Patents by Inventor Raphael C. Wong
Raphael C. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7981382Abstract: A device for collecting, testing and storing fluids includes a container and a removable cap. Body fluids, such as urine, are collected in the container. The cap defines a test strip holder that receives one or more drug test strips and an adulteration strip. An opening defined through a bottom of the cap provides fluid communication between the container and the cap. When tilted, fluid from the container enters the cap through the hole. A variety of plugs may be employed to block the opening and thereby prevent fluid communication between the container and the cap after fluid has entered the cap. The remaining uncontaminated and untested body fluid is stored in the container and thus made available for further confirmation testing. Associated methods for collecting, testing and storing fluids with a single device are also provided. A method of manufacturing the foregoing test device is also provided.Type: GrantFiled: June 14, 2005Date of Patent: July 19, 2011Assignee: Branan Medical CorporationInventors: Raphael C. Wong, Ker-Kong Tung
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Patent number: 6875185Abstract: A lateral flow immunoassay contact chemical test device and method integrates sample collection, prescreen testing, and confirmation sample collecting and storing with a single device and a minimum of steps. While particularly advantageously used with an oral fluid sample absorbed directly from a person's mouth, (in which constant monitoring of a collection process is made possible), the test device may be used with any of a variety of sample fluids. Prescreen testing and confirmation testing are performed on a single sample. Prescreen testing is performed by a lateral flow assay. The sample collection pad is subsequently separated from the wicking path to prevent continued migration from, and backflow into the sample collection pad, so that the confirmation sample is preserved in the sample collection pad. A multitude of antigens can be detected with a single device.Type: GrantFiled: July 29, 2002Date of Patent: April 5, 2005Assignee: Branan Medical CorporationInventors: Raphael C. Wong, Dequn Wang
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Patent number: 6818452Abstract: A test strip assembly for detecting the presence of a substance in liquid sample comprises a contact detection pad in communication with a reagent-free absorbent strip. The absorbent strip receives the liquid sample and communicates it to the contact detection pad via lateral flow. The absorbent strip and contact detection pad are adhered to a support. A liquid impermeable pad is disposed adjacent to and spaced apart from the contact detection pad to prevent any further travel of the sample. Further add-on assemblies may be coupled to the base test strip assembly. The test strip assembly may be disposed in a housing along with a drug test strip to form a device that performs multiple types of tests. Methods for assaying and manufacturing are also provided.Type: GrantFiled: April 23, 2001Date of Patent: November 16, 2004Assignee: Branan Medical Corp.Inventor: Raphael C. Wong
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Publication number: 20040019301Abstract: A lateral flow immunoassay contact chemical test device and method integrates sample collection, prescreen testing, and confirmation sample collecting and storing with a single device and a minimum of steps. While particularly advantageously used with an oral fluid sample absorbed directly from a person's mouth, (in which constant monitoring of a collection process is made possible), the test device may be used with any of a variety of sample fluids. Prescreen testing and confirmation testing are performed on a single sample. Prescreen testing is performed by a lateral flow assay. The sample collection pad is subsequently separated from the wicking path to prevent continued migration from, and backflow into the sample collection pad, so that the confirmation sample is preserved in the sample collection pad. A multitude of antigens can be detected with a single device.Type: ApplicationFiled: July 29, 2002Publication date: January 29, 2004Inventors: Raphael C. Wong, Dequn Wang
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Patent number: 6627152Abstract: A fluid testing apparatus comprises a vessel for collecting a fluid, a removable cap secured to the top of the vessel, and a movable carrier to transport a portion of the fluid in the vessel to test strips disposed within the cap. The test strips are disposed in cavities of the cap. One end portion of each test strip exits through an exit port on the bottom side of the cap. A rim on the bottom side of the cap surrounds the protruding end portions of the test strips. The movable carrier is movable between a retrieving position to collect the fluid and a testing position where the retrieved fluid is brought into contact with the protruding ends of the test strips. A spring bias mechanism causes the carrier to move toward the closed, testing position by default. In the testing position, the carrier's receptacle forms a seal with the surrounding rim and the bottom side of the cap to prevent the carried portion of the fluid from contacting the remaining, non-tested fluid in the vessel.Type: GrantFiled: July 20, 2000Date of Patent: September 30, 2003Assignee: Branan Medical Corp.Inventor: Raphael C. Wong
