Patents by Inventor Ralph E. Levy

Ralph E. Levy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7498309
    Abstract: Disclosed are pharmaceutical compositions suitable for oral administration of bioactive peptides. Particularly, the pharmaceutical compositions comprise peptides formulated as suspensions stabilized with a dispersing agent. The compositions may be encapsulated in capsules for oral administration. The compositions show improved dissolution characteristics, which are believed to make them suitable for use in the treatment of gastrointestinal disorders.
    Type: Grant
    Filed: November 29, 2004
    Date of Patent: March 3, 2009
    Assignee: Sangstat Medical Corporation
    Inventor: Ralph E. Levy
  • Patent number: 6254885
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of admiration in hard capsules are provided. In the subject formations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formalations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: July 3, 2001
    Assignees: SangStat Medical Corporation, The University of North Carolina at Chapel Hill
    Inventors: Moo J. Cho, Ralph E. Levy, Philippe J. Pouletty
  • Patent number: 5962019
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in both liquid and hard capsule form are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formulations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: October 5, 1999
    Assignees: SangStat Medical Corporation, University of North Carolina at Chapel Hill
    Inventors: Moo J. Cho, Ralph E. Levy, Philippe J. Pouletty
  • Patent number: 5766629
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in hard capsules are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formulations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
    Type: Grant
    Filed: March 21, 1996
    Date of Patent: June 16, 1998
    Assignee: SangStat Medical Corporation
    Inventors: Moo J. Cho, Ralph E. Levy, Philippe J. Pouletty