
    Inventors: Freddy RADTKE, Rajwinder LEHAL, Viktoria REINMÜLLER, Jieping ZHU
  • Inhibitors of notch signalling pathway and use thereof in treatment of cancers
    Patent number: 9296682
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: March 29, 2016
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Freddy Radtke, Rajwinder Lehal, Viktoria Reinmuller, Jieping Zhu
  • INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS
    Publication number: 20140329867
    Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
    Type: Application
    Filed: December 21, 2012
    Publication date: November 6, 2014
    Applicant: Ecole Polytechnique Federale de Lausanne
    Inventors: Freddy Radtke, Rajwinder Lehal, Viktoria Reinmuller, Jieping Zhu