Patents by Inventor Ralf Bickel
Ralf Bickel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210172010Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.Type: ApplicationFiled: January 21, 2021Publication date: June 10, 2021Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
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Patent number: 10399260Abstract: A method for producing a composite sealing element, in particular for forming a seal at a retractable pane of a vehicle window, wherein the composite sealing element is produced from at least one extruded element portion and at least one element part formed by injection molding in a mold cavity of a mold, with the element part being molded onto an end face, bounding the mold cavity, of the extruded portion. A change in the dimensions of the composite sealing element as a result of the length of the extruded element portion differing from the nominal value is counteracted by changing the arrangement of the end face of the extruded element portion with respect to the mold cavity.Type: GrantFiled: December 16, 2015Date of Patent: September 3, 2019Assignee: CQLT SAARGUMMI TECHNOLOGIES S.À.R.L.Inventors: Michael Lorig, Ralf Bickel, Suleyman Samanci
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Patent number: 10365276Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: GrantFiled: September 28, 2017Date of Patent: July 30, 2019Assignee: ALERE TECHNOLOGIES GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20180135116Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: ApplicationFiled: February 27, 2017Publication date: May 17, 2018Applicant: CLONDIAG GMBHInventors: Eugen Emantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Publication number: 20180088115Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: ApplicationFiled: September 28, 2017Publication date: March 29, 2018Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20170355113Abstract: A method for producing a composite sealing element, in particular for forming a seal at a retractable pane of a vehicle window, wherein the composite sealing element is produced from at least one extruded element portion and at least one element part formed by injection molding in a mold cavity of a mold, with the element part being molded onto an end face, bounding the mold cavity, of the extruded portion. A change in the dimensions of the composite sealing element as a result of the length of the extruded element portion differing from the nominal value is counteracted by changing the arrangement of the end face of the extruded element portion with respect to the mold cavity.Type: ApplicationFiled: December 16, 2015Publication date: December 14, 2017Inventors: Michael LORIG, Ralf BICKEL, Suleyman SAMANCI
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Patent number: 9791441Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: GrantFiled: June 17, 2013Date of Patent: October 17, 2017Assignee: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Patent number: 9580745Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: GrantFiled: September 1, 2014Date of Patent: February 28, 2017Assignee: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Publication number: 20160237482Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.Type: ApplicationFiled: December 22, 2014Publication date: August 18, 2016Applicant: CLONDIAG GMBHInventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
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Publication number: 20150284785Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: ApplicationFiled: September 1, 2014Publication date: October 8, 2015Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Patent number: 8916348Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.Type: GrantFiled: November 6, 2006Date of Patent: December 23, 2014Assignee: Clondiag GmbHInventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
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Patent number: 8828741Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: GrantFiled: November 6, 2006Date of Patent: September 9, 2014Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Publication number: 20130295657Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: ApplicationFiled: June 17, 2013Publication date: November 7, 2013Inventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Patent number: 8467039Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: GrantFiled: October 14, 2011Date of Patent: June 18, 2013Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20120088252Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.Type: ApplicationFiled: October 14, 2011Publication date: April 12, 2012Applicant: ALERE TECHNOLOGIES GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Patent number: 8040494Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.Type: GrantFiled: November 6, 2006Date of Patent: October 18, 2011Assignee: Clondiag GmbHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20090082219Abstract: The present invention relates to devices and methods for the detection of analytes. In particular, the invention relates to methods for the qualitative and/or quantitative detection of analytes, comprising a microarray on a substrate, onto which probe molecules are immobilized on array elements, said microarray being disposed on a first surface of the device; and a detection chamber formed between the first surface including the microarray disposed thereon and a second surface, wherein the distance between the microarray and the second surface is variable, and wherein the second surface has a displacement structure.Type: ApplicationFiled: November 6, 2006Publication date: March 26, 2009Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich
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Publication number: 20090079963Abstract: The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface.Type: ApplicationFiled: November 6, 2006Publication date: March 26, 2009Applicant: CLONDIAG GMBHInventors: Eugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer
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Publication number: 20070254372Abstract: The invention relates to devices and methods for the detection of specific interactions between probe and target molecules. In particular, the invention relates to methods for the qualitative and/or quantitative detection of targets, including: introducing a sample containing targets into a reaction chamber formed between a first surface of the device and a second surface of a device, which is preferably located opposite to the first surface, wherein the distance between the first and the second surface is variable; and detecting the targets.Type: ApplicationFiled: November 6, 2006Publication date: November 1, 2007Inventors: Ralf Bickel, Alexandra Dworrak, Thomas Ellinger, Eugen Ermantraut, Torsten Schulz, Thomas Ullrich
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Publication number: 20060201622Abstract: Methods, devices and support profiles are configured to match the method and device in profiles used to attach a support section for rubber seals to automobile body parts in the shortest possible time with the minimum of tools and personnel. The methods and devices are adaptable in such a way that modifications to the geometry of the sealing section and to the contours of the body parts are accommodated without long stoppages of the assembly line. The support sections and connecting regions mold to all the contours of automobile bodyworks, in particular corner regions, and permit the attachment of various sealing regions and application of extreme detachment forces. The support section for the sealing section is attached to the support surface in one single operation. The sub-steps of said operation are carried out by an industrial robot. Adhesive is applied to the support section during its production.Type: ApplicationFiled: March 26, 2002Publication date: September 14, 2006Inventors: Ralf Sehr, Ralf Bickel