Patents by Inventor Randel Dorian
Randel Dorian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10737012Abstract: Disclosed is a device for separating a cellular component from a multicomponent fluid. The device can include a body, a first acoustic wave generator, and a second acoustic wave propagating component. The body can define a channel having a first surface, an opposing second surface, a first side, and an opposing second side. The channel can extend along a longitudinal axis from a first end to an opposing second end. The first acoustic wave generator can be coupled to the first surface. The second acoustic wave propagating component can be coupled to the second surface. The first acoustic wave generator and second acoustic wave propagating component can be configured to generate a bulk standing acoustic wave in the channel.Type: GrantFiled: July 22, 2016Date of Patent: August 11, 2020Assignee: Biomet Biologics, Inc.Inventors: Michael D. Leach, Ned M. Hamman, David Abeskaron, Grant Cunningham, Randel Dorian, Richard Wood Storrs, Scott R. King
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Patent number: 9855382Abstract: Devices for washing a composition including cells are provided. The devices include a separation channel, a first wave component and a second wave component. The separation channel is positioned between the first and second wave components. Collectively, the wave components generate a standing bulk acoustic wave that isolates cells from the composition.Type: GrantFiled: March 31, 2015Date of Patent: January 2, 2018Assignee: Biomet Biologics, LLCInventors: Michael D. Leach, Ned M. Hamman, David Abeskaron, Grant D. Cunningham, Randel Dorian, Richard W. Storrs, Scott R. King
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Patent number: 9757721Abstract: A method for washing a suspension of cells including a suspension fluid and a plurality of cells is provided. The method includes using centripetal force to generate a layer of wash solution against a cylindrical wall and to generate a cell suspension layer adjacent to the layer of wash solution. The method also includes forcing the cells through the layer of wash solution to generate a layer of clean cells. Devices for performing the method are also provided.Type: GrantFiled: May 11, 2015Date of Patent: September 12, 2017Assignee: Biomet Biologics, LLCInventors: Michael D. Leach, Randel Dorian, Richard W. Storrs, Scott R. King
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Patent number: 9719063Abstract: Disclosed is a system to separate, enrich, and/or purify a cellular population from a biological tissue, such as a tissue sample. For example, an adipose tissue sample can be acquired and disrupted. The disrupted tissue sample can then be separated and purified. The separated components can include multipotent, pluripotent, or other cell populations.Type: GrantFiled: August 11, 2014Date of Patent: August 1, 2017Assignee: Biomet Biologics, LLCInventors: Randel Dorian, Michael D. Leach, Richard W. Storrs, Jason Chavarria
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Patent number: 9696242Abstract: A separation device that can include a separation tube or container that has a wall defining an internal volume into which a material can be placed is disclosed. The material can include a multi-component mixture or solution. A secondary tube or withdrawal cannula can be placed and/or moved within the tube to withdrawal a material form the tube.Type: GrantFiled: October 9, 2014Date of Patent: July 4, 2017Assignee: Biomet Biologics, LLCInventors: Trenton Walker, Matthew D. Landrigan, Michael D. Leach, Scott R. King, Randel Dorian, Richard W. Storrs
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Patent number: 9649579Abstract: A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.Type: GrantFiled: December 10, 2012Date of Patent: May 16, 2017Assignees: Hanuman LLC, Biomet Biologics, LLCInventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
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Publication number: 20160332158Abstract: A method for washing a suspension of cells including a suspension fluid and a plurality of cells is provided. The method includes using centripetal force to generate a layer of wash solution against a cylindrical wall and to generate a cell suspension layer adjacent to the layer of wash solution. The method also includes forcing the cells through the layer of wash solution to generate a layer of clean cells. Devices for performing the method are also provided.Type: ApplicationFiled: May 11, 2015Publication date: November 17, 2016Inventors: Michael D. LEACH, Randel DORIAN, Richard W. STORRS, Scott R. KING
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Publication number: 20160325039Abstract: Disclosed is a device for separating a cellular component from a multicomponent fluid. The device can include a body, a first acoustic wave generator, and a second acoustic wave propagating component. The body can define a channel having a first surface, an opposing second surface, a first side, and an opposing second side. The channel can extend along a longitudinal axis from a first end to an opposing second end. The first acoustic wave generator can be coupled to the first surface. The second acoustic wave propagating component can be coupled to the second surface. The first acoustic wave generator and second acoustic wave propagating component can be configured to generate a bulk standing acoustic wave in the channel.Type: ApplicationFiled: July 22, 2016Publication date: November 10, 2016Inventors: Michael D. Leach, Ned M. Hamman, David Abeskaron, Grant Cunningham, Randel Dorian, Richard Wood Storrs, Scott R. King
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Publication number: 20160287778Abstract: Devices for washing a composition including cells are provided. The devices include a separation channel, a first wave component and a second wave component. The separation channel is positioned between the first and second wave components. Collectively, the wave components generate a standing bulk acoustic wave that isolates cells from the composition.Type: ApplicationFiled: March 31, 2015Publication date: October 6, 2016Inventors: Michael D. LEACH, Ned M. HAMMAN, David ABESKARON, Grant D. CUNNINGHAM, Randel DORIAN, Richard W. STORRS, Scott R. KING
