Abstract: An example system includes a first lead configured to be positioned in or beside a left internal jugular vein (IJV) of a patient to deliver a first stimulation signal to a first vagus nerve, the first lead including one or more first segmented electrodes positioned on a distal portion of the first lead and a first anchoring mechanism; a second lead configured to be positioned in or beside a right IJV of the patient to deliver a second stimulation signal to a second vagus nerve, the second lead including one or more second segmented electrodes positioned on a distal portion of the second lead and a second anchoring mechanism; and circuitry configured to deliver electrical energy to the first lead to deliver the first stimulation signal and the second lead to deliver the second stimulation signal to provide bilateral stimulation to the first vagus nerve and the second vagus nerve.

Abstract: A sensor including electrodes, a control module and a physical layer module. The electrodes are configured to (i) attach to a patient, and (ii) receive a first electromyographic signal from the patient. The control module is connected to the electrodes. The control module is configured to (i) detect the first electromyographic signal, and (ii) generate a first voltage signal. The physical layer module is configured to: receive a payload request from a console interface module or a nerve integrity monitoring device; and based on the payload request, (i) upconvert the first voltage signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the sensor to the console interface module or the nerve integrity monitoring device.

Abstract: A method of implanting a lead includes inserting a needle through tissue near a chin of a patient and through a tongue of the patient, inserting an introducer through an opening created by the needle, and inserting the lead through the introducer, the lead comprising an elongated member and one or more electrodes in a distal portion of the elongated member such that the one or more electrodes are implantable proximate to one or more motor points of a protrusor muscle within the tongue of the patient, wherein inserting the lead comprises inserting the lead to have a shape of one of a helix, a compound helix, a wave shape, or saw-tooth shape, or to have a loop in the lead.

Abstract: An example method includes receiving one or more physiological signals; detecting an apnea event based on the one or more physiological signals; determining that the apnea event cannot be characterized as one of a normal, OSA (obstructive sleep apnea), CSA (central sleep apnea), or combination OSA/CSA event; and outputting an electrical stimulation as a default based on determining that the apnea event cannot be characterized as a normal event, an OSA event, a CSA event, or combination OSA/CSA events.

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

Abstract: A system includes a sheet flexible material having a contact surface adapted to be placed on an outer surface of a patient's body. A plurality of sensing apparatuses have respective sensing surfaces distributed across the contact surface of the sheet. One or more of the sensing apparatuses include a multimodal sensing apparatus. Each multimodal sensing apparatus includes a monolithic substrate carrying a transducer, circuitry and an electrophysiological sensor. The transducer is coupled to the circuitry and configured to at least sense acoustic energy from a transducer location of the sheet. The electrophysiological sensor is also coupled to the circuitry, and the sensor is configured to at least sense electrophysiological signals from a sensor location of the sheet, in which the sensor location has a known spatial position relative to the transducer location.

Abstract: A sensor including electrodes, a control module and a physical layer module. The electrodes are configured to (i) attach to a patient, and (ii) receive a first electromyographic signal from the patient. The control module is connected to the electrodes. The control module is configured to (i) detect the first electromyographic signal, and (ii) generate a first voltage signal. The physical layer module is configured to: receive a payload request from a console interface module or a nerve integrity monitoring device; and based on the payload request, (i) upconvert the first voltage signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the sensor to the console interface module or the nerve integrity monitoring device.

Abstract: Novel tools and techniques are provided for presenting patient information to a user. In some embodiments, a computer system may: receive device data associated with one or more devices configured to perform a cardiac shunting procedure to change a cardiac blood flow pattern to improve cardiac blood flow efficiency or cardiac pumping efficiency; receive one or more imaging data associated with one or more imaging devices configured to generate images of one or more internal portions of the patient; analyze the device data and the imaging data; map the device data and the imaging data to a multi-dimensional representation of the one or more internal portions of the patient; generate one or more image-based outputs based at least in part on the mapping; and present, using a user experience (“UX”) device, the generated one or more image-based outputs.

Abstract: A system for sensing physiological traits of a maternal patient and a fetal patient carried by the maternal patient during a pregnancy using one or more sensors. The system may use the physiological traits sensed to define a maternal attribute for the maternal patient and a fetal attribute for the fetal patient, such as a heart rate, blood pressure, respiration rate, temperature, oxygen saturation level, or other attributes. The system is configured to compare the maternal attribute to a maternal limit describing a threshold for the maternal patient and/or compare the fetal attribute to a fetal limit describing a threshold for the fetal patient. The system is configured to issue a communication to the maternal patient and/or a clinician based on the comparisons. In examples, the system regularly communicates the maternal attribute and/or the fetal attribute to an output device of the maternal patient and/or a clinician.

Abstract: A system for sensing one or more physiological traits and obstetric conditions, such as a fertility phase, pregnancy, labor, post-partum conditions, and other conditions related to the reproductive system of the patient. The system may use the one or more physiological traits sensed to define one or more patient attributes for the patient, such as a hormone level, heart rate, blood pressure, respiration rate, temperature, oxygen saturation level, uterine contractions, fluid level, and/or other patient attributes. The system is configured to compare the one or more patient attributes to one or more attribute signs describing a threshold for the one or more patient attributes. The system is configured to issue a communication to the patient and/or a clinician based on the comparisons. The system may be configured to assess and indicate reproductive phases for the patient over a life-cycle from the fertility phase to the post-partum phase.

