Patents by Inventor Ralph L. Brattsand

Ralph L. Brattsand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5215979
    Abstract: The invention refers to compounds having activity against inflammatory, allergic, and dermatological conditions. The compounds are characterized by the formula ##STR1## or a stereoisomeric component thereof, in which formula R.sub.1 is selected from a straight or branched hydrocarbon chain having 1-4 carbon atoms.The invention also refers to processes for the preparation of these compounds, pharmaceutical preparations containing one of the compounds and a method for the treatment of inflammatory, allergic, muscoskeletal and dermatological conditions.
    Type: Grant
    Filed: October 16, 1991
    Date of Patent: June 1, 1993
    Assignee: Aktiebolaget Draco
    Inventors: Paul H. Andersson, Per T. Andersson, Bengt I. Axelsson, Ralph L. Brattsand, Bror A. Thalen, Jan W. Trofast
  • Patent number: 4820700
    Abstract: The invention refers to compounds having anti-inflammatory activity, characterized by the formula ##STR1## in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents in the carbon atom at position 20, in which formula the 1,2 position is saturated or is a double bond,X.sub.1 is hydrogen, fluorine, chlorine or bromine,X.sub.2 is hydrogen, fluorine, chlorine or bromine,R.sub.1 is hydrogen or methyl,R.sub.2 is a straight or branched hydrocarbon chain having 1-10 carbon atoms andR.sub.3 is hydrogen or a straight or branched chain alkyl group having 1-12 carbon atoms, a lower alkyl group substituted by 1-5 halogen atoms or an unsubstituted or substituted phenyl or benzyl group,provided that when R.sub.1 is methyl R.sub.2 is a hydrocarbon chain having 2-10 carbon atoms.
    Type: Grant
    Filed: January 5, 1987
    Date of Patent: April 11, 1989
    Assignee: Aktiebolaget Draco
    Inventors: Ralph L. Brattsand, Bror A. Thalen
  • Patent number: 4693999
    Abstract: Pharmaceutical composition for administration primarily to the respiratory tract when treating and controlling anti-inflammatory conditions comprising liposomes in combination with a compound of the formula ##STR1## and R.sup.1 is a saturated or unsaturated, straight or branched alkyl group with 11-19 carbon atoms and R is H, --COCH.sub.3, --COC.sub.2 H.sub.5, --CO(CH.sub.2).sub.2 CH.sub.3 or --CO(CH.sub.2).sub.3 CH.sub.3.The invention also refers to the compounds of the formula I per se processes for preparation of these compounds and to a method for the treatment of inflammatory conditions.
    Type: Grant
    Filed: July 3, 1985
    Date of Patent: September 15, 1987
    Assignee: Aktiebolaget Draco
    Inventors: Bengt I. Axelsson, Ralph L. Brattsand, Carl M. O. Dahlback, Leif A. Kallstrom, Jan W. Trofast
  • Patent number: 4404200
    Abstract: The invention refers to compounds having anti-inflammatory activity, characterized by the formula ##STR1## in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents at the carbon atom in position 22, in which formula A is n-propyl or n-butyl and Z is hydroxyl or hydroxyl esterified with a fatty acid with a straight or branched hydrocarbon chain having 1-5 carbon atoms.The invention also refers to a process for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment and control of inflammatory conditions.
    Type: Grant
    Filed: November 17, 1981
    Date of Patent: September 13, 1983
    Assignee: Aktiebolaget Draco
    Inventors: Bror A. Thalen, Ralph L. Brattsand