Abstract: A patient restraint garment, which is quickly applied to or removed from a patient and which is substantially non-defeatable by the patient, is disclosed which comprises: a flexible panel having an opening to receive the head and neck of a patient thereby forming front and rear portions covering the upper torso of the patient; tying straps attached to the bottom corners of the front portion of the panel for engagement with at least one of a plurality of loops attached to the bottom region of the rear portion of the panel, to connect and snug the bottom regions of the front and rear portions of the panel about the patient, prior to securing the tying straps to a structure out of reach of the patient, at least one side strap extending laterally from each side of the front portion of the panel, at chest level, which straps have fastening means thereon for engagement with a portion of a receiving means attached to the upper back region of the rear portion of the panel to create custom-fit, adjustable arm holes fo