Abstract: A combined disposable toothbrush and detachable toothpaste cartridge includes a hollow cylindrical handle portion having opposed proximal and distal bases and a cylindrical sidewall disposed therebetween, the proximal each base having an axial recess, an exterior surface of the proximal base proportioned for engagement between a thumb and a finger of a user, the distal base including an outlet passage, a threaded rod having a proximal end rigidly secured within the recess of the proximal base; a cylindrical push block having a circumferential surface in fluid-tight frictional communication with an inner surface of the cylindrical sidewall and having an axial channel in thread-fit co-action with the threaded rod; and a detachable brush portion having, at a distal end thereof, a head including brushing bristles and an internal channel extending longitudinally and having an outlet in communication with the brushing bristles; and a coupling for selectably attaching and detaching a distal end of the handle portion