Patents by Inventor Ricardo Mondragon Gonzalez

Ricardo Mondragon Gonzalez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced differentiation and maturation of pluripotent stem cell-derived myogenic cells
    Patent number: 11697798
    Abstract: A method to increase the efficiency of myotube generation and maturation from pluripotent stem cells comprising: (a) differentiating pluripotent stem cells to myogenic progenitors; and (b) terminally differentiating said myogenic progenitors from (a) into myotubes in the presence of at least one gamma secretase inhibitor, wherein myotube generation is increased in the presence of at least one gamma secretase inhibitor, as compared to differentiation in the absence of gamma secretase inhibitors.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: July 11, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Rita Perlingeiro, Sridhar Selvaraj, Ricardo Mondragon Gonzalez
  • ENHANCED DIFFERENTIATION AND MATURATION OF PLURIPOTENT STEM CELL-DERIVED MYOGENIC CELLS
    Publication number: 20210171911
    Abstract: A method to increase the efficiency of myotube generation and maturation from pluripotent stem cells comprising: (a) differentiating pluripotent stem cells to myogenic progenitors; and (b) terminally differentiating said myogenic progenitors from (a) p into myotubes in the presence of at least one gamma secretase inhibitor, wherein myotube generation is increased in the presence of at least one gamma secretase inhibitor, as compared to differentiation in the absence of gamma secretase inhibitors.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 10, 2021
    Inventors: Rita Perlingeiro, Sridhar Selvaraj, Ricardo Mondragon Gonzalez