Abstract: The invention relates to a device for detecting a sample in a longitudinal sample container (10), comprising a sample container holder (30) for holding the sample container in a housing. Said sample container holder comprises a side viewing window in the region of at least one longitudinal side of the sample container, and a front viewing window (35) in the region at least one front side of the sample container. Said device also comprises a first illumination arrangement for illuminating the sample container through the front viewing window, a second illumination arrangement for illuminating the sample container through the side viewing window, and an imaging photodetector for detecting a first image of the sample illuminated by means of the first illumination arrangement, and a second image of the sample illuminated by means of the second illumination arrangement. Said detection takes place through the side viewing window.

Abstract: The invention relates to a method for determining the viability of cells in cell cultures, said method comprising the steps of: coloring the sample with a dye which can penetrate into individual cells depending on the viability of the latter, determining the proportions of cells which are colored to differing extents. The invention is distinguished by virtue of the fact that a cell suspension of the colored cells is centrifuged as a sample in a sample vessel (10) until the solid content present in the sample has settled as a compressed cell cake (13), and, in order to determine the proportions, the volumes of differently colored sections (131, 132, 133) of the compressed cell cake (13) are determined as a measure of the proportions of cells of different viability.

Abstract: An optical sensor is provided with reduced sensitivity toward external light influences, fluorophores, and radiation, more particularly gamma radiation. The sensor is suitable for determining at least one parameter in a medium. The sensor has a matrix that contains a fluorescent dye. The matrix is supported by a transparent substrate and has a precious metal layer on the side facing the medium. The precious metal layer provides protection against photobleaching and radiation. The optical sensor is suitable for implementation in containers and laboratory products that are sterilized by gamma radiation, such as disposable bioreactors.

Abstract: A storage and/or reaction container system for fluids, includes a container and an electronic documentation device connected to the container. The documentation device further includes a timing device for capturing a point in time, at least one sensor, at least one input device for capturing inputs, and a storage device to store for readout at least one measured value captured by the at least one sensor device and/or an input captured by the at least one input device. The at least one measured value and/or the at least one input is associated by the timing device with the point in time of the capture.

Abstract: Device for fastening a sensor on containers with a flexible container wall, in particular mixing bags, comprising a sensor support which is fitted with a sensor, bears against an inner wall of the container wall at least with a rear subsurface averted from the sensor, and is guided with a central piece through an opening in the container wall in which the sensor support is fixed on the container wall by a clamping part which can be connected to the central piece, in which the container wall is clamped between the rear subsurface of the sensor support and on a bearing surface, facing an outer wall of the container, of the clamping part, and in which the rear subsurface bears sealingly against the inner wall of the container wall. The sensor support can also have an electronic or optical transmit unit which is connected to the sensor, in which case the transmit unit communicates in a wireless fashion with a receive unit arranged outside the container.

Abstract: An incubator (1) with an incubation chamber (2), a shaking device (4) which can be driven by a drive unit and which is used to shake receptacles (5) that can be placed in the incubation chamber (2) and that contain cell cultures, and a device chamber (3) which adjoins the incubation chamber (2) and which accommodates at least parts of the shaking device (4) protruding into the incubation chamber (2), wherein the shaking device (4) has a base plate (8) which seals off the incubation chamber (2) relative to the device chamber (4) and which, on its inner face (9) directed toward the incubation chamber (2), has a shaking table (11) that can be moved in a horizontal plane by a drive arm (10), wherein a motor (34) is arranged on the outer face (37) of the base plate (8) directed away from the inner face (9), which motor (34) drives a drive shaft (14) that is rotatably mounted in the base plate (8) and that is operatively connected to the drive arm (10).

