Patents by Inventor Reinhard Ebner

Reinhard Ebner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 90 human secreted proteins
    Publication number: 20060160126
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 15, 2006
    Publication date: July 20, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Daniel Soppet, Reinhard Ebner, Henrik Olsen, Paul Young, John Greene, Ann Ferrie, Guo-Liang Yu, Jian Ni, Craig Rosen, Laurie Brewer, Fouad Janat, Charles Birse
  • Antibodies to human growth factor huXAG-3 and methods of use
    Patent number: 7060801
    Abstract: The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1, huXAG-2 and huXAG-3 proteins. huXAG-1, huXAG-2 and huXAG-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of huXAG-1, huXAG-2 or huXAG-3 activity. Also provided are diagnostic and therapeutic uses of huXAG-1. huXAG-2 and huXAG-3.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: June 13, 2006
    Assignee: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Patrick J. Dillon, Reinhard Ebner, Gregory A. Endress
  • Secreted protein HRGDF73
    Patent number: 7053190
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: May 30, 2006
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Yanggu Shi
  • Cancer-linked gene as target for chemotherapy
    Publication number: 20060110731
    Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
    Type: Application
    Filed: May 15, 2003
    Publication date: May 25, 2006
    Inventor: Reinhard Ebner
  • Cancer-linked gene as target for chemotherapy
    Publication number: 20060099214
    Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
    Type: Application
    Filed: June 10, 2003
    Publication date: May 11, 2006
    Inventors: Reinhard Ebner, Paul Young
  • 186 human secreted proteins
    Publication number: 20060084082
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 6, 2005
    Publication date: April 20, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Craig Rosen, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, D. Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Carrie Fischer, Reinhard Ebner, Laurie Brewer, Paul Moore, Yanggu Shi, David LaFleur, Yi Li, ZhiZhen Zeng, Hla Kyaw
  • 98 human secreted proteins
    Publication number: 20060079670
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: September 20, 2005
    Publication date: April 13, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig Rosen, Steven Ruben, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Ying-Fei Wei, Jian Ni, Kimberly Florence, Paul Young, Laurie Brewer, Daniel Soppet, Gregory Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • 33 human secreted proteins
    Publication number: 20060036089
    Abstract: The present invention relates to 33 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 3, 2005
    Publication date: February 16, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: Daniel Soppet, Paul Moore, Yanggu Shi, Steven Ruben, Craig Rosen, David LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly Florence, Paul Young, George Komatsoulis, Jian Ni
  • Cancer-linked gene as target for chemotherapy
    Publication number: 20050287147
    Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
    Type: Application
    Filed: May 15, 2003
    Publication date: December 29, 2005
    Inventors: Reinhard Ebner, Stephen Horrigan
  • 90 human secreted proteins
    Publication number: 20050244845
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: November 12, 2004
    Publication date: November 3, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Daniel Soppet, Reinhard Ebner, Henrik Olsen, Paul Young, John Greene, Ann Ferrie, Guo-Liang Yu, Jian Ni, Craig Rosen, Laurie Brewer, Fouad Janat, Charles Birse
  • 27 human secreted proteins
    Publication number: 20050239099
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 14, 2004
    Publication date: October 27, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Jian Ni, Reinhard Ebner, Craig Rosen, Yanggu Shi, Charles Birse, Kimberly Florence, George Komatsoulis, David LaFleur, Paul Moore, Henrik Olsen, Paul Young
  • Antibodies against human protein HUVDJ43
    Patent number: 6953667
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: October 11, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
  • Cancer-linked gene as target for chemotherapy
    Publication number: 20050220798
    Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based an their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
    Type: Application
    Filed: June 4, 2003
    Publication date: October 6, 2005
    Inventors: Reinhard Ebner, Martin Shea
  • 70 human secreted proteins
    Publication number: 20050215775
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: November 2, 2004
    Publication date: September 29, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Craig Rosen, Carrie Fischer, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, D. Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Yanggu Shi
  • 86 human secreted proteins
    Publication number: 20050214844
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: April 22, 2005
    Publication date: September 29, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Moore, Yanggu Shi, Craig Rosen, Steven Ruben, David Lafleur, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Paul Young, John Greene, Ann Ferrie, Guo-Liang Yu, Jian Ni, Ping Feng
  • 29 human secreted proteins
    Publication number: 20050208619
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 29, 2004
    Publication date: September 22, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig Rosen, Steven Ruben, Reinhard Ebner, Roxanne Duan, Jian Ni, Daniel Soppet, Paul Moore, Yanggu Shi, David LaFleur, Henrik Olsen, Charles Birse, George Komatsoulis
  • 50 human secreted proteins
    Publication number: 20050208622
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 22, 2004
    Publication date: September 22, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Moore, Steven Ruben, David LaFleur, Yanggu Shi, Craig Rosen, Henrik Olsen, Reinhard Ebner, Laurie Brewer
  • Human Ependymin
    Publication number: 20050197491
    Abstract: The present invention relates to a novel human Ependymin protein which is a member of the ependymin family. In particular, isolated nucleic acid molecules are provided encoding the human Ependymin protein. Ependymin polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of Ependymin activity. Also provided are diagnostic methods for detecting nervous system-related disorders and therapeutic methods for treating nervous system-related disorders.
    Type: Application
    Filed: December 12, 2003
    Publication date: September 8, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Reinhard Ebner, Steven Ruben
  • Secreted protein HCE3C63
    Patent number: 6936691
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: August 30, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • Neutrokine-alpha and neutrokine-alpha splice variant
    Publication number: 20050186637
    Abstract: The present invention relates to nucleic acid molecules encoding Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention.
    Type: Application
    Filed: February 10, 2005
    Publication date: August 25, 2005
    Inventors: Guo-Liang Yu, Reinhard Ebner, Jian Ni, Craig Rosen, Stephen Ullrich