Patents by Inventor Ranga Nathan

Ranga Nathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for increasing yields of recombinant proteins
    Patent number: 5914390
    Abstract: Methods are disclosed for increasing the yields of recombinant proteins. Addition of one or more protective agents, such as a sulfated compound (including heparin, heparin sulfate, sodium dodecyl sulfate, and the like), hyaluronic acid or deoxycholate, to recombinant protein production processes is disclosed. Addition of protective agents to the recombinant production process results in increased yields of recombinant proteins.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: June 22, 1999
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Ranga Nathan, Henryk Cudny
  • Method and activin compositions for inducing bone growth
    Patent number: 5413989
    Abstract: Activin is administered systemically and locally to induce the growth of mature bone. Activin enhances the level of bone formation and the quality of the bone formed when administered locally with BMP or bone marrow. Administration of activin by subcutaneous route promotes systemic increase in the bone mass.
    Type: Grant
    Filed: May 3, 1993
    Date of Patent: May 9, 1995
    Assignee: Celtrix Pharmaceuticals, Inc.
    Inventors: Yasushi Ogawa, David K. Schmidt, Rosa Armstrong, Ranga Nathan, Andrea Y. Thompson, Saeid M. Seyedin
  • Method for inducing bone growth
    Patent number: 5208219
    Abstract: Activin is administered systemically and locally to induce the growth of mature bone. Activin enhances the level of bone formation and the quality of the bone formed when administered locally with BMP or bone marrow. Administration of activin by subcutaneous route promotes systemic increase in the bone mass.
    Type: Grant
    Filed: February 14, 1991
    Date of Patent: May 4, 1993
    Assignee: Celtrix Pharmaceuticals Inc.
    Inventors: Yasushi Ogawa, David K. Schmidt, Rosa Armstrong, Ranga Nathan, Andrea Y. Thompson, Saeid M. Seyedin
  • Inductive collagen-based bone repair preparations
    Patent number: 5001169
    Abstract: A composition suitable for inductive bone implants is disclosed. The composition comprises a purified form of osteogenic factor in admixture with a carrier having a percentage of mineral carrier. The resulting implants are sufficiently hypoimmunogenic to be effective when implanted in xenogeneic hosts.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: March 19, 1991
    Assignee: Collagen Corporation
    Inventors: Ranga Nathan, Saeid Seyedin, Karl Piez, Hanne Bentz
  • Inductive collagen-based bone repair preparations
    Patent number: 4888366
    Abstract: An improved process for the preparation of mineral/collagen/OF (osteogenic factor) inductive implants for bone repair utilizes drying, under ambient pressure conditions, a suspension of 75-95% mineral particles, 5-25% collagen, and an effective amount of OF, such as 0.5-4% partially purified OFE or its equivalent wherein the concentration of collagen in the suspension subjected to drying is 30-100 mg/ml. The resulting implants are improved. They are homogeneous in composition and have a high compressive modulus as well as containing OF in a biologically active and available form.
    Type: Grant
    Filed: September 25, 1987
    Date of Patent: December 19, 1989
    Assignee: Collagen Corporation
    Inventors: George Chu, Ranga Nathan, Saeid Seyedin
  • Injectable composition for inductive bone repair
    Patent number: 4863732
    Abstract: Aqueous suspensions of fibrillar atelopeptide collagen and osteogenic factor are effective injectable preparations for the repair of bone defects.
    Type: Grant
    Filed: December 16, 1987
    Date of Patent: September 5, 1989
    Assignee: Collagen Corporation
    Inventors: Ranga Nathan, Andrea Thompson, Saeid Seyedin
  • Inductive collagen based bone repair preparations
    Patent number: 4563350
    Abstract: A composition suitable for inductive bone implants is disclosed. The composition comprises a purified form of osteogenic factor in admixture with an carrier having a percentage of non-fibrillar collagen. The resulting implants are sufficiently hypo-immunogenic to be effective when implanted in xenogeneic hosts.
    Type: Grant
    Filed: October 24, 1984
    Date of Patent: January 7, 1986
    Assignee: Collagen Corporation
    Inventors: Ranga Nathan, Saied Seyedin, Karl Piez, Hanne Bentz