Abstract: A connector (10) is provided for sterile connection to a complementary connector (12). The connector (10) has a housing (14) with an engagement device (16) to engage a complementary engagement device (18) of the complementary connector (12) along an engagement direction (44). The connector (10) is displaceable relative to the complementary connector (12) along the engagement direction (44) after the engagement device (16) engages the complementary engagement device (18). The housing (14) has a feed-through opening (24) for receiving a sensor (34) and a cover (22). The cover (22) is displaced relative to the connector (10) along the engagement direction (44) to close the feed-through opening (24) in a sterile manner. The connector (10) also has a sterile sensor (34) that is movable along a sensor displacement direction (52) that differs from the engagement direction (44).

Abstract: Bioreactor having at least one transparent window (5, 12, 13), the inner side (6) of which can be touched by a medium that can be arranged in a reactor interior (3), wherein the window (5, 12, 13) has a photocatalytic coating (7) on its inner side (6) facing the reactor interior (3), which coating can be activated by at least one light source from the outer side remote from the inner side (6).

Abstract: Device for fastening a sensor on containers with a flexible container wall, in particular mixing bags, comprising a sensor support which is fitted with a sensor, bears against an inner wall of the container wall at least with a rear subsurface averted from the sensor, and is guided with a central piece through an opening in the container wall in which the sensor support is fixed on the container wall by a clamping part which can be connected to the central piece, in which the container wall is clamped between the rear subsurface of the sensor support and on a bearing surface, facing an outer wall of the container, of the clamping part, and in which the rear subsurface bears sealingly against the inner wall of the container wall. The sensor support can also have an electronic or optical transmit unit which is connected to the sensor, in which case the transmit unit communicates in a wireless fashion with a receive unit arranged outside the container.

Abstract: Container system with one container (1) with a flexible partition, in particular a disposable container, that can be inserted into a carrying container that supports its lateral container partition (10) and in which liquid medium (8) that has been poured in can be mixed, with the carrying container (4) featuring at least one baffle (15, 15?, 15?, 15??) on the internal support partition (11) that forms the lateral container partition.

Abstract: The invention relates to a method for determining the viability of cells in cell cultures, said method comprising the steps of: colouring the sample with a dye which can penetrate into individual cells depending on the viability of the latter, determining the proportions of cells which are coloured to differing extents. The invention is distinguished by virtue of the fact that a cell suspension of the coloured cells is centrifuged as a sample in a sample vessel (10) until the solid content present in the sample has settled as a compressed cell cake (13), and, in order to determine the proportions, the volumes of differently coloured sections (131, 132, 133) of the compressed cell cake (13) are determined as a measure of the proportions of cells of different viability.

Abstract: Device for fastening a sensor on containers with a flexible container wall, in particular mixing bags, comprising a sensor support which is fitted with a sensor, bears against an inner wall of the container wall at least with a rear subsurface averted from the sensor, and is guided with a central piece through an opening in the container wall in which the sensor support is fixed on the container wall by a clamping part which can be connected to the central piece, in which the container wall is clamped between the rear subsurface of the sensor support and on a bearing surface, facing an outer wall of the container, of the clamping part, and in which the rear subsurface bears sealingly against the inner wall of the container wall. The sensor support can also have an electronic or optical transmit unit which is connected to the sensor, in which case the transmit unit communicates in a wireless fashion with a receive unit arranged outside the container.

Abstract: The invention relates to a device for agitating media (1), which are located on a platform (3). Said device consists of a housing (2) with an agitation mechanism, which is used to agitate the platform (3) and at least one sensor (4, 5), which is connected to a control unit (7) that is equipped with an electronic sensor system (6). According to the invention, the sensor(s) (4, 5) and the electronic sensor system (6) are located on the platform (3) and communicate in a wireless manner with the fixed control unit (7).

Abstract: Container and method for the mixing of media, in particular as a disposable container, which has at least one closable opening for the introduction and/or removal of the media and has a first sensor for measurement of at least one parameter of the mixture, in which at least one second sensor for measurement of the same parameter is arranged at a distance from the first sensor.

