Abstract: A locking clamp assembly that permits movement in one direction and prevents movement in a second direction to eliminate unintentional locking clamp assembly loosening encountered during normal operation. The locking clamp assembly includes a clamp head with a threaded portion and at least one retaining slot traversing the threaded portion, a clamp housing adapted to threadedly received the clamp head, and a locking pin that is operatively mounted on the clamp housing and is positioned adjacent to the retaining slot. When the locking clamp assembly is engaged, the locking pin is adapted to interact with at least one retaining slot to prevent the locking clamp assembly from movement in a first direction and for actuation by a retaining slot to enable movement of the locking clamp assembly in a second direction. There is also an engage means for the locking pin to selectively engaged or disengaged the locking clamp assembly.