Patents by Inventor Ralf David

Ralf David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132727
    Abstract: A molecular assembly having a structural formation of amphiphilic molecules is disclosed where the amphiphilic molecules are selected from a group containing amphiphilic molecules which a) have a hydrophobic moiety and a hydrophilic moiety b) are soluble in a polar aprotic solvent and form self-organizing layer structures in the absence of the polar aprotic solvent, and c) orient molecularly in formed layer structures at an interfacial layer, or in an aqueous environment. The amphiphilic molecules in the formed layer structure are in contact with an aqueous environment. A method for coating a solid surface with a molecular assembly is also disclosed, wherein the amphiphilic molecules are dissolved in a polar aprotic solvent, and resulting solution is applied to a solid surface by spin coating.
    Type: Application
    Filed: February 23, 2022
    Publication date: April 25, 2024
    Applicant: LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E. V
    Inventors: JENS FRIEDRICHS, RALF HELBIG, LARS DAVID RENNER, TILO POMPE, JENS-UWE SOMMER, CARSTEN WERNER
  • Patent number: 11634741
    Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3?end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising a mutant enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid, wherein the mutant enzymatic activity exhibiting moiety comprises an amino acid sequence, wherein the amino acids of the amino acid sequence are D-amino acids, wherein the mutant enzymatic activity exhibiting moiety is a variant of an enzymatic activity exhibiting moiety, wherein the enzymatic activity exhibiting moiety consists of an amino acid sequence according to SEQ ID NO: 15 and wherein the amino acids of the amino acid sequence according to SEQ ID NO: 15 are D-amino acids, wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety differs from the
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: April 25, 2023
    Assignee: Aptarion biotech AG
    Inventors: Andreas Pech, Florian Jarosch, Michael Jahnz, Sven Klussmann, Ralf David
  • Patent number: 11015178
    Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3? end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: May 25, 2021
    Assignee: APTARION biotech AG
    Inventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
  • Publication number: 20180208910
    Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3? end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid.
    Type: Application
    Filed: December 5, 2017
    Publication date: July 26, 2018
    Inventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
  • Patent number: 9850471
    Abstract: The invention relates to a method of reacting one or more L-nucleotides with a first L-nucleic acid in the presence of a D-enzyme that adds the one or more L-nucleotides to the 3? end of the first L-nucleic acid.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: December 26, 2017
    Assignee: NOXXON Pharma AG
    Inventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
  • Publication number: 20160304926
    Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3?end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising a mutant enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid, wherein the mutant enzymatic activity exhibiting moiety comprises an amino acid sequence, wherein the amino acids of the amino acid sequence are D-amino acids, wherein the mutant enzymatic activity exhibiting moiety is a variant of an enzymatic activity exhibiting moiety, wherein the enzymatic activity exhibiting moiety consists of an amino acid sequence according to SEQ ID NO: 15 and wherein the amino acids of the amino acid sequence according to SEQ ID NO: 15 are D-amino acids, wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety differs from the
    Type: Application
    Filed: November 20, 2014
    Publication date: October 20, 2016
    Applicant: NOXXON Pharma AG
    Inventors: Andreas Pech, Florian Jarosch, Michael Jahnz, Sven Klussmann, Ralf David
  • Publication number: 20150337348
    Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3? end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid.
    Type: Application
    Filed: May 16, 2013
    Publication date: November 26, 2015
    Applicant: NOXXON Pharma AG
    Inventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
  • Patent number: 7547132
    Abstract: A material processing plant consists of a first screw-type machine and a second screw-type machine: The screw-type machines are connected to each other by means of a pipe elbow. An elongation compensation device is disposed between the first screw-type machine and the pipe elbow. An expansion compensation device for thermal expansion of the second screw-type machine is disposed inside the last column of the first screw-type machine which is arranged upstream of the pipe elbow.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: June 16, 2009
    Assignee: Coperion GmbH
    Inventors: Ralf Davids, Carsten Koberg, Raimund Schleicher, Ralf Riehle
  • Publication number: 20080124420
    Abstract: A material processing plant consists of a first screw-type machine and a second screw-type machine: The screw-type machines are connected to each other by means of a pipe elbow. An elongation compensation device is disposed between the first screw-type machine and the pipe elbow. An expansion compensation device for thermal expansion of the second screw-type machine is disposed inside the last column of the first screw-type machine which is arranged upstream of the pipe elbow.
    Type: Application
    Filed: November 2, 2007
    Publication date: May 29, 2008
    Inventors: Ralf Davids, Carsten Koberg, Raimund Schleicher, Ralf Riehle
  • Publication number: 20030140510
    Abstract: An improved vehicle compass calibration obtains magnetic field data measurements from magnetic field sensors mounted in a vehicle. The magnetic field data measurements are stored in memory and, when a sufficient set of data measurements is stored, a calibration calculation attempt is carried out. When a predetermined vehicle accessory that produces a magnetic disturbance is activated, the storage of magnetic field data in memory is interrupted to disable the ongoing collection of data for use in a subsequent calibration calculation while the accessory remains activated.
    Type: Application
    Filed: January 31, 2002
    Publication date: July 31, 2003
    Applicant: Siemens VDO Automotive Corporation
    Inventors: Ralf David Woods, Larrie Gould, Gregory Sullivan
  • Patent number: 4297917
    Abstract: A driving gear assembly for a double helix extruder. The assembly includes a multiple power path from a transmission gear to produce synchronism in the extruder helix shafts. The structure of the gearing enables a simple adjustment of the proper mesh of the extruder helices when mounting the gearing by mere disengagement and re-engagement of a (normally not disengageable) tooth coupling.
    Type: Grant
    Filed: September 18, 1979
    Date of Patent: November 3, 1981
    Assignees: Werner & Pfleiderer, Zahnraderfabrik Renk Aktiengesellschaft
    Inventors: Erwin Bauer, Ralf Davids, Gerhard Gotz, Hilmar Jussen, Heinrich Arndt, Louis Kummel, Rudolf Morhart, Erich Pollak-Banda