Patents by Inventor Raymond Wai Yin Sun

Raymond Wai Yin Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition containing cyclometalated N-heterocyclic carbene complexes for cancer treatment
    Patent number: 9822139
    Abstract: The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: November 21, 2017
    Assignee: THE UNIVERSITY OF HONG KONG
    Inventors: Chi Ming Che, Raymond Wai-Yin Sun, Lok Fung Chow, Jing Yan
  • PHARMACEUTICAL COMPOSITION CONTAINING CYCLOMETALATED N-HETEROCYCLIC CARBENE COMPLEXES FOR CANCER TREATMENT
    Publication number: 20130324511
    Abstract: The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
    Type: Application
    Filed: August 7, 2013
    Publication date: December 5, 2013
    Applicant: THE UNIVERSITY OF HONG KONG
    Inventors: Chi Ming Che, Raymond Wai-Yin Sun, Lok Fung Chow, Jing Yan
  • Hydroxy-substituted gold(III) porphyrin complexes as histone deacetylase inhibitors
    Patent number: 8563712
    Abstract: A method for treatment of cancer by inhibiting the activity of histone deacetylase, comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of a gold(III) complex having the structural formula of or a pharmaceutically acceptable salt thereof, wherein: —R is selected from the group consisting of —OH, —CH2OH, C2H4OH, —C3H6OH or —C4H8OH; and X is independently a pharmaceutically acceptable counter-ion.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: October 22, 2013
    Assignee: The University of Hong Kong
    Inventors: Chi Ming Che, Yu Wang, Raymond Wai Yin Sun, Kim Hei-Man Chow
  • Pharmaceutical composition containing cyclometalated N-heterocyclic carbene complexes for cancer treatment
    Patent number: 8530659
    Abstract: The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: September 10, 2013
    Assignee: The University of Hong Kong
    Inventors: Chi Ming Che, Raymond Wai-Yin Sun, Lok Fung Chow, Jing Yan
  • HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20110098263
    Abstract: A method for treatment of cancer by inhibiting the activity of histone deacetylase, comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of a gold(III) complex having the structural formula of or a pharmaceutically acceptable salt thereof, wherein: —R is selected from the group consisting of —OH, —CH2OH, C2H4OH, —C3H6OH or —C4H8OH; and X is independently a pharmaceutically acceptable counter-ion.
    Type: Application
    Filed: October 27, 2010
    Publication date: April 28, 2011
    Inventors: Chi Ming Che, Yu Wang, Raymond Wai Yin Sun, Kim Hei-Man Chow
  • PHARMACEUTICAL COMPOSITION CONTAINING CYCLOMETALATED N-HETEROCYCLIC CARBENE COMPLEXES FOR CANCER TREATMENT
    Publication number: 20110098264
    Abstract: The present disclosure is related to a pharmaceutical composition for treatment of cancer comprising a cyclometalated N-heterocyclic carbene complex. The cyclometalated N-heterocyclic carbene complex contains a gold(III) or a platinum(II) atom. The pharmaceutical composition possesses anti-cancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of topoisomerase and/or poisoning of topoisomerase.
    Type: Application
    Filed: October 27, 2010
    Publication date: April 28, 2011
    Applicant: THE UNIVERSITY OF HONG KONG
    Inventors: Chi Ming Che, Raymond Wai-Yin Sun, Lok Fung Chow, Jing Yan
  • Pharmaceutical composition having a ruthenium oxalato compound and method of using the same
    Patent number: 7648977
    Abstract: The present invention relates to a pharmaceutical composition comprising one or more of the following ruthenium oxalato compounds I, II, III and IV as an active ingredient. The pharmaceutical composition can be used for the treatment of viral-infected patients or prophylactic treatment of patients at risk from viral infection.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: January 19, 2010
    Assignee: The University of Hong Kong
    Inventors: Chi-Ming Che, Raymond Wai-Yin Sun, Ella Lai-Ming Wong
  • Anti-cancer phosphine containing [Au(CNC)L] complexes and derivatives thereof and methods for treating cancer using such compositions
    Patent number: 7632827
    Abstract: Gold(III) phosphine complexes [Aum(CNC)mL]n+ (where HCNCH=2,6-diphenylpyridine) and their use as anti-tumor agents are disclosed. Notable results for the appearance of new potential anti-tumor application of these gold(III) complexes are reported. The described complexes show promising cytotoxic properties toward cancer cells in both in vitro and in vivo studies.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: December 15, 2009
    Assignee: The University of Hong Kong
    Inventors: Chi Ming Che, Raymond Wai Yin Sun, Zhen Fan Yang, Carrie Ka Lei Li
  • ANTI-CANCER PHOSPHINE CONTAINING [AuIIIm(CNC)mL]n+ COMPLEXES AND DERIVATIVES THEREOF AND METHODS FOR TREATING CANCER USING SUCH COMPOSITIONS
    Publication number: 20080166429
    Abstract: Gold(III)phosphine complexes [Aum(CNC)mL]n+ (where HCNCH=2,6-diphenylpyridine) and their use as anti-tumor agents are disclosed. Notable results for the appearance of new potential anti-tumor application of these gold(III) complexes are reported. The described complexes show promising cytotoxic properties toward cancer cells in both in vitro and in vivo studies.
    Type: Application
    Filed: December 20, 2007
    Publication date: July 10, 2008
    Inventors: Chi Ming Che, Raymond Wai Yin Sun, Zhen Fan Yang, Carrie Ka Lei Li
  • Pharmaceutical composition having a ruthenium oxalato compound and method of using the same
    Publication number: 20070105952
    Abstract: The present invention relates to a pharmaceutical composition comprising one or more of the following ruthenium oxalato compounds I, II, III and IV as an active ingredient. The pharmaceutical composition can be used for the treatment of viral-infected patients or prophylactic treatment of patients at risk from viral infection.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 10, 2007
    Inventors: Chi-Ming Che, Raymond Wai-Yin Sun, Ella Lai-Ming Wong