Patents by Inventor Rebecca Elizabeth Brown

Rebecca Elizabeth Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,3-Substituted Fused Pyrimidin -4 (3H)-Ones as VR1 Antagonists
    Publication number: 20110152242
    Abstract: A compound of formula (I), wherein W is formula (1); A is a benzene ring, a fÊve-membered heteroaromatic ring containing 1, 2 or 3 heteroatoms independently chosen from O, N and S, providing that no more than one O or S atom is present, or a six-membered heteroaromatic ring containing 1, 2 or 3 N atoms; n is zero, one, two or three; when n is zero or one, V is CH2; when n is two or three, V is CH2, O or NR5; when V is CH2, the bond formed by V and an adjacent carbon ring atom is optionally fused to a phenyl ring, a five-membered heteroaromatic ring containing 1, 2 or 3 heteroatoms independently chosen from O, N and S, providing that no more than one O or S is present, or a six-membered heteroaromatic ring containing 1, 2 or 3 N atoms; the ring being optionally substituted by one or more R1 groups; and R7 and R8 are independently hydrogen, hydroxy, halogen or C1-4alkyl; Z is a phenyl ring, a five-membered heteroaromatic ring containing one, two, three or four heteroatoms independently chosen from O, N or S, at
    Type: Application
    Filed: March 21, 2006
    Publication date: June 23, 2011
    Inventors: Tracy Bayliss, Rebecca Elizabeth Brown, Gregory John Hollingworth, Brian A. Jones, Christopher Richard Moyes, Lauren Rogers
  • 2,3 Substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilliod-1receptor (VR1)
    Publication number: 20090298856
    Abstract: The use of a compound of formula (I): for the manufacture of a medicament for the treatment of conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1, also known as TRPV1).
    Type: Application
    Filed: May 10, 2006
    Publication date: December 3, 2009
    Inventor: Rebecca Elizabeth Brown
  • 2,3-Substituted fused bicyclic pyrimidin-4(3H)-ones which modulating the function of the vanilloid -1 receptor (VR1)
    Publication number: 20090233947
    Abstract: Compounds of formula (I) which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1, also known as TRPV1).
    Type: Application
    Filed: May 10, 2006
    Publication date: September 17, 2009
    Inventors: Tracy Bayliss, Rebecca Elizabeth Brown, Gregory John HollingWorth, A. Brian Jones
  • Heteroaromatic urea derivatives as VR-1 receptor modulators for treating pain
    Patent number: 7285563
    Abstract: The present invention provides compounds of formula (I); pharmaceutically acceptable salts and N-oxides thereof in which A, B, D and E are C or N with the proviso that one or more are N, R1, R2, R3, R4, R5 and R6 are simple substituents, n is 0-3 and y is an aryl, heteroaryl, carbocyclyl or fused-carbocyclyl group; as VR-1 antagonists for treating conditions or diseases in which pain and/or inflammation predominates; the use of the same for manufacturing medicaments, pharmaceutical compositions comprising them and methods of treatment utilizing them
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: October 23, 2007
    Inventors: Rebecca Elizabeth Brown, Victoria Alexandra Doughty, Gregory John Hollingworth, A. Brian Jones, Matthew John Lindon, Christopher Richard Moyes, Lauren Rogers