Patents by Inventor Ramji T. Venkatasubramanian
Ramji T. Venkatasubramanian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230088407Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.Type: ApplicationFiled: November 14, 2022Publication date: March 23, 2023Inventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Cyril J. Schweich, Todd J. Mortier
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Patent number: 11497600Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.Type: GrantFiled: October 1, 2019Date of Patent: November 15, 2022Assignee: CAISSON INTERVENTIONAL, LLCInventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Cyril J. Schweich, Jr., Todd J. Mortier
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Patent number: 11166816Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The stent is formed of a plurality of struts. A cuff is coupled to the stent. The cuff has one or more features configured to reduce abrasion and/or perivalvular leakage.Type: GrantFiled: October 10, 2018Date of Patent: November 9, 2021Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Julia A. Schraut, Peter N. Braido, Ramji T. Venkatasubramanian, Aditee Kurane, Mina S. Fahim, Jaishankar Kutty
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Patent number: 10603167Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae.Type: GrantFiled: August 24, 2017Date of Patent: March 31, 2020Assignee: Caisson Interventional, LLCInventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Andrew T. Forsberg, Cyril J. Schweich, Jr., Todd J. Mortier, Erik O. Martz, Douglas J. Krone
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Patent number: 10582882Abstract: A system for detecting the dimensions and geometry of a native valve annulus for trans-catheter valve implantation includes a compliant balloon and a shaft within the balloon. One or more drive electrodes may be affixed to a surface of the balloon, and one or more sense electrodes may be affixed to the shaft. After insertion of the balloon into the native valve annulus, the drive electrodes may be energized with a predetermined voltage. Using a trained statistical model and the voltages measured at the sense electrodes, initial estimates of the cross-section of the valve annulus may be obtained. The initial estimates may then be provided to an optimization model of the valve annulus to obtain a highly accurate prediction of the cross-section of the valve annulus.Type: GrantFiled: November 20, 2017Date of Patent: March 10, 2020Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Ram Kumar Balachandran, Ramji T. Venkatasubramanian, Anthony David Hill, John Hauck, Neelakantan Saikrishnan, Riki Thao
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Publication number: 20200038177Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.Type: ApplicationFiled: October 1, 2019Publication date: February 6, 2020Inventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Cyril J. Schweich, Todd J. Mortier
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Patent number: 10449039Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.Type: GrantFiled: March 17, 2016Date of Patent: October 22, 2019Assignee: Caisson Interventional, LLCInventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Cyril J. Schweich, Jr., Todd J. Mortier
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Publication number: 20190038409Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The stent is formed of a plurality of struts. A cuff is coupled to the stent. The cuff has one or more features configured to reduce abrasion and/or perivalvular leakage.Type: ApplicationFiled: October 10, 2018Publication date: February 7, 2019Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Julia A. Schraut, Peter N. Braido, Ramji T. Venkatasubramanian, Aditee Kurane, Mina S. Fahim, Jaishankar Kutty
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Patent number: 10136992Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. The heart valve further includes a collapsible and expandable valve assembly including a cuff and a plurality of leaflets, the cuff being coupled to selected ones of the plurality of struts and having microspheres disposed therein. The microspheres are capable of expanding upon contact with blood.Type: GrantFiled: June 22, 2015Date of Patent: November 27, 2018Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Julia A. Schraut, Peter N. Braido, Ramji T. Venkatasubramanian, Aditee Kurane, Mina S. Fahim, Jaishankar Kutty
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Publication number: 20180221147Abstract: Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Some embodiments of prosthetic valves described herein include an anchor portion that couples to the anatomy near a native valve, and a valve portion that is mateable with the anchor portion. In some such embodiments, the anchor portion and/or the deployment system includes one or more prosthetic elements that temporarily augment or replace the sealing function of the native valve leaflets.Type: ApplicationFiled: February 6, 2018Publication date: August 9, 2018Inventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Todd J. Mortier, Cyril J. Schweich, Jr., Benjamin L. Montag, Steven N. Willard
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Patent number: 9974647Abstract: Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy.Type: GrantFiled: March 31, 2015Date of Patent: May 22, 2018Assignee: Caisson Interventional, LLCInventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Andrew T. Forsberg, Alex A. Peterson, Cyril J. Schweich, Jr., Todd J. Mortier