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Patent number: 9138664Abstract: A separator system operable to use centrifugation to fractionate a multiple component material, such as a suspension including blood, comprises a buoy. The buoy can be carried in a separation container and has a tuned density that is configured to reach an equilibrium position in the multiple component material. A guide surface is carried on a buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.Type: GrantFiled: December 2, 2013Date of Patent: September 22, 2015Assignees: Biomet Biologics, LLC, Hanuman, LLCInventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
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Publication number: 20150104824Abstract: A separation device that can include a separation tube or container that has a wall defining an internal volume into which a material can be placed is disclosed. The material can include a multi-component mixture or solution. A secondary tube or withdrawal cannula can be placed and/or moved within the tube to withdrawal a material form the tube.Type: ApplicationFiled: October 9, 2014Publication date: April 16, 2015Inventors: Trenton WALKER, Matthew D. Landrigan, Michael D. Leach, Scott R. King, Randel Dorian, Richard W. Storrs
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Patent number: 8950586Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.Type: GrantFiled: July 1, 2013Date of Patent: February 10, 2015Assignee: Hanuman LLCInventors: Randel Dorian, Richard W. Storrs, Scott R. King
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Publication number: 20140349388Abstract: Disclosed is a system to separate, enrich, and/or purify a cellular population from a biological tissue, such as a tissue sample. For example, an adipose tissue sample can be acquired and disrupted. The disrupted tissue sample can then be separated and purified. The separated components can include multipotent, pluripotent, or other cell populations.Type: ApplicationFiled: August 11, 2014Publication date: November 27, 2014Inventors: Randel DORIAN, Michael D. Leach, Richard W. Storrs, Jason Chavarria
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Patent number: 8801586Abstract: Disclosed is a system to separate, enrich, and/or purify a cellular population from a biological tissue, such as a tissue sample. For example, an adipose tissue sample can be acquired and disrupted. The disrupted tissue sample can then be separated and purified. The separated components can include multipotent, pluripotent, or other cell populations.Type: GrantFiled: December 20, 2012Date of Patent: August 12, 2014Assignee: Biomet Biologics, LLCInventors: Randel Dorian, Michael D. Leach, Richard W. Storrs, Jason Chavarria
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Publication number: 20140154234Abstract: Methods of generating thrombin and methods of applying a clotting tissue sealant to a site on a subject are provided. A blood component comprising platelets can be obtained from the subject. A hypotonic composition is contacted with a solid matrix to form a thrombin-containing liquid, where the hypotonic composition includes water, calcium, a blood component comprising platelets, and optionally a chelator. Calcium is present in the hypotonic composition in an amount greater than the amount of calcium that can be complexed by the chelator. Thrombin-containing liquid is then separated from the hypotonic composition and can be applied to the site on the subject to form a clot, for example, by combination with fibrinogen.Type: ApplicationFiled: October 25, 2013Publication date: June 5, 2014Applicant: Biomet Biologics, LLCInventors: Randel Dorian, Richard W. Storrs, Michael D. Leach
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Publication number: 20140091048Abstract: A separator system operable to use centrifugation to fractionate a multiple component material, such as a suspension including blood, comprises a buoy. The buoy can be carried in a separation container and has a tuned density that is configured to reach an equilibrium position in the multiple component material. A guide surface is carried on a buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.Type: ApplicationFiled: December 2, 2013Publication date: April 3, 2014Applicants: Hanuman LLC, Biomet Biologics, LLCInventors: Michael D. LEACH, Randel DORIAN, Jacy C. HOEPPNER
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Patent number: 8596470Abstract: A separator system operable to use centrifugation to fractionate a multiple component material, such as a suspension including blood, comprises a buoy. The buoy can be carried in a separation container and has a tuned density that is configured to reach an equilibrium position in the multiple component material. A guide surface is carried on a buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.Type: GrantFiled: February 20, 2012Date of Patent: December 3, 2013Assignees: Hanuman, LLC, Biomet Biologics, LLCInventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
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Publication number: 20130294983Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.Type: ApplicationFiled: July 1, 2013Publication date: November 7, 2013Inventors: Randel DORIAN, Richard W. STORRS, Scott R. KING
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Patent number: 8474630Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.Type: GrantFiled: May 25, 2012Date of Patent: July 2, 2013Assignee: Hanuman, LLCInventors: Randel Dorian, Scott R. King, Richard Wood Storrs
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Patent number: 8337711Abstract: Disclosed is a system to separate, enrich, and/or purify a cellular population from a biological tissue, such as a tissue sample. For example, an adipose tissue sample can be acquired and disrupted. The disrupted tissue sample can then be separated and purified. The separated components can include multipotent, pluripotent, or other cell populations.Type: GrantFiled: February 27, 2009Date of Patent: December 25, 2012Assignee: Biomet Biologics, LLCInventors: Randel Dorian, Michael D. Leach, Richard W. Storrs, Jason Chavarria