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Publication number: 20020155028Abstract: A test strip assembly for detecting the presence of a substance in liquid sample comprises a contact detection pad in communication with a reagent-free absorbent strip. The absorbent strip receives the liquid sample and communicates it to the contact detection pad via lateral flow. The absorbent strip and contact detection pad are adhered to a support. A liquid impermeable pad is disposed adjacent to and spaced apart from the contact detection pad to prevent any further travel of the sample. Further add-on assemblies may be coupled to the base test strip assembly. The test strip assembly may be disposed in a housing along with a drug test strip to form a device that performs multiple types of tests. Methods for assaying and manufacturing are also provided.Type: ApplicationFiled: April 23, 2001Publication date: October 24, 2002Inventor: Raphael C. Wong
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Publication number: 20020132267Abstract: A combination drug test and adulterant test device comprises a container having an adulterant test strip and a drug test strip. The strips are held in place and kept physically and fluidly separate from each other by a combination of recesses, ribs, and uneven surfaces. Apertures are formed in the upper portion of the body for providing access to the strips to enable portions of the sample to be disposed. Windows are formed in the upper portion for viewing the indicator portions of the drug test strips. A method for manufacturing drug test strips is also provided.Type: ApplicationFiled: March 16, 2001Publication date: September 19, 2002Inventor: Raphael C. Wong
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Patent number: 5219529Abstract: A cartridge includes a male end, a female end and an internal chamber defined by a filter adjacent the male and female ends. The cartridge is specifically designed to be stackable with additional cartridges, as the male end of one cartridge can close the female end of a different cartridge. The cartridges are useful in holding samples for analysis.Type: GrantFiled: September 14, 1992Date of Patent: June 15, 1993Assignee: UniSyn Technologies, Inc.Inventors: That T. Ngo, Raphael C. Wong
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Patent number: 4977077Abstract: The presence of an antigenic analyte ligand in a liquid sample is determined by (1) mixing the sample with a fluorescently labeled ligand immunologically complexed onto a solid phase supported antibody capable of exchanging the fluorescently labeled ligand with the analyte ligand in the sample and (2) measuring the fluorescence of the resulting liquid phase without measuring the fluorescence of the resulting solid phase and without separating the resulting solid phase from the resulting liquid phase.Type: GrantFiled: April 25, 1988Date of Patent: December 11, 1990Assignee: Bioprobe InternationalInventors: That T. Ngo, Raphael C. Wong
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Patent number: 4892710Abstract: A cartridge assembly useful as a sampling or test device includes a cartridge and a closure tubing adapted to close either or both ends of the cartridge and to serve as a conduit for liquids eluted from the cartridge.Type: GrantFiled: July 7, 1987Date of Patent: January 9, 1990Assignee: Bioprobe International, Inc.Inventors: Raphael C. Wong, That T. Ngo
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Patent number: 4292425Abstract: Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to valproic acid and .beta.-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compounds used to prepare such reagents, including valproic acid immunogen conjugates and intermediates in the synthesis of such immunogen conjugates and .beta.-galactosyl-umbelliferone-labeled conjugates.Type: GrantFiled: April 14, 1980Date of Patent: September 29, 1981Assignee: Miles Laboratories, Inc.Inventors: Robert T. Buckler, John F. Burd, Raphael C. Wong
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Patent number: 4261974Abstract: Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to valproic acid and .beta.-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compounds used to prepare such reagents, including valproic acid immunogen conjugates and intermediates in the synthesis of such immunogen conjugates and .beta.-galactosyl-umbelliferone-labeled conjugates.Type: GrantFiled: November 13, 1979Date of Patent: April 14, 1981Assignee: Miles Laboratories, Inc.Inventors: Robert T. Buckler, John F. Burd, Raphael C. Wong