Patents by Inventor Ralf Gessler

Ralf Gessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7806853
    Abstract: The invention concerns an array and a method for dosing a hormone regulating the blood glucose, especially insulin, of a diabetic patient.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: October 5, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Uwe Wittmann, Helmut Rinne, Ralf Gessler, Hans-Joerg Pfleiderer
  • Publication number: 20090254024
    Abstract: The invention concerns an array and a method for dosing a hormone regulating the blood glucose, especially insulin, of a diabetic patient (10). In order to improve the administration of the hormone, the invention provides the following characteristic combination: a) a measuring device (16) to detect measured values correlatable with blood sugar; b) a controlling means (12) comprising a controller (44) and a hormone dosing device (46) for supplying a hormone dosage; c) a pilot control device (14) acting on the hormone fine dosage controlling means (12) for performing a coarse pre-control in accordance with at least one influence variable that influences blood glucose.
    Type: Application
    Filed: May 22, 2009
    Publication date: October 8, 2009
    Inventors: Uwe Wittmann, Helmut Rinne, Ralf Gessler, Hans-Joerg Pfleiderer
  • Patent number: 7556613
    Abstract: The invention concerns an array and a method for dosing a hormone regulating the blood glucose, especially insulin of a diabetic patient (10). In order to improve the administration of the hormone, the invention provides the following characteristic combination: a) a measuring device (16) to detect measured values correlatable with blood sugar; b) a controlling means (12) comprising a controller (44) and a hormone dosing device (46) for supplying a hormone dosage; c) a pilot control device (14) acting on the hormone fine dosage controlling means (12) for performing a coarse pre-control in accordance with at least one influence variable that influences blood glucose.
    Type: Grant
    Filed: January 20, 2001
    Date of Patent: July 7, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Uwe Wittmann, Helmut Rinne, Ralf Gessler, Hans-Joerg Pfleiderer
  • Patent number: 7169600
    Abstract: The invention concerns an arrangement for determining the concentration of glucose in a tissue fluid. In the microdialysis technology used for this purpose, perfusate-containing glucose is transported in intermittent delivery pulses through a microdialysis probe inserted into the tissue fluid and dialysate obtained in this process is passed to a measuring cell to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the tissue fluid by means of a control device in accordance with a command variable derived from the measurement signals of the measuring cell. When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the tissue fluid.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: January 30, 2007
    Assignee: Roche Diagnostics GmbH
    Inventors: Udo Hoss, Hans-Joerg Pfleiderer, Ralf Gessler, Hans-Ulrich Zieten, Rolf Fussgaenger
  • Patent number: 6852500
    Abstract: The invention concerns a method and an arrangement for determining the concentration of glucose in a body fluid. In the microdialysis technology used for this purpose, perfusate containing glucose is transported in intermittent delivery pulses through a microdialysis probe (10) inserted into the body fluid and dialysate obtained in this process is passed to a measuring cell (16) to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the body fluid by means of a control device (18, 20) in accordance with a command variable derived from the measurement signals of the measuring cell (16). When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the body fluid.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: February 8, 2005
    Assignee: Roche Diagnostics GmbH
    Inventors: Udo Hoss, Hans-Joerg Pfleiderer, Ralf Gessler, Hans-Ulrich Zieten, Rolf Fussgaenger
  • Publication number: 20040191848
    Abstract: The invention concerns an arrangement for determining the concentration of glucose in a tissue fluid. In the microdialysis technology used for this purpose, perfusate-containing glucose is transported in intermittent delivery pulses through a microdialysis probe inserted into the tissue fluid and dialysate obtained in this process is passed to a measuring cell to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the tissue fluid by means of a control device in accordance with a command variable derived from the measurement signals of the measuring cell. When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the tissue fluid.
    Type: Application
    Filed: February 19, 2004
    Publication date: September 30, 2004
    Inventors: Udo Hoss, Hans-Joerg Pfleiderer, Ralf Gessler, Hans-Ulrich Zieten, Rolf Fussgaenger
  • Publication number: 20030104982
    Abstract: The invention concerns an array and a method for dosing a hormone regulating the blood glucose, especially insulin of a diabetic patient (10). In order to improve the administration of the hormone, the invention provides the following characteristic combination: a) a measuring device (16) to detect measured values correlatable with blood sugar; b) a controlling means (12) comprising a controller (44) and a hormone dosing device (46) for supplying a hormone dosage; c) a pilot control device (14) acting on the hormone fine dosage controlling means (12) for performing a coarse pre-control in accordance with at least one influence variable that influences blood glucose.
    Type: Application
    Filed: November 18, 2002
    Publication date: June 5, 2003
    Inventors: Uwe Wittmann, Helmut Rinne, Ralf Gessler, Hans-Joerg Pfleiderer