Patents by Inventor Rey-Yuh Wu

Rey-Yuh Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11020447
    Abstract: Disclosed herein are methods for treating type II diabetes mellitus. In particular, the present invention relates to methods of using an extract of Hedychium coronarium Koenig and a blood glucose reduction agent, to synergistically reduce the blood glucose level of the subject having type II diabetes mellitus.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: June 1, 2021
    Assignee: VITNOVO, INC.
    Inventors: Pei-Ran Wang, Rey-Yuh Wu, Yu-Yuan Wu, Lung-Yu Kuan, Klim King
  • Patent number: 10561700
    Abstract: The present invention is related to the use of an overground part of Hedychium coronarium Koenig in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes without overly reducing blood glucose in a subject; i.e., not reducing blood glucose in a fasting subject. The present invention also relates to an extract and composition of the overground part of Hedychium coronarium Koenig and its use in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: February 18, 2020
    Assignee: Development Center for Biotechnology
    Inventors: Rey Yuh Wu, Yu-Yuan Wu, Lung-Yu Kuan, Klim King
  • Publication number: 20190183959
    Abstract: Disclosed herein are methods for treating type II diabetes mellitus. In particular, the present invention relates to methods of using an extract of Hedychium coronarium Koenig and a blood glucose reduction agent, to synergistically reduce the blood glucose level of the subject having type II diabetes mellitus.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 20, 2019
    Applicant: VITNOVO, INC.
    Inventors: Pei-Ran WANG, Rey-Yuh WU, Yu-Yuan WU, Lung-Yu KUAN, Klim KING
  • Publication number: 20180140653
    Abstract: Disclosed herein are methods for treating type II diabetes mellitus. In particular, the present invention relates to methods of using an extract of Hedychium coronarium Koenig and a blood glucose reduction agent, to synergistically reduce the blood glucose level of the subject having type II diabetes mellitus.
    Type: Application
    Filed: December 18, 2017
    Publication date: May 24, 2018
    Applicant: VITNOVO, INC.
    Inventors: Pei-Ran WANG, Rey-Yuh WU, Yu-Yuan WU, Lung-Yu KUAN, Klim KING
  • Patent number: 9872879
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: January 23, 2018
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Publication number: 20170087201
    Abstract: The present invention is related to the use of an overground part of Hedychium coronarium Koenig in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes without overly reducing blood glucose in a subject; i.e., not reducing blood glucose in a fasting subject. The present invention also relates to an extract and composition of the overground part of Hedychium coronarium Koenig and its use in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes.
    Type: Application
    Filed: November 22, 2016
    Publication date: March 30, 2017
    Inventors: Rey Yuh Wu, Yu-Yuan Wu, Lung-Yu Kuan, Klim King
  • Patent number: 9295705
    Abstract: This invention relates to methods for treatment of nephritis. This invention further provides a method of treating with nephritis comprising administering to the subject an amount of herbal pharmaceutical composition thereof effective to treat the subject. Move particularly, this invention provides an herbal pharmaceutical composition comprising Rhizoma Atractylodis macrocephalae, Eucommiae cortex, Lonicerae caulis, and Hedyotidis diffusae Herba thereof for use in treating a subject afflicted with active nephritis.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: March 29, 2016
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Ann Chen, Shuk-Man Ka, Rey-Yuh Wu, Jia-Ming Chang
  • Patent number: 9150482
    Abstract: A compound for controlling blood glucose level has a structure shown in Formula I: wherein R5-R8 are as defined herein. A method for controlling blood glucose level includes administering to a subject in need thereof a compound of Formula I. The method further includes administering to the subject a GLP-1 receptor ligand. The compound and the GLP-1 receptor ligand may be administered together. The compound may be Galanal A or Galanal B. The GLP-1 receptor ligand may be GLP-1 or exendin-4.
    Type: Grant
    Filed: June 6, 2013
    Date of Patent: October 6, 2015
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Hui-Ling Chen, Yu-Yuan Wu, Jiann-Jyh Huang, Shoei-Sheng Lee, K-Lim King
  • Patent number: 9023407
    Abstract: The present invention relates to a plant extract for treating diabetes and a process for making same. The plant extract of the invention is prepared from an overground part of Hedychium coronarium Koenig, which has the efficacies of lowering blood glucose, increasing insulin levels, reducing insulin resistance and treating and/or preventing diabetes without overly reducing blood glucose in a subject, i.e., not reducing blood glucose in a fasting subject. Also provided herein is a method for treating diabetes in a subject in need thereof comprising administering an effective amount of the plant extract to the subject.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: May 5, 2015
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Hui-Ling Chen, Yu-Yuan Wu, Lung-Yu Kuan, Chao-Tsen Lu, Shoei-Sheng Lee
  • Publication number: 20130331323
    Abstract: A compound for controlling blood glucose level has a structure shown in Formula I: wherein R5-R8 are as defined herein. A method for controlling blood glucose level includes administering to a subject in need thereof a compound of Formula I. The method further includes administering to the subject a GLP-1 receptor ligand. The compound and the GLP-1 receptor ligand may be administered together. The compound may be Galanal A or Galanal B. The GLP-1 receptor ligand may be GLP-1 or exendin-4.
