Patents by Inventor Remco Christiaan Den Dulk

Remco Christiaan Den Dulk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9874294
    Abstract: The invention relates to a valve (2) for controlling a passage of particles from a first region (6) to a second region (7), wherein the valve (2) comprises a valve material (4) having a modifiable degree of penetrability and a valve region (16) comprising the valve material (4), wherein the valve region (16) and the valve material (4) are adapted such that the particles have to penetrate the valve material (4) if the particles pass the valve (2) for being transferred from the first region (6) to the second region (7). The degree of opening of the valve (2) can easily be controlled by modifying the degree of penetrability of the valve material (4), for example, by modifying the temperature of the valve material (4). Moreover, by penetrating the valve material (4) the particles can be separated from other elements like a fluid containing the particles.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: January 23, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Remco Christiaan Den Dulk, Roel Penterman, Menno Willem Jose Prins
  • Patent number: 9387484
    Abstract: A method and apparatus for extracting magnetic particles from a sample includes placing the sample near a liquid carrier, which is immiscible with it, in a configuration stable under the influence of gravity. The magnetic particles are moved by a magnetic field from the sample and into the carrier. The magnetic particles are non-wetting with respect to the carrier and will therefore form agglomerates in the carrier.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: July 12, 2016
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Reinhold Wimberger-Friedl, Remco Christiaan Den Dulk
  • Patent number: 8440150
    Abstract: The present invention relates to a hydrophobic valve for liquids having an appreciable surface tension comprising magnetic particles, said device comprising at least two planar solid substrates with a functionalized surface each, wherein at least a first solid substrate has a patterned surface comprising at least two hydrophilic areas separated from one another by at least one hydrophobic area, wherein the said two planar substrates are disposed with a distance to one another in a sandwiched, parallel fashion, in such way that said functionalized surfaces are facing one another, said valve further comprising a magnetic actuator.
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: May 14, 2013
    Assignee: Koninklijke Philips Electronics N.V.
    Inventors: Remco Christiaan Den Dulk, Menno Willem Jose Prins
  • Patent number: 8349274
    Abstract: A microfluidic device includes chambers for performing chemical, biochemical, or physical processes and a flow path connecting the chambers. A magnetic particle is moved through the chambers which are separated by a valve-like structure that enables passing-through of the magnetic particle from one chamber to another. At least one delaying structure delays movement of the magnetic particle along the flow path.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: January 8, 2013
    Assignee: Koninklijke Philips Electronic N.V.
    Inventors: Menno Willem Jose Prins, Pieter Jan Van Der Zaag, Remco Christiaan Den Dulk
  • Publication number: 20120270332
    Abstract: The invention relates to means for extracting magnetic particles (M) from a sample (S). The sample (S) is arranged adjacent to a liquid carrier (C), which is immiscible with it, in a configuration stable under the influence of gravity, and the magnetic particles (M) are moved by a magnetic field (B) from the sample (S) into the carrier (C). Preferably, the magnetic particles (M) are non-wetting with respect to the carrier (C) and will therefore form agglomerates in the carrier (C).
    Type: Application
    Filed: September 27, 2010
    Publication date: October 25, 2012
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Reinhold Wimberger-Friedl, Remco Christiaan Den Dulk
  • Publication number: 20110240130
    Abstract: The present invention relates to a hydrophobic valve for liquids having an appreciable surface tension comprising magnetic particles, said device comprising at least two planar solid substrates with a functionalized surface each, wherein at least a first solid substrate has a patterned surface comprising at least two hydrophilic areas separated from one another by at least one hydrophobic area, wherein the said two planar substrates are disposed with a distance to one another in a sandwiched, parallel fashion, in such way that said functionalized surfaces are facing one another, said valve further comprising a magnetic actuator.
    Type: Application
    Filed: June 17, 2009
    Publication date: October 6, 2011
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Remco Christiaan Den Dulk, Menno Willem Jose Prins
  • Publication number: 20110171086
    Abstract: A microfluidic device is provided, the microfluidic device comprising: a plurality of chambers (3, 4, 5, 6) adapted for performing chemical, biochemical, or physical processes and a flow path (9) connecting the plurality of chambers (3, 4, 5, 6) adapted for accommodating at least one magnetic particle (7) subsequently moving through the plurality of chambers The plurality of chambers (3, 4, 5, 6) are separated by at least one valve-like structure (10) adapted to enable passing-through of the at least one magnetic particle (7) from one of the plurality of chambers to another one of the plurality of chambers. At least one delaying structure (11, 111) adapted to delay movement of the at least one magnetic particle (7) along the flow path is provided.
    Type: Application
    Filed: October 1, 2009
    Publication date: July 14, 2011
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Menno Willem Jose Prins, Pieter Jan Van Der Zaag, Remco Christiaan Den Dulk