Patents by Inventor Remigio Piergallini

Remigio Piergallini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biophotonic compositions for the treatment of otitis externa
    Patent number: 10610513
    Abstract: The present disclosure describes methods and uses of biophotonic compositions which comprise at least one oxidant and at least one chromophore capable of activating the oxidant, in association with a pharmacologically acceptable carrier for the treatment of otitis externa.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: April 7, 2020
    Assignee: KLOX TECHNOLOGIES LIMITED
    Inventors: Francesco Bellini, Matteo Cerquetella, Adolfo Maria Tambella, Andrea Spaterna, Nikolaos Loupis, David Ohayon, Remigio Piergallini
  • ABSORBENT BIOPHOTONIC DEVICES AND SYSTEMS FOR WOUND HEALING
    Publication number: 20200085625
    Abstract: The present technology generally relates to products, devices, methods and systems for healing of wounds or for wound-treatment therapies. More particularly, but not by way of limitation, the present technology relates an absorbent product impregnated with photoactivatable agents, or light-absorbing molecules, as photoactivatable inserts as wound dressing that can be used together as part of negative-pressure wound therapy (NPWT) system or separately and without the NPWT system.
    Type: Application
    Filed: May 4, 2018
    Publication date: March 19, 2020
    Inventors: Carlo BELLINI, Nikolaos LOUPIS, Remigio PIERGALLINI, David OHAYON
  • METHODS FOR PHOTOBIOMODULATION OF BIOLOGICAL PROCESSES USING FLUORESCENCE GENERATED AND EMITTED FROM A BIOPHOTONIC COMPOSITION OR A BIOPHOTONIC SYSTEM
    Publication number: 20190381173
    Abstract: According to various aspects, the present technology provides for the use of fluorescence generated and emitted from a biophotonic composition or system, wherein said fluorescence results from induction of one or more light-absorbing molecules found in the composition or system, wherein said emitted fluorescence is reaching a cell or tissue in order to modulate one or more biological processes within said cell or tissue.
    Type: Application
    Filed: January 26, 2018
    Publication date: December 19, 2019
    Inventors: Michael CANOVA ENGELBRECHT NIELSEN, Remigio PIERGALLINI, Nikolaos LOUPIS, Joanna JAWORSKA, Emmanuelle DEVEMY, Giovanni SCAPAGNINI
  • COMBINATION OF AN OXIDANT AND A PHOTOACTIVATOR FOR THE WOUNDS
    Publication number: 20190366113
    Abstract: There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed.
    Type: Application
    Filed: August 9, 2019
    Publication date: December 5, 2019
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, Francesco BELLINI
  • BIOPHOTONIC COMPOSITIONS COMPRISING LICHEN EXTRACT AND THEIR USE TO TREAT SKIN DISORDERS
    Publication number: 20190358327
    Abstract: The present disclosure provides biophotonic compositions comprising a lichen extract and a carrier medium and methods and uses thereof.
    Type: Application
    Filed: December 22, 2017
    Publication date: November 28, 2019
    Inventors: David OHAYON, Paschalis PASCHALAKIS, Remigio PIERGALLINI, Nikolaos LOUPIS
  • BIOPHOTONIC METHODS FOR INCREASING IN SITU ENERGY PRODUCTION AND ENERGY EMISSION IN BIOLOGICAL CELLS AND TISSUES
    Publication number: 20190360993
    Abstract: The present technology generally relates to a method for modulating in situ production of energy by a biological tissue. The method comprises stimulating the biological tissue by exposing the biological tissue to a photostimulated biophotonic composition for a time sufficient to initiate the production of energy by the biological tissue.
