Patents by Inventor Ralf David
Ralf David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240132727Abstract: A molecular assembly having a structural formation of amphiphilic molecules is disclosed where the amphiphilic molecules are selected from a group containing amphiphilic molecules which a) have a hydrophobic moiety and a hydrophilic moiety b) are soluble in a polar aprotic solvent and form self-organizing layer structures in the absence of the polar aprotic solvent, and c) orient molecularly in formed layer structures at an interfacial layer, or in an aqueous environment. The amphiphilic molecules in the formed layer structure are in contact with an aqueous environment. A method for coating a solid surface with a molecular assembly is also disclosed, wherein the amphiphilic molecules are dissolved in a polar aprotic solvent, and resulting solution is applied to a solid surface by spin coating.Type: ApplicationFiled: February 23, 2022Publication date: April 25, 2024Applicant: LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E. VInventors: JENS FRIEDRICHS, RALF HELBIG, LARS DAVID RENNER, TILO POMPE, JENS-UWE SOMMER, CARSTEN WERNER
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Patent number: 11634741Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3?end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising a mutant enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid, wherein the mutant enzymatic activity exhibiting moiety comprises an amino acid sequence, wherein the amino acids of the amino acid sequence are D-amino acids, wherein the mutant enzymatic activity exhibiting moiety is a variant of an enzymatic activity exhibiting moiety, wherein the enzymatic activity exhibiting moiety consists of an amino acid sequence according to SEQ ID NO: 15 and wherein the amino acids of the amino acid sequence according to SEQ ID NO: 15 are D-amino acids, wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety differs from theType: GrantFiled: November 20, 2014Date of Patent: April 25, 2023Assignee: Aptarion biotech AGInventors: Andreas Pech, Florian Jarosch, Michael Jahnz, Sven Klussmann, Ralf David
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Patent number: 11015178Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3? end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid.Type: GrantFiled: December 5, 2017Date of Patent: May 25, 2021Assignee: APTARION biotech AGInventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
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Publication number: 20180208910Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3? end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid.Type: ApplicationFiled: December 5, 2017Publication date: July 26, 2018Inventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
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Patent number: 9850471Abstract: The invention relates to a method of reacting one or more L-nucleotides with a first L-nucleic acid in the presence of a D-enzyme that adds the one or more L-nucleotides to the 3? end of the first L-nucleic acid.Type: GrantFiled: May 16, 2013Date of Patent: December 26, 2017Assignee: NOXXON Pharma AGInventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
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Publication number: 20160304926Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3?end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising a mutant enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid, wherein the mutant enzymatic activity exhibiting moiety comprises an amino acid sequence, wherein the amino acids of the amino acid sequence are D-amino acids, wherein the mutant enzymatic activity exhibiting moiety is a variant of an enzymatic activity exhibiting moiety, wherein the enzymatic activity exhibiting moiety consists of an amino acid sequence according to SEQ ID NO: 15 and wherein the amino acids of the amino acid sequence according to SEQ ID NO: 15 are D-amino acids, wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety differs from theType: ApplicationFiled: November 20, 2014Publication date: October 20, 2016Applicant: NOXXON Pharma AGInventors: Andreas Pech, Florian Jarosch, Michael Jahnz, Sven Klussmann, Ralf David
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Publication number: 20150337348Abstract: The present invention is related to a method for adding one or more L-nucleotides to the 3? end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising an enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3? end of the first L-nucleic acid.Type: ApplicationFiled: May 16, 2013Publication date: November 26, 2015Applicant: NOXXON Pharma AGInventors: Andreas Pech, Ralf David, Florian Jarosch, Michael Jahnz, Sven Klussmann
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Patent number: 7547132Abstract: A material processing plant consists of a first screw-type machine and a second screw-type machine: The screw-type machines are connected to each other by means of a pipe elbow. An elongation compensation device is disposed between the first screw-type machine and the pipe elbow. An expansion compensation device for thermal expansion of the second screw-type machine is disposed inside the last column of the first screw-type machine which is arranged upstream of the pipe elbow.Type: GrantFiled: November 2, 2007Date of Patent: June 16, 2009Assignee: Coperion GmbHInventors: Ralf Davids, Carsten Koberg, Raimund Schleicher, Ralf Riehle
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Publication number: 20080124420Abstract: A material processing plant consists of a first screw-type machine and a second screw-type machine: The screw-type machines are connected to each other by means of a pipe elbow. An elongation compensation device is disposed between the first screw-type machine and the pipe elbow. An expansion compensation device for thermal expansion of the second screw-type machine is disposed inside the last column of the first screw-type machine which is arranged upstream of the pipe elbow.Type: ApplicationFiled: November 2, 2007Publication date: May 29, 2008Inventors: Ralf Davids, Carsten Koberg, Raimund Schleicher, Ralf Riehle
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Publication number: 20030140510Abstract: An improved vehicle compass calibration obtains magnetic field data measurements from magnetic field sensors mounted in a vehicle. The magnetic field data measurements are stored in memory and, when a sufficient set of data measurements is stored, a calibration calculation attempt is carried out. When a predetermined vehicle accessory that produces a magnetic disturbance is activated, the storage of magnetic field data in memory is interrupted to disable the ongoing collection of data for use in a subsequent calibration calculation while the accessory remains activated.Type: ApplicationFiled: January 31, 2002Publication date: July 31, 2003Applicant: Siemens VDO Automotive CorporationInventors: Ralf David Woods, Larrie Gould, Gregory Sullivan
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Patent number: 4297917Abstract: A driving gear assembly for a double helix extruder. The assembly includes a multiple power path from a transmission gear to produce synchronism in the extruder helix shafts. The structure of the gearing enables a simple adjustment of the proper mesh of the extruder helices when mounting the gearing by mere disengagement and re-engagement of a (normally not disengageable) tooth coupling.Type: GrantFiled: September 18, 1979Date of Patent: November 3, 1981Assignees: Werner & Pfleiderer, Zahnraderfabrik Renk AktiengesellschaftInventors: Erwin Bauer, Ralf Davids, Gerhard Gotz, Hilmar Jussen, Heinrich Arndt, Louis Kummel, Rudolf Morhart, Erich Pollak-Banda