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Publication number: 20180078177Abstract: A system for detecting the dimensions and geometry of a native valve annulus for trans-catheter valve implantation includes a compliant balloon and a shaft within the balloon. One or more drive electrodes may be affixed to a surface of the balloon, and one or more sense electrodes may be affixed to the shaft. After insertion of the balloon into the native valve annulus, the drive electrodes may be energized with a predetermined voltage. Using a trained statistical model and the voltages measured at the sense electrodes, initial estimates of the cross-section of the valve annulus may be obtained. The initial estimates may then be provided to an optimization model of the valve annulus to obtain a highly accurate prediction of the cross-section of the valve annulus.Type: ApplicationFiled: November 20, 2017Publication date: March 22, 2018Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Ram Kumar Balachandran, Ramji T. Venkatasubramanian, Anthony David Hill, John Hauck, Neelakantan Saikrishnan, Riki Thao
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Publication number: 20180049877Abstract: A sizing device for a collapsible prosthetic heart valve includes a collapsible and expandable stent. The stent has an annulus section at a first end with a first diameter and an aortic section at a second end with a second diameter. The second diameter is greater than the first diameter, and the first end and the second end are disposed at opposite sides of the stent. A sensor is coupled adjacent the first diameter of the stent and is capable of collecting information related to stiffness of a native valve annulus by contacting portions of the native valve annulus. A method for determining the fitment of a prosthetic heart valve within a native valve annulus is also provided.Type: ApplicationFiled: October 27, 2017Publication date: February 22, 2018Applicant: St. Jude Medical, Cardiology Division, Inc.Inventor: Ramji T. Venkatasubramanian
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Patent number: 9867556Abstract: A system for detecting the dimensions and geometry of a native valve annulus for trans-catheter valve implantation includes a compliant balloon and a shaft within the balloon. One or more drive electrodes may be affixed to a surface of the balloon, and one or more sense electrodes may be affixed to the shaft. After insertion of the balloon into the native valve annulus, the drive electrodes may be energized with a predetermined voltage. Using a trained statistical model and the voltages measured at the sense electrodes, initial estimates of the cross-section of the valve annulus may be obtained. The initial estimates may then be provided to an optimization model of the valve annulus to obtain a highly accurate prediction of the cross-section of the valve annulus.Type: GrantFiled: February 6, 2015Date of Patent: January 16, 2018Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Ram Kumar Balachandran, Ramji T. Venkatasubramanian, Anthony David Hill, John Hauck, Neelakantan Saikrishnan, Riki Thao
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Publication number: 20180000586Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae.Type: ApplicationFiled: August 24, 2017Publication date: January 4, 2018Inventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Andrew T. Forsberg, Cyril J. Schweich, JR., Todd J. Mortier, Erik O. Martz, Douglas J. Krone
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Patent number: 9808342Abstract: A sizing device for a collapsible prosthetic heart valve, the sizing device includes a collapsible and expandable balloon having a proximal end, a distal end. At least one microelectromechanical sensor is coupled to the balloon, the at least one sensor being capable of measuring information related to size and stiffness of tissue.Type: GrantFiled: March 7, 2013Date of Patent: November 7, 2017Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Ramji T. Venkatasubramanian, Peng Peng
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Patent number: 9801721Abstract: A sizing device for a collapsible prosthetic heart valve includes a collapsible and expandable stent. A microelectromechanical sensor is coupled to the stent, the sensor being capable of collecting information related to the size and stiffness of tissue.Type: GrantFiled: March 7, 2013Date of Patent: October 31, 2017Assignee: St. Jude Medical, Cardiology Division, Inc.Inventor: Ramji T. Venkatasubramanian
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Patent number: 9750607Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae.Type: GrantFiled: March 31, 2015Date of Patent: September 5, 2017Assignee: Caisson Interventional, LLCInventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Andrew T. Forsberg, Cyril J. Schweich, Jr., Todd J. Mortier, Erik O. Martz, Douglas J. Krone
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Publication number: 20170189177Abstract: Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Some embodiments of prosthetic mitral valves described herein include an anchor portion that couples the prosthetic mitral valve to the anatomy near the native mitral valve, and a valve portion that is mateable with the anchor portion.Type: ApplicationFiled: December 29, 2016Publication date: July 6, 2017Inventors: Cyril J. Schweich, JR., Kavitha Ganesan, Ramji T. Venkatasubramanian, Erik O. Martz, Lucas T. Schneider, Todd J. Mortier
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Publication number: 20160270911Abstract: Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.Type: ApplicationFiled: March 17, 2016Publication date: September 22, 2016Inventors: Kavitha Ganesan, Ramji T. Venkatasubramanian, Cyril J. Schweich, JR., Todd J. Mortier