    Type: Application
    Filed: June 6, 2013
    Publication date: December 12, 2013
    Applicant: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Hui-Ling Chen, Yu-Yuan Wu, Jiann-Jyh Huang, Shoei-Sheng Lee, K-Lim King
  • Publication number: 20130309337
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Application
    Filed: April 29, 2013
    Publication date: November 21, 2013
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: REY-YUH WU, YUH-SHAN CHUNG, YU-YUAN WU, MA-LI SIU, CHIN-WEN HSIAO
  • Patent number: 8449924
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: May 28, 2013
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Publication number: 20130040004
    Abstract: The present invention relates to a plant extract for treating diabetes and a process for making same. The plant extract of the invention is prepared from an overground part of Hedychium coronarium Koenig, which has the efficacies of lowering blood glucose, increasing insulin levels, reducing insulin resistance and treating and/or preventing diabetes without overly reducing blood glucose in a subject, i.e., not reducing blood glucose in a fasting subject. Also provided herein is a method for treating diabetes in a subject in need thereof comprising administering an effective amount of the plant extract to the subject.
    Type: Application
    Filed: August 8, 2012
    Publication date: February 14, 2013
    Applicant: Development Center for Biotechnology
    Inventors: Rey-Yuh WU, Hui-Ling Chen, Yu-Yuan Wu, Lung-Yu Kuan, Chao-Tsen Lu, Shoei-Sheng Lee
  • Patent number: 8247004
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: August 21, 2012
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Publication number: 20120114678
    Abstract: This invention relates to methods for treatment of nephritis. This invention further provides a method of treating with nephritis comprising administering to the subject an amount of herbal pharmaceutical composition thereof effective to treat the subject. Move particularly, this invention provides an herbal pharmaceutical composition comprising Rhizoma Atractylodis macrocephalae, Eucommiae cortex, Lonicerae caulis, and Hedyotidis diffusae Herba thereof for use in treating a subject afflicted with active nephritis.
    Type: Application
    Filed: November 7, 2011
    Publication date: May 10, 2012
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: ANN CHEN, SHUK-MAN KA, REY-YUH WU, JIA-MING CHANG
  • Publication number: 20120009281
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Application
    Filed: June 15, 2011
    Publication date: January 12, 2012
    Inventors: Rey-Yuh WU, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Publication number: 20110195139
    Abstract: The present invention is related to the use of an overground part of Hedychium coronarium Koenig in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes without overly reducing blood glucose in a subject; i.e., not reducing blood glucose in a fasting subject. The present invention also relates to an extract and composition of the overground part of Hedychium coronarium Koenig and its use in lowering blood glucose, increasing insulin levels and treating and/or preventing diabetes.
    Type: Application
    Filed: January 27, 2011
    Publication date: August 11, 2011
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey Yuh Wu, Yu-Yuan Wu, Lung-Yu Kuan, Klim King
  • Patent number: 7985431
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: July 26, 2011
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Patent number: 7824714
    Abstract: The present invention relates to a Polygonum multiflorum extract and the preparation process thereof. The Polygonum multiflorum extract of the present invention mainly comprises 2,3,5,4?-tetrahydroxystilbene-2-O-?-D-glucoside and catechin. The present invention also relates to the use of the Polygonum multiflorum extract of the present invention for the treatment or prevention of dementia.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: November 2, 2010
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Tzung-Hsien Lai, Yau-Jan Chyan, Chia-Yu Yen
  • Publication number: 20090324751
    Abstract: The present invention relates to a Polygonum multiflorum extract and the preparation process thereof. The Polygonum multiflorum extract of the present invention mainly comprises 2,3,5,4?-tetrahydroxystilbene-2-O-?-D-glucoside and catechin. The present invention also relates to the use of the Polygonum multiflorum extract of the present invention for the treatment or prevention of dementia.
    Type: Application
    Filed: June 13, 2008
    Publication date: December 31, 2009
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey-Yuh WU, Tzung-Hsien Lai, Yau-Jan Chyan, Chia-Yu Yen