    Type: Application
    Filed: February 8, 2018
    Publication date: November 28, 2019
    Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI, David OHAYON, Lise HÉBERT, Giovanni SCAPAGNINI
  • BIOPHOTONIC COMPOSITIONS AND METHODS FOR PROVIDING BIOPHOTONIC TREATMENT
    Publication number: 20190358142
    Abstract: The present disclosure provides biophotonic topical compositions and methods useful in phototherapy. In particular, the biophotonic topical compositions of the present disclosure are substantially resistant to leaching such that very low amounts of chromophore(s) present in the biophotonic composition leach out of the composition. The biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Application
    Filed: August 9, 2019
    Publication date: November 28, 2019
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, Shipra RASTOGI
  • Methods and compositions for treatment of pigmented lesions
    Patent number: 10485986
    Abstract: There is provided a method for treating pigmented lesions comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant. The composition may further comprise at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: November 26, 2019
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease
    Patent number: 10471147
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: November 12, 2019
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • COMBINATION OF AN OXIDANT, A PHOTOSENSITIZER AND A WOUND HEALING AGENT FOR ORAL DISINFECTION AND TREATMENT OF ORAL DISEASE
    Publication number: 20190269777
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Application
    Filed: May 16, 2019
    Publication date: September 5, 2019
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS
  • Combination of an oxidant and a photoactivator for the healing of wounds
    Patent number: 10384072
    Abstract: There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: August 20, 2019
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Biophotonic compositions and methods for providing biophotonic treatment
    Patent number: 10376455
    Abstract: The present disclosure provides biophotonic topical compositions and methods useful in phototherapy. In particular, the biophotonic topical compositions of the present disclosure are substantially resistant to leaching such that very low amounts of chromophore(s) present in the biophotonic composition leach out of the composition. The biophotonic compositions and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: August 13, 2019
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Shipra Rastogi
  • BIOPHOTONIC COMPOSITIONS AND METHODS FOR REDUCING SCARRING
    Publication number: 20190224317
    Abstract: The present disclosure relates to methods for reducing scarring of wounds. The methods comprising topically applying on the wound a biophotonic composition followed by illumination of the applied biophotonic composition with actinic light, wherein the method comprises the following schedule: (a) a period of from about 1 day to about 4 weeks during which, at least once every week the biophotonic composition is topically applied onto the wound and is illuminated for a period of at least 5 minutes, followed by a rest period of less than about a week; and (b) repeating step (a) over a period of at least 4 weeks.
    Type: Application
    Filed: September 22, 2017
    Publication date: July 25, 2019
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, Andreas NIKOLIS, Stéphane FAUVERGHE, Lise HEBERT, Francesco BELLINI
  • BIOPHOTONIC COMPOSITIONS, METHODS, AND KITS FOR INHIBITING AND DISRUPTING BIOFILMS
    Publication number: 20190209683
    Abstract: The present document describes methods of using compositions for inhibiting biofilm formation, or disrupting existing or developing biofilms in a subject, which composition comprises at least one chromophore and a pharmacologically acceptable carrier.
    Type: Application
    Filed: September 22, 2017
    Publication date: July 11, 2019
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, David OHAYON, Kevin WILKINSON, Giovanni SCAPAGNINI
  • Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease
    Patent number: 10322179
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: June 18, 2019
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • METHODS AND COMPOSITIONS FOR TREATMENT OF PIGMENTED LESIONS
    Publication number: 20190143137
    Abstract: There is provided a method for treating rosacea comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 5, 2018
    Publication date: May 16, 2019
    Inventors: Remigio PIERGALLINI, Nikolaos LOUPIS, Francesco BELLINI
  • CHROMOPHORE COMBINATIONS FOR BIOPHOTONIC USES
    Publication number: 20190133908
    Abstract: The present disclosure provides biophotonic compositions and methods useful in phototherapy. In particular, the biophotonic compositions of the present disclosure comprise at least two xanthene dyes. The biophotonic compositions and method of the disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and other skin conditions.
    Type: Application
    Filed: December 19, 2018
    Publication date: May 9, 2019
    Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI
  • Chromophore combinations for biophotonic uses
    Patent number: 10213373
    Abstract: The present disclosure provides biophotonic compositions and methods useful in phototherapy. In particular, the biophotonic compositions of the present disclosure comprise at least two xanthene dyes. The biophotonic compositions and the method of the disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and other skin conditions.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: February 26, 2019
    Assignee: KLOX TECHNOLOGIES, INC.
    Inventors: Nikolaos Loupis, Remigio Piergallini
  • BIOPHOTONIC MATERIALS AND USES THEREOF
    Publication number: 20190046643
    Abstract: The present disclosure provides topical biophotonic materials and methods useful in phototherapy. In particular, the topical biophotonic materials of the present disclosure include a cohesive matrix, and at least one chromophore which can absorb and emit light from within the topical biophotonic material, wherein the topical biophotonic material is elastic. The topical bio-photonic materials and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
    Type: Application
    Filed: October 16, 2018
    Publication date: February 14, 2019
    Inventors: Nikolaos LOUPIS, Remigio PIERGALLINI, Eric DESROSIERS
  • BIOPHOTONIC COMPOSITIONS FOR THE TREATMENT OF OTITIS EXTERNA
    Publication number: 20190029994
    Abstract: The present disclosure describes methods and uses of biophotonic compositions which comprise at least one oxidant and at least one chromophore capable of activating the oxidant, in association with a pharmacologically acceptable carrier for the treatment of otitis externa.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 31, 2019
    Inventors: Francesco BELLINI, Matteo CERQUETELLA, Adolfo Maria TAMBELLA, Andrea SPATERNA, Nikolaos LOUPIS, David OHAYON, Remigio PIERGALLINI