Abstract: The present invention provides a compound of Formula I. or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating metabolic conditions, such as type 2 diabetes mellitus, heart failure, diabetic kidney disease, and non-alcoholic steatohepatitis.

Abstract: The present disclosure relates to plant-based protein compositions that when used in a beverage, create a beverage product with a superior mouthfeel.

Abstract: Vibration absorbers comprising torsional viscous damper of the tube-type are tuned using one or more elastic members to improve the ability of the vibration absorbers to reduce problematic torsional vibrations. The torsional stiffness of the vibration absorbers is designed to meet a requirement between the frequency to be removed and the polar moment of inertia of the tube-type damper.

Abstract: A hemofilter system. In one embodiment, the hemofilter system includes a container having a first surface, a second surface, and one or more wall surfaces, the first surface, the second surface and the one or more wall surfaces defining a volume; an input port in fluid communication with the first surface; an output port in fluid communication with the second surface; a filter bed comprising a plurality of planar magnetic meshes stacked in close juxtaposition and positioned within the container volume and coplanar with the first and second surfaces; a first magnet positioned on a first surface of the container; a second magnet positioned on the second surface of the container; a first input conduit in fluid communication with the input port; and a first output conduit in fluid communication with the output port. In another embodiment, the hemofilter system includes a pump in the input conduit.

Abstract: The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae I, II and III wherein Q is selected from the group consisting of —P(O)(OH)2, —P(O)(OH)(O?M+), —P(O)(O?M+)2 and —P(O)(O?)2M2+; M+ at each occurrence is a pharmaceutically acceptable monovalent cation; and M2+ is a pharmaceutically acceptable divalent cation and their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for predicting a structure of a protein that comprises a plurality of amino acid chains.

Abstract: In particular embodiments, a computing system may capture a first image of a scene using a first camera of an artificial reality device. The system may capture a second image of the scene using a second camera and one or more optical elements of the artificial reality device. The second image may include an overlapping portion of multiple shifted copies of the scene. The system may generate an upsampled first image by applying a particular sampling technique to the first image. The system may generate a tiled image comprising a plurality of repeated second images by applying a tiling process to the second image. The system may generate an initial output image by processing the upsampled first image and the tiled image using a machine learning model. The system may generate a final output image by normalizing the initial output image using the upsampled first image.

Abstract: The present disclosure provides three-dimensional (3D) printing systems, apparatuses, software, and methods for the production of at least one requested 3D object. The 3D printer includes a material conveyance system, filtering system, and/or an unpacking station. The material conveyance system may transport pre-transformed material (e.g., powder) against gravity. The 3D printing described herein facilitated reducing interruptions of (e.g., providing non interrupted) (ii) material recycling, and/or (i) material dispensing through a component of the 3D printer such as a layer dispenser. The material conveyance system may operate above ambient pressure, e.g., while performing a suction operation. The present disclosure provides three-dimensional (3D) printing processes, apparatuses, software, and systems for controlling and/or treating gas and gas borne debris in an atmosphere of a 3D printer.