Patents by Inventor Ran Kornowski
Ran Kornowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230282365Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives, from a medical imaging device, a medical image of a coronary vessel tree of a subject and calculates a plurality of geometric measurements associated with individual portions of a vascular segment of the coronary vessel tree. The apparatus also determines a plurality of resistances associated with the plurality of geometric measurements associated with the individual portions of the vascular segment and determines a plurality of pressure drops across the individual portions of the vascular segment based on the determined resistances and a calculated or estimated blood flow. The apparatus further calculates based on the plurality of pressure drops, a functional index indicative of a presence or an absence of a stenosis within the vascular segment.Type: ApplicationFiled: March 10, 2023Publication date: September 7, 2023Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 11728037Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processes the images to produce a stenotic model over the vasculature. The stenotic model has measurements of the vasculature at one or more locations along vessels of the vasculature. The apparatus, in some embodiments, determines a flow characteristic of the stenotic model and calculates an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.Type: GrantFiled: August 2, 2021Date of Patent: August 15, 2023Assignee: CathWorks Ltd.Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 11615894Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives, from a medical imaging device, a medical image of a coronary vessel tree of a subject and calculates a plurality of geometric measurements associated with individual portions of a vascular segment of the coronary vessel tree. The apparatus also determines a plurality of resistances associated with the plurality of geometric measurements associated with the individual portions of the vascular segment and determines a plurality of pressure drops across the individual portions of the vascular segment based on the determined resistances and a calculated or estimated blood flow. The apparatus further calculates based on the plurality of pressure drops, a functional index indicative of a presence or an absence of a stenosis within the vascular segment.Type: GrantFiled: May 23, 2022Date of Patent: March 28, 2023Assignee: Cathworks, Ltd.Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Publication number: 20230084748Abstract: A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.Type: ApplicationFiled: August 5, 2022Publication date: March 16, 2023Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Publication number: 20220310265Abstract: An apparatus for performing a vascular assessment is disclosed. The apparatus creates a three-dimensional model that is representative of a coronary vessel tree of a patient based on at least two angiographic images. The apparatus estimates first blood flow resistance values for points along at least some vascular segments of the coronary vessel tree using vascular geometrical dimensions of the three-dimensional model. The apparatus also estimates second blood flow resistance values for the points along the at least some vascular segments of the coronary vessel tree using a volume of a crown of the vascular segment downstream from the respective point. The apparatus determines fractional flow reserve (“FFR”) by calculating a ratio of the first blood flow resistance values and the second blood flow resistance values at each of the points along the at least some vascular segments of the coronary vessel tree.Type: ApplicationFiled: April 4, 2022Publication date: September 29, 2022Inventors: Nessi Benishti, Ifat Lavi, Ran Kornowski, Idit Avrahami, Guy Lavi
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Publication number: 20220285034Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives, from a medical imaging device, a medical image of a coronary vessel tree of a subject and calculates a plurality of geometric measurements associated with individual portions of a vascular segment of the coronary vessel tree. The apparatus also determines a plurality of resistances associated with the plurality of geometric measurements associated with the individual portions of the vascular segment and determines a plurality of pressure drops across the individual portions of the vascular segment based on the determined resistances and a calculated or estimated blood flow. The apparatus further calculates based on the plurality of pressure drops, a functional index indicative of a presence or an absence of a stenosis within the vascular segment.Type: ApplicationFiled: May 23, 2022Publication date: September 8, 2022Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 11406337Abstract: A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.Type: GrantFiled: March 23, 2020Date of Patent: August 9, 2022Assignee: Cathworks Ltd.Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 11295864Abstract: An apparatus for vascular modeling is disclosed. The apparatus receives medical images from an imaging device that include representations of a coronary vessel tree of a subject recorded at a different viewing angles. The apparatus determines, from a first of the medical images, a first centerline set and first vessel diameters for sample points along the first centerline set, and determines, from a second of the medical images, a second centerline set and second vessel diameters for sample points along the second centerline set. The apparatus determines a correspondence between the first centerline set and the second centerline set, and determines diameters for a combined centerline set based on the correspondence of sample points along the first and second centerline sets. The apparatus provides the combined centerline set for estimating blood flow resistance values of the coronary vessel tree of the subject to determine at least one potential stenosis.Type: GrantFiled: November 11, 2019Date of Patent: April 5, 2022Assignee: Cath Works Ltd.Inventors: Nessi Benishti, Ifat Lavi, Ran Kornowski, Idit Avrahami, Guy Lavi
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Publication number: 20210375474Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processes the images to produce a stenotic model over the vasculature. The stenotic model has measurements of the vasculature at one or more locations along vessels of the vasculature. The apparatus, in some embodiments, determines a flow characteristic of the stenotic model and calculates an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.Type: ApplicationFiled: August 2, 2021Publication date: December 2, 2021Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 11081237Abstract: A method for real-time vascular modeling and assessment is disclosed. Modeling, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels and construct 3-D vascular extents and determine other vascular characteristics. Assessment, in some embodiments, comprises processing models selectively different from one another to produce one or more vascular indexes which indicate a diagnostic preference, for example, to perform a medical intervention such as a stent implantation. Speed is achieved, for example, by the method being optimized for determining the effects of a medical intervention. In some embodiments, results are produced quickly enough to allow use of the method to perform PCI within the same catheterization used to perform diagnostic imaging.Type: GrantFiled: February 7, 2020Date of Patent: August 3, 2021Assignee: CathWorks Ltd.Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 10835709Abstract: Attachment of tubes of various constructions for use in a microcatheter, including joining to a multifilar helix. Methods of uses and construction with concentric tubes axially displaceable over one another to control navigability and/or positioning properties of a microcatheter.Type: GrantFiled: November 4, 2014Date of Patent: November 17, 2020Assignee: Nitiloop Ltd.Inventors: Ran Kornowski, Dvir Keren
