Patents by Inventor Raphael APONTE

Raphael APONTE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959086
    Abstract: The present invention refers to a recombinant chimeric nucleic acid molecule comprising a nucleic acid sequence encoding a dual transit peptide operably linked to a heterologous nucleic acid sequence encoding a polypeptide of interest which, when overexpressed in a plant, confers herbicide tolerance to said plant.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: April 16, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Tobias Seiser, Jill M. Paulik
  • Publication number: 20240026371
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: January 20, 2023
    Publication date: January 25, 2024
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Jill Marie Paulik, Chad Brommer
  • Patent number: 11879132
    Abstract: The present invention refers to a plant or plant part comprising a polynucleotide encoding a mutated PPO polypeptide, the expression of said polynucleotide confers to the plant or plant part tolerance to herbicides.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: January 23, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Dario Massa, Matthias Witschel, Tobias Seiser, Jill Marie Paulik
  • Patent number: 11866720
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: January 9, 2024
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Patent number: 11827896
    Abstract: The invention refers to plants comprising wild-type or mutated Alopecurus PPO enzymes, and methods of obtaining such plants. The present invention further refers to a method for controlling weeds at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated Alopecurus PPO enzyme which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: November 28, 2023
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Publication number: 20230345941
    Abstract: The present invention relates to phenylethers of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the phenylethers of formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one phenylether of formula (I) to act on plants, their seed and/or their habitat.
    Type: Application
    Filed: April 27, 2023
    Publication date: November 2, 2023
    Inventors: Matthias Witschel, Laetitia Souillart, Tobias Seiser, Trevor William Newton, Liliana Parra Rapado, Dario Massa, Raphael Aponte, Thomas Mietzner, Thomas Seitz
  • Publication number: 20230279420
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: August 4, 2022
    Publication date: September 7, 2023
    Inventors: Jens Lerchl, Stefan Tresch, Dario Massa, Tobias Seiser, Matthias Witschel, Raphael Aponte, Jill Marie Paulik, Chad Brommer
  • Publication number: 20230175005
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: October 24, 2022
    Publication date: June 8, 2023
    Inventors: Raphael Aponte, Tobias Seiser, Stefan Tresch, Peter Alexamder Bowerman, Liliana Parra Rapado, Matthias Witschel, Laetitia Souillart, Manuel Johannes, Thomas Mietzner, Jill Marie Paulik
  • Patent number: 11572571
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: February 7, 2023
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Jill Marie Paulik, Chad Brommer
  • Publication number: 20230036177
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: June 30, 2022
    Publication date: February 2, 2023
    Inventors: Raphael Aponte, Stefan Tresch, Dario Massa, Tobias Seiser, Thomas Mietzner
  • Patent number: 11479786
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: October 25, 2022
    Assignee: BASF SE
    Inventors: Raphael Aponte, Tobias Seiser, Stefan Tresch, Peter Alexander Bowerman, Liliana Parra Rapado, Matthias Witschel, Laetitia Souillart, Manuel Johannes, Thomas Mietzner, Jill Marie Paulik
  • Publication number: 20220315943
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: March 11, 2022
    Publication date: October 6, 2022
    Inventors: Johannes Hutzler, Raphael Aponte, Thomas Mietzner, Matthias Witschel, Anja Simon, Jens Lerchl, S Luke Mankin
  • Publication number: 20220315944
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: April 15, 2022
    Publication date: October 6, 2022
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Patent number: 11441154
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: September 13, 2022
    Assignee: BASF AGRO B.V.
    Inventors: Jens Lerchl, Stefan Tresch, Dario Massa, Tobias Seiser, Matthias Witschel, Raphael Aponte, Jill Marie Paulik, Chad Brommer
  • Patent number: 11306322
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: April 19, 2022
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Patent number: 11274313
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a benzoxazinone-derivative herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mutated PPO enzymes having a substitution at a position corresponding to position Arg128 of SEQ ID NO:2 and an amino acid substitution at a position corresponding to position Phe420 of SEQ ID NO:2, and methods of obtaining such plants.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: March 15, 2022
    Assignee: BASF AGRO B.V.
    Inventors: Johannes Hutzler, Raphael Aponte, Thomas Mietzner, Matthias Witschel, Anja Simon, Jens Lerchl, Stefan Tresch, S. Luke Mankin
  • Patent number: 11247980
    Abstract: The present invention relates to uracilpyridines of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the uracilpyryidines of the formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one urycilpyridine of the formula (I) to act on plants, their seed and/or their habitat.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: February 15, 2022
    Assignee: BASF SE
    Inventors: Tobias Seiser, Matthias Witschel, Manuel Johannes, Dario Massa, Liliana Parra Rapado, Raphael Aponte, Thomas Mietzner, Trevor William Newton, Thomas Seitz, Richard R. Evans, Andreas Landes
  • Publication number: 20210380999
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type or a mutated protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Application
    Filed: April 19, 2021
    Publication date: December 9, 2021
    Inventors: Raphael Aponte, Stefan Tresch, Matthias Witschel, Jens Lerchl, Dario Massa, Tobias Seiser, Thomas Mietzner, Jill Marie Paulik, Chad Brommer
  • Patent number: 11185075
    Abstract: The present invention relates to phenyltriazolinones of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the uracilpyryidines of the formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one urycilpyridine of the formula (I) to act on plants, their seed and/or their habitat.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: November 30, 2021
    Assignee: BASF SE
    Inventors: Tobias Seiser, Manuel Johannes, Matthias Witschel, Liliana Parra Rapado, Raphael Aponte, Thomas Mietzner, Dario Massa, Thomas Seitz, Peter Dombo, Andreas Landes, Stefan Tresch, Trevor William Newton
  • Patent number: 11149030
    Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding protoporphyrinogen oxidase (PPO) which is resistant or tolerant to a PPO-inhibiting herbicide by applying to said site an effective amount of said herbicide. The invention further refers to plants comprising wild-type or mutated PPO enzymes, and methods of obtaining such plants.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: October 19, 2021
    Assignee: BASF AGRO B.V.
    Inventors: Raphael Aponte, Stefan Tresch, Liliana Parra Rapado, Tobias Seiser, Jill Marie Paulik, Matthias Witschel