Abstract: A fluid flow control valve utilizes a ball which is rotated about an axis greater than 0 degrees and less than 90 degrees to the direction of fluid flow. The ball member utilizes a fluid flow conduit through its center with a flat surface disposed at an angle to the fluid flow conduit. When in the closed position, the flat surface is disposed flush with a valve face on one port of the valve. The ball is also disposed so that its center is less than a radius length from the surface defined by the valve face.

Abstract: Apparatus for performing binder-substrate processing of clinical substances is disclosed. An operating head is provided which includes an array of upwardly opening receptacles each having a closed bottom. A temperature control element is located in the operating head proximate the receptacles. The operating head also includes a manifold having an influx chamber, an efflux chamber and a plurality of hollow prongs emanating from the influx chamber and through the efflux chamber. The prongs extend downwardly into respective of the receptacles to provide fluid communication between the influx chamber and the interior of the receptacles through the prongs. The efflux chamber is in fluid communication with the open ends of the receptacles to drain fluid therefrom. A solid phase binder is located in the bottoms of the respective receptacles, and may be coated on solid phase elements located in the receptacles or on the receptacles themselves.