Abstract: The invention relates to carbon-13 enriched fullerene and carbon nanotube (CNT) compositions for improved magnetic resonance imaging (“MRI”). The invention also relates to a dynamic nuclear polarization (DNP) method of MRI utilizing the carbon-13 enriched fullerene and CNTs of the invention.

Abstract: A method for increasing sensitivity and/or specificity of a magnetic resonance spectroscopy imaging technique for detecting a neurodegenerative disease is provided. The method includes acquiring magnetic resonance spectroscopy data from the brain of a subject, while suppressing certain metabolites in the spectrum via a data acquisition protocol, to improve quantification accuracy for the remaining metabolites, and quantifying a metabolite concentration or a metabolite concentration ratio from the spectral data as an indicator of the neurodegenerative disease.

Abstract: A system and method for imaging is presented that includes exciting water-exchangeable spins in oxygen bearable molecules in a ROI having a change in oxygen status. A proton transfer within the ROI from exchangeable protons within water is detected such that changes in oxygen levels across the ROI are distinguishable.