Abstract: An objective of the present invention is to provide a liver disease regulatory formulation, which is beneficial to prevent the occurrence and development of a chronic liver disease by remodeling a liver regeneration microenvironment. The liver disease regulatory formulation, comprises a hepatocyte-derived liver progenitor cell or a secretory supernatant of the hepatocyte-derived liver progenitor cell.

Abstract: A spindle thermal error compensation method which is insensitive to the disturbance of the cooling system is provided, belonging to the technical field of error compensation in numerical control machine tools. First, the spindle model coefficient identification test, based on multi-state speed variable, is performed; after which, based on the correlation analysis between temperature and thermal error, the temperature measurement point, significantly correlated with the axial thermal error of the spindle, is determined. Next, a spindle thermal error model is established, which is insensitive to the cooling system disturbance. In addition, the coefficients in the model are identified under constraint condition, according to the nonlinear quadratic programming algorithm. Finally, based on the OPC UA communication protocol, the compensation value, as calculated by the model, is input to the numerical control system, in order to realize the compensation of the spindle thermal error.

Abstract: An on line prediction method of part surface roughness based on SDAE-DBN algorithm. The tri-axis acceleration sensor is adsorbed on the rear bearing of the machine tool spindle through the magnetic seat to collect the vibration signals of the cutting process, and a microphone is placed in the left front of the processed part to collect the noise signals of the cutting process of the machine tool; the trend term of dynamic signal is eliminated, and the signal is smoothed; a stacked denoising autoencoder is constructed, and the greedy algorithm is used to train the network, and the extracted features are used as the input of deep belief network to train the network; the real-time vibration and noise signals in the machining process are input into the deep network after data processing, and the current surface roughness is set as output by the network.

Abstract: A spindle thermal error compensation method which is insensitive to the disturbance of the cooling system is provided, belonging to the technical field of error compensation in numerical control machine tools. First, the spindle model coefficient identification test, based on multi-state speed variable, is performed; after which, based on the correlation analysis between temperature and thermal error, the temperature measurement point, significantly correlated with the axial thermal error of the spindle, is determined. Next, a spindle thermal error model is established, which is insensitive to the cooling system disturbance. In addition, the coefficients in the model are identified under constraint condition, according to the nonlinear quadratic programming algorithm. Finally, based on the OPC UA communication protocol, the compensation value, as calculated by the model, is input to the numerical control system, in order to realize the compensation of the spindle thermal error.

Abstract: Techniques are described for use by an implantable medical device equipped to use trim values, which allow the device to continue to use trim values despite certain memory errors such as parity errors. Briefly, optimal trim values are stored within RAM. Nominal trim values are stored within ROM. Device functions are then performed using the trim values stored within RAM. If an error is detected indicative of possible corruption of RAM, then the trim values from ROM are loaded into RAM to enable continued operation of the device using the nominal trim values despite the error. In a preferred implementation, the optimized trim values are initially stored at two separate locations within RAM. A procedure is described herein for allowing the device to continue to use the optimized trim values following a device reset if no parity error is detected. If a parity error occurred, the device instead uses the nominal trim values from ROM.