Abstract: The invention relates to a device for detecting a sample in a longitudinal sample container (10), comprising a sample container holder (30) for holding the sample container in a housing. Said sample container holder comprises a side viewing window in the region of at least one longitudinal side of the sample container, and a front viewing window (35) in the region at least one front side of the sample container. Said device also comprises a first illumination arrangement for illuminating the sample container through the front viewing window, a second illumination arrangement for illuminating the sample container through the side viewing window, and an imaging photodetector for detecting a first image of the sample illuminated by means of the first illumination arrangement, and a second image of the sample illuminated by means of the second illumination arrangement. Said detection takes place through the side viewing window.

Abstract: The invention relates to a disposable bioreactor comprising a reversible, externally attachable sensor arrangement for measuring a physical variable of a contained medium. A sensor adapter (28) for receiving an electronic sensor arrangement (34, 38; 42; 44a, 44b, 46, 48) interacting with the medium cross-flowing the peripheral lines (14, 16, 18), by means of an inner delimiting surface (32a, 32b; 42; 44a, 44b, 46, 48) of the sensor adapter, is integrated into at least one of the peripheral lines (14, 16, 18) of the bioreactor which is used to supply or discharge the medium. Said sensor adapter (28) is mounted on the peripheral line (14, 16, 18) as an insert extending the peripheral line (14, 16, 18) and which can be cross-flown by the contained medium.

Abstract: The invention relates to a device for carrying out integrity tests on filter elements by means of test gases, comprising a device housing (3), with an electronic controller (4), arranged therein for regulation and control of the progress of a test programme for filter elements, a filter housing (6), for housing a filter element (2) under test, a pneumatic unit (5), connected to the controller (4) and the filter housing (6), in particular for the generation and measurement of gas pressures, an electronic memory unit (10), which may be connected to the filter element (2) under test and a communication unit (13?), connected to the controller (4), for the exchange of data between the controller (4) and the electronic memory element (10). The communication unit (13?) is preferably embodied as an antenna (14?) and the electronic memory element (10) as a transponder (11). In addition to the device a method for carrying out integrity tests and a computer programme product are also disclosed.

Abstract: A container having flexible walls, in the interior of which container there is arranged a mixer which has a mixing element arranged at a first end of a mixer shaft, it being possible for the mixer shaft with the mixing element to be set moving longitudinally by a drive arranged outside the interior of the container, wherein the mixer shaft can be placed on the inside of a container wall with its second end facing away from the mixing element and can be fixed magnetically on the outside of the container wall, facing away from the inside, by means of a coupling piece, and wherein the coupling piece is operatively connected to a force introducing device belonging to the drive.

Abstract: The invention relates to a device for carrying out integrity tests on filter elements by means of test gases, comprising a device housing (3), with an electronic controller (4), arranged therein for regulation and control of the progress of a test programme for filter elements, a filter housing (6), for housing a filter element (2) under test, a pneumatic unit (5), connected to the controller (4) and the filter housing (6), in particular for the generation and measurement of gas pressures, an electronic memory unit (10), which may be connected to the filter element (2) under test and a communication unit (13?), connected to the controller (4), for the exchange of data between the controller (4) and the electronic memory element (10). The communication unit (13?) is preferably embodied as an antenna (14?) and the electronic memory element (10) as a transponder (11). In addition to the device a method for carrying out integrity tests and a computer programme product are also disclosed.

Abstract: A connector (10) is provided for sterile connection to a complementary connector (12). The connector (10) has a housing (14) with an engagement device (16) to engage a complementary engagement device (18) of the complementary connector (12) along an engagement direction (44). The connector (10) is displaceable relative to the complementary connector (12) along the engagement direction (44) after the engagement device (16) engages the complementary engagement device (18). The housing (14) has a feed-through opening (24) for receiving a sensor (34) and a cover (22). The cover (22) is displaced relative to the connector (10) along the engagement direction (44) to close the feed-through opening (24) in a sterile manner. The connector (10) also has a sterile sensor (34) that is movable along a sensor displacement direction (52) that differs from the engagement direction (44).