Abstract: A process for producing power including injecting a first heat transfer fluid through an injection well to a geothermally-heated formation that contains a second heat transfer fluid. The first heat transfer fluid may then be heated via indirect heat exchange in an interwell run fluidly connected to the injection well and disposed within the geothermally-heated formation. The heated first heat transfer fluid may then be recovered through a production well fluidly connected to the interwell run. Thermal energy contained in the recovered heated first heat transfer fluid may then be converted in a power production unit fluidly connected to the injection well and the production well. The interwell run, in some embodiments, may include multiple heat exchange tubes disposed within a perforated casing or drill pipe.