Abstract: Embodiments for managing data in a large-scale computer network coupling one or more client computer to a server and having multiple clusters having respective applications, by: encoding web-based data of services to a web browser of a client computer; forwarding requests from the web browser to a cluster access subsystem that wraps the requests in a security protocol interaction that preserves an identity of a user of the client computer; deploying to deploy the applications using an application descriptor for each application of the deployed applications; and storing data about how each application can be accessed through service endpoints including a network address and port identifier for access by queries by any other component, application, or service in the network.

Abstract: The present disclosure is directed to the modulation of in variant Natural Killer T Cells (iNKT Cells) using a Th2-polarizing iNKT Cell agonist, such as an ?-galactosylceramide, synthetic glycolipid OCH, or C20:2 ?-galactosylceramide analog. Said Th2-polarizing iNKT Cell agonists are used the treatment of sepsis and/or apoptosis in a subject. A method of diagnosing early stage sepsis in a subject by measuring a ratio of circulating iNKT cells relative to total circulating T cells in a subject is also disclosed.

Abstract: A system comprising a database comprising authorization data and clearing data from transactions carried out at a plurality of merchants, the authorization data comprising a plurality of transaction records, each transaction record comprising a payment card identifier, a merchant identifier, a transaction identifier, a time/date, and an authorization transaction amount; the clearing data comprising a plurality of transaction identifiers and a corresponding plurality of clearing transaction amounts. The system also comprises a gratuity calculation component in communication with the database.