Patents by Inventor Rena S. Lapidus

Rena S. Lapidus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NAALADase inhibitors useful as pharmaceutical compounds and compositions
    Publication number: 20030083374
    Abstract: The present invention relates to N-Acetylated &agr;-Linked Acidic Dipeptidase (NAALADase) inhibitors enzyme activity, pharmaceutical compositions comprising such inhibitors, and methods of their use to inhibit NAALADase enzyme activity, thereby effecting neuronal activities, inhibiting angiogenesis, and treating glutamate abnormalities, compulsive disorders, prostate diseases, pain and diabetic neuropathy.
    Type: Application
    Filed: June 10, 2002
    Publication date: May 1, 2003
    Inventors: Paul F. Jackson, Keith M. Maclin, Eric Wang, Barbara S. Slusher, Rena S. Lapidus, Pavel Majer
  • NAALADase inhibitors useful as pharmaceutical compounds and compositions
    Patent number: 6458775
    Abstract: The present invention relates to N-Acetylated &agr;-Linked Acidic Dipeptidase (NAALADase) inhibitors enzyme activity, pharmaceutical compositions comprising such inhibitors, and methods of their use to inhibit NAALADase enzyme activity, thereby effecting neuronal activities, inhibiting angiogenesis, and treating glutamate abnormalities, compulsive disorders, prostate diseases, pain and diabetic neuropathy.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: October 1, 2002
    Assignee: Guilford Pharmaceutical Inc.
    Inventors: Paul F. Jackson, Keith M. Maclin, Eric Wang, Barbara S. Slusher, Rena S. Lapidus, Pavel Majer
  • Use of NAALADase activity to identify prostate cancer and benign prostatic hyperplasia
    Patent number: 5981209
    Abstract: The present invention relates to novel methods and kits for quantitating N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity in biological samples, including prostate biopsies, seminal fluid, ejaculate, prostatic fluid, blood, saliva, and urine, for the purpose of identifying and differentiating between prostate carcinoma, benign prostatic hyperplasia, and normal prostate.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: November 9, 1999
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Barbara S. Slusher, Rena S. Lapidus