Patents by Inventor Randy Mrsny

Randy Mrsny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF TIGHT JUNCTION PERMEABILITY
    Publication number: 20230234987
    Abstract: The invention relates to compounds capable of modulating the permeability of junctions between epithelial cells, and their use to facilitate delivery of substances such as therapeutic and diagnostic agents across epithelial surfaces.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 27, 2023
    Applicant: The University of Bath
    Inventors: Randy MRSNY, Alistair TAVERNER, Khaled ALMANSOUR
  • Mucosal delivery of therapeutic molecules, proteins, or particles coupled to ceramide lipids
    Patent number: 10806793
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: October 20, 2020
    Assignee: Children's Medical Center Corporation
    Inventors: Wayne I. Lencer, Daniel J F Chinnapen, Randy Mrsny
  • Mucosal delivery of therapeutic molecules, proteins, or particles coupled to ceramide lipids
    Patent number: 10765757
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: September 8, 2020
    Assignee: Children's Medical Center Corporation
    Inventors: Wayne I. Lencer, Daniel J F Chinnapen, Randy Mrsny
  • MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS
    Publication number: 20180333499
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Application
    Filed: November 20, 2017
    Publication date: November 22, 2018
    Inventors: WAYNE I. LENCER, DANIEL JF CHINNAPEN, RANDY MRSNY
  • MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS
    Publication number: 20180133332
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Application
    Filed: November 20, 2017
    Publication date: May 17, 2018
    Inventors: WAYNE I. LENCER, DANIEL JF CHINNAPEN, RANDY MRSNY
  • MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS
    Publication number: 20170095563
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Application
    Filed: September 2, 2016
    Publication date: April 6, 2017
    Applicant: Children's Medical Center Corporation
    Inventors: Wayne I. Lencer, Daniel JF Chinnapen, Randy Mrsny
  • Mucosal delivery of therapeutic molecules, proteins, or particles coupled to ceramide lipids
    Patent number: 9457097
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: October 4, 2016
    Assignee: Children's Medical Corporation
    Inventors: Wayne I. Lencer, Daniel J F Chinnapen, Randy Mrsny
  • MUCOSAL DELIVERY OF THERAPEUTIC MOLECULES, PROTEINS, OR PARTICLES COUPLED TO CERAMIDE LIPIDS
    Publication number: 20120252727
    Abstract: Described herein are compositions and methods useful for allowing for the absorption (passage) of agents of interest, such as therapeutic agents, across epithelial and mucosal barriers and/or into certain subcellular compartments of the cell, such as the recycling endosome (RE), Golgi, and the endoplasmic reticulum (ER).
    Type: Application
    Filed: September 4, 2009
    Publication date: October 4, 2012
    Applicant: Children's Medical Center Corporation
    Inventors: Wayne I. Lencer, Daniel JF Chinnapen, Randy Mrsny
  • Compaction assay for assessment of respiratory disease therapy
    Publication number: 20050164334
    Abstract: A compaction assay measuring the viscoelasticity of sputum samples of patients subject to respiratory disease is provided. This assay is useful in determining the therapeutic efficacy of DNase, antibiotic and other respiratory disease treatments in improving lung function.
    Type: Application
    Filed: January 10, 2005
    Publication date: July 28, 2005
    Applicant: Genentech, Inc.
    Inventors: Ann Daugherty, Randy Mrsny, Thomas Patapoff