Abstract: Described herein are compounds that are useful in treating a USP7-mediated disorder. In some embodiments, the USP7-mediated disorder is cancer.

Abstract: A Magnetic Resistance Apparatus (MRA) for providing manageable resistance, the MRA comprising a series of magnets disposed adjacent from one another, a series of electromagnets slidably mounted in electromagnetic cooperation with the series of magnets and an actuator for sliding the series of electromagnets in respect with the series of magnets, wherein current in the electromagnets is managed in a non-constant fashion along the sliding of the series of electromagnets in respect with the series of magnets.

Abstract: An insulating panel attachable to a building, the building defining a building aperture, the building aperture defining an aperture plane extending substantially thereacross. The insulating panel includes a membrane structure defining a first external wall and a substantially opposed second external wall; a peripheral wall extending between the first and second external walls, the first external wall, second external wall and peripheral wall together defining an enclosure; and an internal wall system located between the first and second external walls, the internal wall system being configured so as to divide the enclosure into a first cell located substantially adjacent to the first external wall and a second cell located substantially adjacent to the second external wall, the first and second cells being substantially spaced apart respectively from the second and first external walls by the internal wall system.

Abstract: An insulating panel attachable to a building, the building defining a building aperture, the building aperture defining an aperture plane extending substantially thereacross. The insulating panel includes a membrane structure defining a first external wall and a substantially opposed second external wall; a peripheral wall extending between the first and second external walls, the first external wall, second external wall and peripheral wall together defining an enclosure; and an internal wall system located between the first and second external walls, the internal wall system being configured so as to divide the enclosure into a first cell located substantially adjacent to the first external wall and a second cell located substantially adjacent to the second external wall, the first and second cells being substantially spaced apart respectively from the second and first external walls by the internal wall system.