Abstract: Compounds provided herein function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their preparation.

Abstract: A lid of molded plastic construction, includes a lid body and a cap attached to the lid body by a tether. The tether is substantially continuous with an adjacent peripheral edge of the lid body, with a tear zone between the tether and the adjacent peripheral edge of the lid body formed during molding of the lid. The tear zone is disruptable by application of a tearing pressure to free the tether from the peripheral edge.

Abstract: A mold for forming a lid having a cap connected to the lid by a tether. The mold has mold features for forming a lid body having a peripheral edge, a cap, a tether connecting the cap to the lid body, and a tear zone. The mold feature for forming the tear zone includes an elongate ridge located between the mold feature for the tether and the mold feature for the lid body for providing a reduced thickness flow path proximate the ridge that connects between the mold feature for forming the lid body and the tether.

Abstract: A system for converting an analog signal to a digital signal may include a plurality of converter stages. One of the converter stages may include a multiplying digital-to-analog converter (MDAC) and an analog-to-digital subconverter (ADSC). The MDAC may be configured to (i) receive from a previous stage a first residue analog signal and a first idealized digital signal representing a first portion of the digital signal and corresponding to the first residue analog signal; (ii) convert the first idealized digital signal to an idealized analog signal; and (iii) output a second residue analog signal based on the difference between the first residue analog signal and the idealized analog signal. The ADSC may be configured to convert the second residue analog signal into a second idealized digital signal representing a second portion of the digital signal and corresponding to the second residue analog signal, the ADSC comprising a sloping analog-to-digital converter.

Abstract: A system for converting an analog signal to a digital signal may include a plurality of converter stages. One of the converter stages may include a multiplying digital-to-analog converter (MDAC) and an analog-to-digital subconverter (ADSC). The MDAC may be configured to (i) receive from a previous stage a first residue analog signal and a first idealized digital signal representing a first portion of the digital signal and corresponding to the first residue analog signal; (ii) convert the first idealized digital signal to an idealized analog signal; and (iii) output a second residue analog signal based on the difference between the first residue analog signal and the idealized analog signal. The ADSC may be configured to convert the second residue analog signal into a second idealized digital signal representing a second portion of the digital signal and corresponding to the second residue analog signal, the ADSC comprising a sloping analog-to-digital converter.

Abstract: A modular house is constructed with Engineered Structural Modular Units (EMSU's) made from Stucturally Engineered Oriented Strand Boards (SEOSB's). Unitized structures are formed from modular units comprising two SEOSB panels with internal webbing for floor, wall, ceiling and roof modules; and adapter units such as corner adapter units, U-channel adapters, alignment connectors, trim adapters, and roof support adapters. Window and door openings can be cut on-site during construction. Any insulation meeting local building code requirements can be installed on-site. Standard electrical, plumbing, and mechanical products and procedures can be used as required by local building codes. All roofing and exterior wall coverings that meet local building codes can be used as required by architectural design.

Abstract: A cold can or bottle cooler dispenser for keeping cold and compactly transporting both homemade liquid refreshment and canned or bottled refreshments in separate compartments. A rotatable cowling having an opening which surrounds the mid-section of the cooler allows selection of the desired canned or bottled refreshment. Thus after the homemade liquid refreshment has been placed in the cooler, it need never thereafter be exposed either when loading the canned or bottled refreshments or when accessing either the canned or the homemade refreshments. Compartments are also provided for reusable substitute ice packs. A spigot on the outside of the cooler allows one to access the homemade liquid refreshment. Another embodiment of this invention can be used to retrofit or modify an existing cooler so that the modified cooler can now be used to carry both a home-made beverage and canned beverages with both beverages being kept conveniently segregated from one another.