Patents by Inventor Rama K. Narra

Rama K. Narra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6730286
    Abstract: A process for preparing a sterile injectable suspension of radiolabeled macroaggregated serum albumin suitable for use in scanning a mammalian patient consisting of: 1) purifying serum albumin with a saline solution; 2) buffering the purified serum albumin; 3) adding stannous halide in HCl solution to the buffered mixture to obtain a reaction mixture; 4) gradually heating and cooling the reaction mixture to form macroaggregate particles; 5) separating the macroaggregates from the reaction mixture; 6) suspending the macroaggregates in sterile water for injection; 7) adding purified serum albumin; 8) lyophilizing the suspension; and 9) reconstituting the radiolabeled lyophilizate with 99mTc. The invention also includes a process for preparing a stable, sterile lyophilizate of macroaggregate particles of human serum albumin consisting of steps 1-7.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: May 4, 2004
    Assignee: Bracco Diagnostics, Inc.
    Inventors: Ernst Schramm, Rama K. Narra, Bruce Kuczynski, Julius P. Zodda
  • Publication number: 20020182148
    Abstract: A process for preparing a sterile injectable suspension of radiolabeled macroaggregated serum albumin suitable for use in scanning a mammalian patient consisting of:
    Type: Application
    Filed: February 28, 2001
    Publication date: December 5, 2002
    Inventors: Ernst Schramm, Rama K. Narra, Bruce Kuczynski, Julius P. Zodda
  • Patent number: 4342724
    Abstract: A container having a container tube with a central tube chamber and apertures at both ends with a resilient plug over each aperture, a weir extending into the central tube chamber.The container is useful for drawing blood and labeling it with Tc-99.The container is sterile and sealed at less than atmospheric pressure inside.
    Type: Grant
    Filed: August 21, 1980
    Date of Patent: August 3, 1982
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Rama K. Narra
  • Patent number: 4342740
    Abstract: The labeling of red blood cells with technetium-99m using a stannous reducing agent is facilitated by the addition of an oxidizing agent along with the radioactive pertechnetate ion.
    Type: Grant
    Filed: August 18, 1980
    Date of Patent: August 3, 1982
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Rama K. Narra, Bruce L. Kuczynski