Abstract: The invention describes a method for continuous or intermittent wireless monitoring of the volume of cardiac chambers, with the ability to combine these with pressure measurements for optimal remote monitoring of cardiac patients. The invention comprises a set of wireless sensors such as resonators or reflectors placed within a cardiac chamber (i.e., the left ventricle), means for sensing the pressure within one or more cardiac chamber, and an external device adapted to interrogate the wireless sensors, determine their relative and/or absolute positions with respect to each other and/or the external device, and calculating the resulting volume of the cardiac chamber and creating pressure-volume loops.

Abstract: Disclosed are apparatus, method, devices and instruments, including an apparatus that includes a flexible waveguide coupled to a supporting structure, and further coupled to a treatment tip. The apparatus also includes a beam controller to control application of a radiation beam emitted from the flexible waveguide to distribute the beam over an area different than an area covered by direct application of the beam to a single location on a target tissue. Further disclosed is an apparatus that includes a waveguide, coupleable to a laser source, and a thermal protection instrument. The thermal protection instrument includes a tissue contacting member to contact a part of an area of a tissue irradiated by laser radiation, and a beam blocking element to absorb at least some of radiation not absorbed by the area of the tissue, the beam blocking element being thermally isolated from the area of the tissue.

Abstract: Disclosed are apparatus, method, devices and instruments, including an apparatus that includes a flexible waveguide coupled to a supporting structure, and further coupled to a treatment tip. The apparatus also includes a beam controller to control application of a radiation beam emitted from the flexible waveguide to distribute the beam over an area different than an area covered by direct application of the beam to a single location on a target tissue. Further disclosed is an apparatus that includes a waveguide, coupleable to a laser source, and a thermal protection instrument. The thermal protection instrument includes a tissue contacting member to contact a part of an area of a tissue irradiated by laser radiation, and a beam blocking element to absorb at least some of radiation not absorbed by the area of the tissue, the beam blocking element being thermally isolated from the area of the tissue.

Abstract: Disclosed is an apparatus that includes a modifiable fiber structure adapted to operate in at least two configurations such that is a sideways-firing configuration the fiber structure is adapted to emit radiation in a substantially sideways direction relative to a longitudinal axis of the fiber structure, and in another, axial-firing, configuration the fiber structure is adapted to emit radiation in substantially axial direction relative to the longitudinal axis of the fiber structure. Also disposed is another apparatus that includes a guide tube disposed within a scope, the guide tube configured to be advanced to a position near an area to be treated so that the scope can be advanced along the guide tube to the position near the area to be treated. The guide tube is further configured to receive a treatment instrument to perform a treatment procedure on the area to be treated.

Abstract: Disclosed are apparatus, method, devices and instruments, including an apparatus that includes a flexible waveguide coupled to a supporting structure, and further coupled to a treatment tip. The apparatus also includes a beam controller to control application of a radiation beam emitted from the flexible waveguide to distribute the beam over an area different than an area covered by direct application of the beam to a single location on a target tissue. Further disclosed is an apparatus that includes a waveguide, coupleable to a laser source, and a thermal protection instrument. The thermal protection instrument includes a tissue contacting member to contact a part of an area of a tissue irradiated by laser radiation, and a beam blocking element to absorb at least some of radiation not absorbed by the area of the tissue, the beam blocking element being thermally isolated from the area of the tissue.

Abstract: Disclosed are apparatus, systems, devices, methods and structures, including an apparatus that includes a device including an inner channel, and a fiber structure comprising an energy-transmitting fiber and a cover surrounding the energy-transmitting fiber, the energy transmitting fiber including an end that is substantially flush with the cover such that the fiber structure can be passed through the inner channel of the device.

Abstract: Disclosed are apparatus, method, devices and instruments, including an apparatus that includes a flexible waveguide coupled to a supporting structure, and further coupled to a treatment tip. The apparatus also includes a beam controller to control application of a radiation beam emitted from the flexible waveguide to distribute the beam over an area different than an area covered by direct application of the beam to a single location on a target tissue. Further disclosed is an apparatus that includes a waveguide, coupleable to a laser source, and a thermal protection instrument. The thermal protection instrument includes a tissue contacting member to contact a part of an area of a tissue irradiated by laser radiation, and a beam blocking element to absorb at least some of radiation not absorbed by the area of the tissue, the beam blocking element being thermally isolated from the area of the tissue.

Abstract: Disclosed are radiation systems and methods, including a system that includes a waveguide to direct radiation from a first radiation source, a covering to cover at least part of the waveguide and one or more optical fibers embedded in the covering to direct radiation from a second radiation source. Also disclosed is system that includes a hollow waveguide assembly including a proximal portion and a distal portion that can be coupled to the proximal portion at a coupling area, the hollow waveguide assembly being configured to direct radiation from a first radiation source to an output port at a distal end of the distal portion of the hollow waveguide assembly, and a coupling unit to couple into the distal portion of the hollow waveguide assembly radiation from a second radiation source and the radiation from the first source delivered through the proximal portion.

Abstract: Disclosed is a treatment device. The treatment device includes a treatment tip that includes one or more members with contacting surfaces to contact a target area, the tip being mechanically coupled to a body member. The tip also includes one or more heating elements placed on at least one of the one or more members of the treatment tip, the one or more heating elements configured to be heated by laser radiation and to direct heat to treat at least a portion of the target area.

Abstract: Disclosed is an apparatus that includes a modifiable fiber structure adapted to operate in at least two configurations such that in a sideways-firing configuration the fiber structure is adapted to emit radiation in a substantially sideways direction relative to a longitudinal axis of the fiber structure, and in another, axial-firing, configuration the fiber structure is adapted to emit radiation in a substantially axial direction relative to the longitudinal axis of the fiber structure. Also disclosed is another apparatus that includes a guide tube disposed within a scope, the guide tube configured to be advanced to a position near an area to be treated so that the scope can be advanced along the guide tube to the position near the area to be treated. The guide tube is further configured to receive a treatment instrument to perform a treatment procedure on the area to be treated.