Abstract: The invention relates to improved apparatus for filling containers with liquid and/or paste substances under sterile conditions, and comprises a filler-valve (1) giving out directly into an enclosed sterile chamber (4) whose bottom-opening (5) affords access to the neck (6) of single containers (7) to be filled. Provision is made for a device (60) which lays hold on the container neck (6) when inserted into the opening (5) thus keeping the same in vertical alignment below the valve (1), and for at least one plate whose function is that of closing-off the opening (5) automatically whenever no container is offered thereto for the purpose of being filled.