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Patent number: 10803994Abstract: A vascular assessment apparatus is disclosed. The apparatus is configured to receive medical images of a coronary vessel tree of a subject from a medical imaging device and analyze the medical images to identify vessel segments within the coronary vessel tree. For each identified vessel segment, the apparatus is configured to determine flow rates at each identified vessel segment and calculate an index indicative of vascular function based on the determined flow rates.Type: GrantFiled: August 26, 2019Date of Patent: October 13, 2020Assignee: CathWorks LtdInventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 10773052Abstract: An aspect of some embodiments of the application relates to a microcatheter comprising a deployment element disposed about around at least a portion of an exterior of a distal end of the microcatheter, the deployment element configured for repeatedly expanding and collapsing, the distal end arranged to allow forward or reverse axial displacement while the deployment element maintains a position, the deployment element arranged for positioning the microcatheter distal end approximately in the middle of a vessel.Type: GrantFiled: August 6, 2018Date of Patent: September 15, 2020Assignee: Nitiloop Ltd.Inventors: Ran Kornowski, Dvir Keren
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Publication number: 20200281553Abstract: A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.Type: ApplicationFiled: March 23, 2020Publication date: September 10, 2020Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Publication number: 20200251223Abstract: A method for real-time vascular modeling and assessment is disclosed. Modeling, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels and construct 3-D vascular extents and determine other vascular characteristics. Assessment, in some embodiments, comprises processing models selectively different from one another to produce one or more vascular indexes which indicate a diagnostic preference, for example, to perform a medical intervention such as a stent implantation. Speed is achieved, for example, by the method being optimized for determining the effects of a medical intervention. In some embodiments, results are produced quickly enough to allow use of the method to perform PCI within the same catheterization used to perform diagnostic imaging.Type: ApplicationFiled: February 7, 2020Publication date: August 6, 2020Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 10595807Abstract: A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.Type: GrantFiled: January 15, 2014Date of Patent: March 24, 2020Assignee: CathWorks LtdInventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Publication number: 20200077968Abstract: An apparatus for vascular modeling is disclosed. The apparatus receives medical images from an imaging device that include representations of a coronary vessel tree of a subject recorded at a different viewing angles. The apparatus determines, from a first of the medical images, a first centerline set and first vessel diameters for sample points along the first centerline set, and determines, from a second of the medical images, a second centerline set and second vessel diameters for sample points along the second centerline set. The apparatus determines a correspondence between the first centerline set and the second centerline set, and determines diameters for a combined centerline set based on the correspondence of sample points along the first and second centerline sets. The apparatus provides the combined centerline set for estimating blood flow resistance values of the coronary vessel tree of the subject to determine at least one potential stenosis.Type: ApplicationFiled: November 11, 2019Publication date: March 12, 2020Inventors: Nessi Benishti, Ifat Lavi, Ran Kornowski, Idit Avrahami, Guy Lavi
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Patent number: 10559388Abstract: A method for real-time vascular modeling and assessment is disclosed. Modeling, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels and construct 3-D vascular extents and determine other vascular characteristics. Assessment, in some embodiments, comprises processing models selectively different from one another to produce one or more vascular indexes which indicate a diagnostic preference, for example, to perform a medical intervention such as a stent implantation. Speed is achieved, for example, by the method being optimized for determining the effects of a medical intervention. In some embodiments, results are produced quickly enough to allow use of the method to perform PCI within the same catheterization used to perform diagnostic imaging.Type: GrantFiled: February 18, 2019Date of Patent: February 11, 2020Assignee: CathWorks Ltd.Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Publication number: 20190385745Abstract: A vascular assessment apparatus is disclosed. The apparatus is configured to receive medical images of a coronary vessel tree of a subject from a medical imaging device and analyze the medical images to identify vessel segments within the coronary vessel tree. For each identified vessel segment, the apparatus is configured to determine flow rates at each identified vessel segment and calculate an index indicative of vascular function based on the determined flow rates.Type: ApplicationFiled: August 26, 2019Publication date: December 19, 2019Inventors: Ifat Lavi, Ran Kornowski, Idit Avrahami, Nessi Benishti, Guy Lavi
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Patent number: 10470730Abstract: A method for vascular modeling is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to automatically detect 2-D features, for example, paths along vascular extents, which are projected into 3-D to determine homologous features among blood vessels. In some embodiments, projection and/or image registration is iteratively altered to improve feature position matching. Based on 3-D vascular extents and their registration to 2-D images, additional features such as vascular width are optionally determined and added to the model.Type: GrantFiled: November 10, 2017Date of Patent: November 12, 2019Assignee: CathWorks Ltd.Inventors: Nessi Benishti, Ifat Lavi, Ran Kornowski, Idit Avrahami, Guy Lavi