Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: An electronic valve is placed in line with a casing in a well. The electronic valve includes a housing having plural ports that are blocked; a valve configured to initiate unblocking of the plural ports to allow fluid communication between the bore of the housing and an outside of the housing; and a deformable seat device having a body placed inside of the bore of the housing. The deformable seat device is configured to have a given diameter D3 for at least one of first and second ends of the body when the plural ports are blocked, and a smaller diameter when the plural ports are unblocked.

Abstract: A setting tool for setting a plug in a well, the setting tool including a housing extending along a longitudinal axis X and having a bore; a sleeve extending along the longitudinal axis of the housing, and located within the bore of the housing; and a holding mechanism located within the sleeve and configured to hold a ball within the sleeve. The holding mechanism is configured to release the ball upon receiving a signal.

Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: An electronic valve is placed in line with a casing in a well. The electronic valve includes a housing having plural ports that are blocked; a valve configured to initiate unblocking of the plural ports to allow fluid communication between the bore of the housing and an outside of the housing; and a deformable seat device having a body placed inside of the bore of the housing. The deformable seat device is configured to have a given diameter D3 for at least one of first and second ends of the body when the plural ports are blocked, and a smaller diameter when the plural ports are unblocked.

Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: An air lock device for sealing a casing located inside a well, the air lock device including a body having a bore and configured to be attached with each end to the casing; a moving element located inside the bore; and a blocking element connected to the moving element, the blocking element preventing a fluid to pass through the bore of the body. The moving element forms an inner chamber with the body in which the blocking element is trapped after the blocking element is punctured by the moving element.

Abstract: An air lock device for sealing a casing located inside a well, the air lock device including a body having a bore and configured to be attached with each end to the casing; a moving element located inside the bore; and a blocking element connected to the moving element, the blocking element preventing a fluid to pass through the bore of the body. The moving element forms an inner chamber with the body in which the blocking element is trapped after the blocking element is punctured by the moving element.

Abstract: Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.

Abstract: A downhole tool, such as a sliding sleeve, deploys on a tubing string in a borehole. The tool has a housing with an internal bore and at least one port communicating outside the housing. An insert disposed in the bore can move from a closed position to an opened position relative to the port so fluid can be communicated to the borehole. A burst band disposed outside the housing at the port can break away from the housing in response to a particular pressure level communicated through the open port. In particular, the insert can have a seat that engages a deployed plug or ball. The insert shifts open when a first level of applied pressure against the seated ball shears the insert free. This can give a first indication that the insert has moved open. Then, a second level of pressure can be detected when the burst band breaks as a second indication that the insert is opened.

Abstract: A sliding sleeve opens with a deployed ball. The sleeve has a seat disposed in the housing, and the seat has segments biased outward from one another with a C-ring or other biasing element. Initially, the seat has an expanded state in the sliding sleeve so that the seats segments expand outward against the housing's bore. When an appropriately sized ball is deployed downhole, the ball engages the expanded seat. Fluid pressure applied against the seated ball moves the seat into the inner sleeve's bore. As this occurs, the seat contracts, which increases the engagement area of the seat with the ball. Eventually, the seat reaches the shoulder in the inner sleeve so that pressure applied against the seated ball now moves the inner sleeve in the housing to open the sliding sleeve's flow port.

Abstract: A downhole tool, such as a sliding sleeve, deploys on a tubing string in a borehole. The tool has a housing with an internal bore and at least one port communicating outside the housing. An insert disposed in the bore can move from a closed position to an opened position relative to the port so fluid can be communicated to the borehole. A burst band disposed outside the housing at the port can break away from the housing in response to a particular pressure level communicated through the open port. In particular, the insert can have a seat that engages a deployed plug or ball. The insert shifts open when a first level of applied pressure against the seated ball shears the insert free. This can give a first indication that the insert has moved open. Then, a second level of pressure can be detected when the burst band breaks as a second indication that the insert is opened.

Abstract: A sliding sleeve opens with a deployed ball. The sleeve has a seat disposed in the housing, and the seat has segments biased outward from one another with a C-ring or other biasing element. Initially, the seat has an expanded state in the sliding sleeve so that the seats segments expand outward against the housing's bore. When an appropriately sized ball is deployed downhole, the ball engages the expanded seat. Fluid pressure applied against the seated ball moves the seat into the inner sleeve's bore. As this occurs, the seat contracts, which increases the engagement area of the seat with the ball. Eventually, the seat reaches the shoulder in the inner sleeve so that pressure applied against the seated ball now moves the inner sleeve in the housing to open the sliding sleeve's flow port.