Patents by Inventor Ralf R. H. Lotz

Ralf R. H. Lotz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS
    Publication number: 20080249089
    Abstract: The present invention relates to substituted xanthines of general formula wherein R1 to R3 are defined as in claims 1 to 16, the tautomers, the stereoisomers, the mixtures, the prodrugs thereof and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
    Type: Application
    Filed: June 20, 2008
    Publication date: October 9, 2008
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Matthias Eckhardt, Michael Mark, Roland Maier, Ralf R.H. Lotz, Mohammad Tadayyon
  • 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
    Patent number: 7407955
    Abstract: The present invention relates to substituted xanthines of general formula wherein R1 to R3 are defined as in claims 1 to 16, the tautomers, the stereoisomers, the mixtures, the prodrugs thereof and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: August 5, 2008
    Assignee: Boehringer Ingelheim Pharma GmbH & Co., KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Matthias Eckhardt, Michael Mark, Roland Maier, Ralf R. H. Lotz, Mohammad Tadayyon
  • Indolinones substituted by heterocycles, the preparation thereof and their use as medicaments
    Patent number: 7148249
    Abstract: The present invention relates to heterocyclically substituted indolinones of general formula wherein R1 to R5 and X are defined as in claim 1, the tautomers, the diastereomers, the enantiomers, the mixtures thereof, the prodrugs thereof and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases and cyclin/CDK complexes and on the proliferation of endothelial cells and various tumour cells, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: December 12, 2006
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Joerg Kley, Frank Hilberg, Armin Heckel, Gerald Juergen Roth, Thorsten Lehmann-Lintz, Ralf R. H. Lotz, Ulrike Tontsch-Grunt, Jacobus C. A. Van Meel
  • New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture
    Publication number: 20040242572
    Abstract: The present invention relates to carboxamide compounds of general formula I 1
    Type: Application
    Filed: August 22, 2003
    Publication date: December 2, 2004
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Dirk Stenkamp, Martin Lenter, Heike-Andrea Wieland, Klaus Rudolf, Stephan George Mueller, Ralf R.H. Lotz, Kirsten Arndt, Philipp Lustenberger, Thorsten Lehmann-Lintz
  • Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
    Publication number: 20040209865
    Abstract: The present invention relates to alkyne compounds of general formula I 1
    Type: Application
    Filed: October 30, 2003
    Publication date: October 21, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Dirk Stenkamp, Stephan Georg Mueller, Gerald Juergen Roth, Thorsten Lehmann-Lintz, Klaus Rudolf, Philipp Lustenberger, Kirsten Arndt, Ralf R.H. Lotz, Martin Lenter
  • Xanthine derivatives, their preparation and their use in pharmaceutical compositions
    Publication number: 20040166125
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: August 7, 2003
    Publication date: August 26, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Matthias Eckhardt, Michael Mark, Roland Maier, Ralf R. H. Lotz
  • Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
    Publication number: 20040138214
    Abstract: Disclosed are substituted xanthines of general formula 1
    Type: Application
    Filed: October 28, 2003
    Publication date: July 15, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Matthias Eckhardt, Roland Maier, Michael Mark, Mohammad Tadayyon, Ralf R. H. Lotz
  • New purine derivatives, the preparation thereof and their use as pharmaceutical compositions
    Publication number: 20040122228
    Abstract: The invention relates to new purine derivatives of general formula 1
    Type: Application
    Filed: August 4, 2003
    Publication date: June 24, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Roland Maier, Frank Himmelsbach, Matthias Eckhardt, Elke Langkopf, Michael Mark, Ralf R. H. Lotz
  • 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
    Publication number: 20040097510
    Abstract: The present invention relates to substituted xanthines of general formula 1
    Type: Application
    Filed: August 12, 2003
    Publication date: May 20, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Frank Himmelsbach, Elke Langkopf, Matthias Eckhardt, Michael Mark, Roland Maier, Ralf R.H. Lotz, Mohammad Tadayyon
  • Xanthine derivatives,production and use thereof as medicament
    Publication number: 20040077645
    Abstract: The present invention relates to substituted xanthines of general formula 1
    Type: Application
    Filed: December 5, 2003
    Publication date: April 22, 2004
    Inventors: Frank Himmelsbach, Michael Mark, Matthias Eckhardt, Elke Langkopf, Roland Maier, Ralf R H Lotz