Patents by Inventor Ralf Kraus

Ralf Kraus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11988544
    Abstract: The invention relates to a method for weighing pharmaceutical containers (10) nested in a carrier (11), in which at least one of the nested containers (10) is weighed by means of a weighing device (1), wherein a relative movement between the at least one pharmaceutical container (10) and the carrier (11) is brought about in order to release the pharmaceutical containers (10) from the carrier (11) in order to increase the weighing accuracy.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: May 21, 2024
    Assignees: Syntegon Technology GmbH, Syntegon Packaging Systems AG, Syntegon Packaging Technology GmbH
    Inventors: Philipp Roth, Ulrich Krauß, Klaus Ullherr, Tim Fleckenstein, Rolf Barthelmess, Martin Maerz, Thomas Beck, Ralf Riebeling, Heiko Wild, Joachim Radtke, Jochen Peters, Oliver Gerundt, Harald Ott, Olaf Eistert, Frank Scholl, Herbert Schaffert, Jochen Lautenschlager, Paul Mehringer, Faruk Civelek
  • Publication number: 20230251253
    Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
    Type: Application
    Filed: April 14, 2023
    Publication date: August 10, 2023
    Applicants: Roche Diagnostics Operations, Inc., Hitachi High-Tech Corporation
    Inventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
  • Patent number: 11703504
    Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: July 18, 2023
    Assignees: ROCHE DIAGNOSTICS OPERATIONS, INC., HITACHI HIGH-TECH CORPORATION
    Inventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
  • Publication number: 20210349112
    Abstract: There is provided an automatic analyzer that can reduce a cleaning agent used for cleaning a puddle configured to stir a reagent including a fine particle. An automatic analyzer including a reagent container configured to accommodate a reagent including a fine particle, a puddle configured to stir the reagent, and a cleaning unit configured to immerse the puddle in a cleaning vessel reserving a cleaning agent. The automatic analyzer further includes a determining unit configured to determine whether to totally replace the cleaning agent based on a score computed using a number of times of cleaning the puddle having stirred the reagent in the cleaning unit and a remaining amount of the reagent. When the determining unit determines that the cleaning agent is totally replaced, the cleaning unit displays, on a screen, a notification of total replacement of the cleaning agent, or recommendation of the total replacement.
    Type: Application
    Filed: January 20, 2020
    Publication date: November 11, 2021
    Inventors: Koshin HAMASAKI, Eiichiro TAKADA, Shigeki MATSUBARA, Tatsuya FUKUGAKI, Stefan KOBEL, Ralf KRAUS
  • Publication number: 20200003768
    Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
    Type: Application
    Filed: September 5, 2019
    Publication date: January 2, 2020
    Applicants: Roche Diagnostics Operations, Inc., Hitachi High-Technologies Corporation
    Inventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro y Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
  • Patent number: 10422797
    Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: September 24, 2019
    Assignees: ROCHE DIAGNOSTICS OPERATIONS, INC., HITACHI HIGH-TECHNOLOGIES CORPORATION
    Inventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
  • Publication number: 20160097765
    Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
    Type: Application
    Filed: December 14, 2015
    Publication date: April 7, 2016
    Inventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Kenichi Takahashi
  • Patent number: 7980903
    Abstract: An installation switch has an insulating housing and a terminal connecting arrangement for clamping a connecting conductor having an annular terminal shoe. The terminal connecting arrangement includes a terminal socket having an interior disposed between an insertion opening for receiving the terminal shoe and an access opening and a terminal screw having a screw head and a screw shank disposed in the interior of the terminal socket, the screw being actuatable in a longitudinal direction within the interior of the terminal socket between an open state and a clamped state. The arrangement further includes a connection plate having a screw hole with interior threads for threadably engaging the terminal screw when in the clamped state and a retaining device preventing the terminal screw from being removed from the terminal socket when in the open state.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: July 19, 2011
    Assignee: ABB AG
    Inventors: Matthias Bitz, Ralf Kraus, Klaus-Peter Eppe
  • Publication number: 20100227513
    Abstract: An installation switch has an insulating housing and a terminal connecting arrangement for clamping a connecting conductor having an annular terminal shoe. The terminal connecting arrangement includes a terminal socket having an interior disposed between an insertion opening for receiving the terminal shoe and an access opening and a terminal screw having a screw head and a screw shank disposed in the interior of the terminal socket, the screw being actuatable in a longitudinal direction within the interior of the terminal socket between an open state and a clamped state. The arrangement further includes a connection plate having a screw hole with interior threads for threadably engaging the terminal screw when in the clamped state and a retaining device preventing the terminal screw from being removed from the terminal socket when in the open state.
    Type: Application
    Filed: March 11, 2010
    Publication date: September 9, 2010
    Applicant: ABB AG
    Inventors: Matthias Bitz, Ralf Kraus, Klaus-Peter Eppe
  • Patent number: 7704105
    Abstract: An installation switch having a housing and a connecting arrangement for a conductor having a terminal shoe. The connecting arrangement includes a socket having an interior, an insertion opening, and an access opening, and a screw having a screw head and a screw shank disposed in the interior of the socket. The screw is actuatable longitudinally between an open and a clamped state. The arrangement further includes a connection plate having a screw hole with threads for threadably engaging the screw when in the clamped state, and a retaining device preventing the screw from being removed when in the open state. The arrangement is configured so that the open state allows the shoe to be inserted into the insertion opening, the clamped state provides the screw being engaged with the shoe, and access to the screw is provided via the access opening of the socket to actuate the screw.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: April 27, 2010
    Assignee: ABB AG
    Inventors: Matthias Bitz, Ralf Kraus, Klaus-Peter Eppe
  • Publication number: 20090053927
    Abstract: An installation switch having a housing and a connecting arrangement for a conductor having a terminal shoe. The connecting arrangement includes a socket having an interior, an insertion opening, and an access opening, and a screw having a screw head and a screw shank disposed in the interior of the socket. The screw is actuatable longitudinally between an open and a clamped state. The arrangement further includes a connection plate having a screw hole with threads for threadably engaging the screw when in the clamped state, and a retaining device preventing the screw from being removed when in the open state. The arrangement is configured so that the open state allows the shoe to be inserted into the insertion opening, the clamped state provides the screw being engaged with the shoe, and access to the screw is provided via the access opening of the socket to actuate the screw.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 26, 2009
    Applicant: ABB AG
    Inventors: Matthias Bitz, Ralf Kraus, Klaus-Peter Eppe