Abstract: A biocompatible medical device may include an electrochemical sensor including a common reference electrode; at least one counter electrode; and a work electrode platform comprising a plurality of respective work electrodes, each respective work electrode electrically coupled to the common reference electrode and comprising a respective reagent substrate configured to react with a respective analyte to produce a respective signal indicative of a concentration of the respective analyte; and processing circuitry operatively coupled to the electrochemical sensor, and configured to receive from the electrochemical sensor a plurality of signals from the plurality of respective work electrodes; identify the respective signal corresponding to a respective selected work electrode; and process the identified signal to determine the concentration of the respective analyte associated with the respective selected work electrode.

Abstract: An implantable medical device (IMD) includes therapy delivery circuitry, sensing circuitry, and processing circuitry. The processing circuitry is configured to determine one or more sleep apnea therapy parameters, control the therapy delivery circuitry to deliver sleep apnea therapy via a first set of electrodes implantable within the patient in accordance with the one or more sleep apnea therapy parameters, and at least one of: (1) monitor a cardiac signal sensed with the sensing circuitry, or (2) determine one or more cardiac therapy parameters, and control the therapy delivery circuitry to deliver cardiac therapy via a second set of electrodes implantable within the patient in accordance with the one or more cardiac therapy parameters.

Abstract: A nerve integrity monitoring device includes a control module and a physical layer module. The control module is configured to generate a payload request. The payload request (i) requests a data payload from a sensor in a wireless nerve integrity monitoring network, and (ii) indicates whether a stimulation probe device is to generate a stimulation pulse. The physical layer module is configured to (i) wirelessly transmit the payload request to the sensor and the stimulation probe device, or (ii) transmit the payload request to a console interface module. The physical layer module is also configured to, in response to the payload request, (i) receive the data payload from the sensor, and (ii) receive stimulation pulse information from the stimulation probe device. The data payload includes data corresponding to an evoked response of a patient. The evoked response is generated based on the stimulation pulse.

Abstract: An example method includes receiving one or more physiological signals; detecting an apnea event based on the one or more physiological signals; determining that the apnea event cannot be characterized as one of a normal, OSA (obstructive sleep apnea), CSA (central sleep apnea), or combination OSA/CSA event; and outputting an electrical stimulation as a default based on determining that the apnea event cannot be characterized as a normal event, an OSA event, a CSA event, or combination OSA/CSA events.

Abstract: A sensor including electrodes, a control module and a physical layer module. The electrodes are configured to (i) attach to a patient, and (ii) receive a first electromyographic signal from the patient. The control module is connected to the electrodes. The control module is configured to (i) detect the first electromyographic signal, and (ii) generate a first voltage signal. The physical layer module is configured to: receive a payload request from a console interface module or a nerve integrity monitoring device; and based on the payload request, (i) upconvert the first voltage signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the sensor to the console interface module or the nerve integrity monitoring device.

Abstract: In some examples, an apparatus configured to be worn by a patient for cardiac defibrillation comprises sensing electrodes configured to sense a cardiac signal of the patient, defibrillation electrodes, therapy delivery circuitry configured to deliver defibrillation therapy to the patient via the defibrillation electrodes, communication circuitry configured to receive data of at least one physiological signal of the patient from at least one sensing device separate from the apparatus, a memory configured to store the data, the cardiac signal, and a machine learning algorithm, and processing circuitry configured to apply the machine learning algorithm to the data and the cardiac signal to probabilistically-determine at least one state of the patient and determine whether to control delivery of the defibrillation therapy based on the at least one probabilistically-determined patient state.

Abstract: A stimulation probe device including a first electrode, a stimulation module, a control module and a physical layer module. The stimulation module is configured to (i) wirelessly receive a payload signal from a console interface module or a nerve integrity monitoring device, and (ii) supply a voltage or an amount of current to the first electrode to stimulate a nerve or a muscle in a patient. The control module is configured to generate a parameter signal indicating the voltage or the amount of current supplied to the electrode. The physical layer module is configured to (i) upconvert the parameter signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the stimulation probe to the console interface module or the nerve integrity monitoring device.

Abstract: A sleep apnea and obesity comorbidity treatment system includes a transceiver and a control module. The control module is configured to: receive sensor data, where the sensor data is indicative of a glucose level of a patient and a ketones level of the patient, transmit the sensor data to a remote feedback device, receive feedback information from the remote feedback device based on the sensor data, and where the feedback information provides indications to the patient to maintain or alter a behavior of the patient based on the glucose level and the ketones level, and based on the feedback information, performing an operation to maintain or alter at least one of a diet or physical activity of the patient.

Abstract: A method of treating or preventing acute respiratory distress syndromes (ARDS) includes advancing a cryogenic treatment element into a target bronchus of a mammal and exchanging cryogenic energy between the target bronchus and the cryogenic treatment element for a predetermined period of time until a target temperature of the target bronchus is reached to cause neuropraxia of nerves within the target bronchus.

Abstract: Disclosed is a system for stimulation of a subject. The stimulation may be to provide therapy to treat the subject. Stimulation may be of selected muscle groups and/or portions.